scholarly journals Classification of breast lesions in ultrasonography using sparse logistic regression and morphology-based texture features

2018 ◽  
Vol 45 (9) ◽  
pp. 4112-4124 ◽  
Author(s):  
Hoda Nemat ◽  
Hamid Fehri ◽  
Nasrin Ahmadinejad ◽  
Alejandro F. Frangi ◽  
Ali Gooya
2020 ◽  
Author(s):  
Mariusz Nieniewski ◽  
Leszek J. Chmielewski

Most of the methods of classification of breast lesions in ultrasound (US) images have been tested on B-mode images from the commercial equipment.  The new possibility of further analysis of this  problem showed up with the availability of a public database containing original raw  radio frequency (RF) signals. In particular, it appeared  that the original texture might contain  diagnostic information which could be modified in the typical image processing and which is more difficult  to perceive than the  details of  lesion shape/contour. In this paper a  detailed analysis of the lesion texture is conducted by means of the decision trees and  logistic regression. The decision trees turned out  useful mainly for selecting texture features to be used in the stepwise logistic regression. The RF signals database of 200 breast lesions  was used for testing the performance of the benign vs malignant lesion classifier. The Gray Level Cooccurrence Matrix (GLCM)  was calculated with the vertical/horizontal offset of up to five pixels. For each of these matrices six features were calculated resulting in a total of 210 features. Using these features a sufficient number of decision trees were generated to calculate pseudo-Receiver Operating Characteristics (ROCs). The outcome of this  process is a collection of generated trees for which the employed features are known. These features were then used for generating  generalized linear model by means of stepwise logistic regression. The analyzed regression  models included the coefficients of up-to-the second degree terms. The texture features were further completed by a single shape feature,  that is tumor circularity (TC). The automatic procedure for finding the exact mask of a lesion is also provided for the conditions when the acoustic shadowing makes it impossible to obtain the entire contour reliably and a half-contour has to be used. The selected logistic regression models gave  ROCs with the Area Under Curve (AUC) of up to 0.83 and the 95 \% confidence region (0.63 0.96). Analyzing classification results one comes to the conclusion that the tumor circularity, which is the most informative  among shape/contour features, is not essential against the background of textural features. The reported study shows that a relatively straightforward procedure can be employed  to obtain  benign vs malignant  classifier comparable with that originally used for the database of the raw RF signals and based on the more complicated segmentation of the parameter maps of homodyned K distribution.


2018 ◽  
Vol 8 (9) ◽  
pp. 1569 ◽  
Author(s):  
Shengbing Wu ◽  
Hongkun Jiang ◽  
Haiwei Shen ◽  
Ziyi Yang

In recent years, gene selection for cancer classification based on the expression of a small number of gene biomarkers has been the subject of much research in genetics and molecular biology. The successful identification of gene biomarkers will help in the classification of different types of cancer and improve the prediction accuracy. Recently, regularized logistic regression using the L 1 regularization has been successfully applied in high-dimensional cancer classification to tackle both the estimation of gene coefficients and the simultaneous performance of gene selection. However, the L 1 has a biased gene selection and dose not have the oracle property. To address these problems, we investigate L 1 / 2 regularized logistic regression for gene selection in cancer classification. Experimental results on three DNA microarray datasets demonstrate that our proposed method outperforms other commonly used sparse methods ( L 1 and L E N ) in terms of classification performance.


2013 ◽  
Vol 29 (7) ◽  
pp. 870-877 ◽  
Author(s):  
Jakramate Bootkrajang ◽  
Ata Kabán

NeuroImage ◽  
2010 ◽  
Vol 51 (2) ◽  
pp. 752-764 ◽  
Author(s):  
Srikanth Ryali ◽  
Kaustubh Supekar ◽  
Daniel A. Abrams ◽  
Vinod Menon

Now a day’s cancer has become a deathly disease due to the abnormal growth of the cell. Many researchers are working in this area for the early prediction of cancer. For the proper classification of cancer data, demands for the identification of proper set of genes by analyzing the genomic data. Most of the researchers used microarrays to identify the cancerous genomes. However, such kind of data is high dimensional where number of genes are more compared to samples. Also the data consists of many irrelevant features and noisy data. The classification technique deal with such kind of data influences the performance of algorithm. A popular classification algorithm (i.e., Logistic Regression) is considered in this work for gene classification. Regularization techniques like Lasso with L1 penalty, Ridge with L2 penalty, and hybrid Lasso with L1/2+2 penalty used to minimize irrelevant features and avoid overfitting. However, these methods are of sparse parametric and limits to linear data. Also methods have not produced promising performance when applied to high dimensional genome data. For solving these problems, this paper presents an Additive Sparse Logistic Regression with Additive Regularization (ASLR) method to discriminate linear and non-linear variables in gene classification. The results depicted that the proposed method proved to be the best-regularized method for classifying microarray data compared to standard methods


Author(s):  
Yashpal Jitarwal ◽  
Tabrej Ahamad Khan ◽  
Pawan Mangal

In earlier times fruits were sorted manually and it was very time consuming and laborious task. Human sorted the fruits of the basis of shape, size and color. Time taken by human to sort the fruits is very large therefore to reduce the time and to increase the accuracy, an automatic classification of fruits comes into existence.To improve this human inspection and reduce time required for fruit sorting an advance technique is developed that accepts information about fruits from their images, and is called as Image Processing Technique.


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