Small fibers, large impact: Quality of life in small-fiber neuropathy

2013 ◽  
Vol 49 (3) ◽  
pp. 329-336 ◽  
Author(s):  
Mayienne Bakkers ◽  
Catharina G. Faber ◽  
Janneke G.J. Hoeijmakers ◽  
Giuseppe Lauria ◽  
Ingemar S.J. Merkies
Keyword(s):  
Quality Of Life ◽  
Small Fiber Neuropathy ◽  
Large Impact ◽  
Small Fiber

scholarly journals Long-Time Course of Idiopathic Small Fiber Neuropathy

2018 ◽  
Vol 79 (3-4) ◽  
pp. 161-165 ◽  
Author(s):  
Pia Flossdorf ◽  
Walter F. Haupt ◽  
Anna Brunn ◽  
Martina Deckert ◽  
Gereon R. Fink ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Time Course ◽  
Benign Disease ◽  
Small Fiber Neuropathy ◽  
Disease Course ◽  
Peripheral Neuropathies ◽  
Small Fiber ◽  
Long Time ◽  
Large Fiber

Background: Small fiber neuropathy (SFN) is a challenging subtype of peripheral neuropathies. Once the diagnosis has been established, there is an uncertainty how SFN may progress, whether larger fibers will become involved over time, whether quality of life may be compromised, or whether repeated diagnostic workup in patients with unknown underlying cause may increase the yield of treatable causes of SFN. Methods: We evaluated 16 patients with documented long-time course of idiopathic SFN. Results: Clinical and electrophysiological course remained stable in 75% of the patients, while 25% SFN-patients developed large fiber neuropathies. Conclusions: Our data suggest that SFN represents a benign disease course in the majority of patients without severely limiting the quality of life.

Small Fiber Neuropathy

2019 ◽  
Vol 39 (05) ◽  
pp. 570-577 ◽  
Author(s):  
Lan Zhou
Keyword(s):  
Skin Biopsy ◽  
Lifestyle Modification ◽  
Specific Treatment ◽  
Small Fiber Neuropathy ◽  
Fiber Density ◽  
Small Fiber ◽  
Intraepidermal Nerve Fiber Density ◽  
Associated Conditions ◽  
Density Evaluation

AbstractSmall fiber neuropathy (SFN) is common, and can be associated with many medical conditions. The majority of the patients with SFN suffer from painful paresthesia which can negatively impact their quality of life. Skin biopsy with intraepidermal nerve fiber density evaluation is the gold standard diagnostic test. Autonomic function testing is useful when autonomic symptoms are present. Screening for associated conditions should be done in every patient, even when a known underlying associated condition is present, before the neuropathy evaluation. Etiology-specific treatment, lifestyle modification, and pain control are the key elements of SFN management. This article will review the clinical presentation, skin biopsy procedure, utility of diagnostic tests, associated conditions, management, and prognosis of SFN.

scholarly journals Quality of life in polyneuropathy: association with biomarkers of small fiber impairment

2015 ◽  
Vol 13 (1) ◽  
Author(s):  
Meng-Ting Lin ◽  
Lukas Jyuhn-Hsiarn Lee ◽  
Chi-Chao Chao ◽  
Sung-Tsang Hsieh
Keyword(s):  
Quality Of Life ◽  
Small Fiber

scholarly journals Current View of Diagnosing Small Fiber Neuropathy

2020 ◽  
pp. 1-23
Author(s):  
Lisette Raasing ◽  
Oscar Vogels ◽  
Marcel Veltkamp ◽  
Christiaan van Swol ◽  
Jan Grutters
Keyword(s):  
Small Fiber Neuropathy ◽  
Diagnostic Methods ◽  
Work Flow ◽  
Current View ◽  
C Fibers ◽  
Small Fiber ◽  
Sensory Changes ◽  
Diagnostic Work ◽  
Sensory Fibers

Small fiber neuropathy (SFN) is a disorder of the small myelinated Aδ-fibers and unmyelinated C-fibers [5, 6]. SFN might affect small sensory fibers, autonomic fibers or both, resulting in sensory changes, autonomic dysfunction or combined symptoms [7]. As a consequence, the symptoms are potentially numerous and have a large impact on quality of life [8]. Since diagnostic methods for SFN are numerous and its pathophysiology complex, this extensive review focusses on categorizing all aspects of SFN as disease and its diagnosis. In this review, sensitivity in combination with specificity of different diagnostic methods are described using the areas under the curve. In the end, a diagnostic work-flow is suggested based on different phenotypes of SFN.

scholarly journals The Impact of Female Pattern Hair Loss on Quality of Life

2019 ◽  
Vol 4 (3) ◽  
Keyword(s):  
Quality Of Life ◽  
Hair Loss ◽  
Statistical Tests ◽  
Large Impact ◽  
Life Questionnaire ◽  
Dermatology Clinic ◽  
Female Pattern Hair Loss ◽  
Co Morbidity ◽  
The Impact

Background: Female pattern hair loss (FPHL) is a non-scarring alopecia characterised by the progressive thinning of hair. Hair has an important role in determining one’s self-esteem, confidence and attractiveness. Hence, hair loss can heavily affect patients’ quality of life (QoL). This study aims to assess the impact FPHL has on QoL in order to help improve patient management. Methods: Twenty-two patients presenting to an outpatient dermatology clinic in Wolverhampton, UK, took part in this study. The impact of FPHL on QoL was measured using two questionnaires: the women’s androgenic alopecia quality of life questionnaire (Waa-QoL) and the dermatology life quality index (DLQI). Participants were screened for psychological co-morbidity using the hospital anxiety and depression scale (HADS). Statistical tests used were Spearman’s rank correlation, Mann-Whitney U and Kruskal Wallis tests. Results: FPHL had a large impact on QoL. Patients who were younger or had a longer duration of disease had a significantly lower QoL (p<0.05). Furthermore, patient with a diagnosed mental health illness had a significantly lower QoL than those without (p<0.05). Conclusions: FPHL has a significant and detrimental effect on patients’ QoL. This study identifies several factors that are associated with a worse QoL outcome. This recognises groups of patients which could be targeted for more intensive intervention. Recognising the large impact on QoL, FPHL patients may benefit from a more holistic management with psychological interventions and a greater emphasis on improving QoL.

scholarly journals ACNE;

2019 ◽  
Vol 26 (02) ◽  
Author(s):  
Naima Luqman ◽  
Summaira Hassan ◽  
Niaz Maqsood ◽  
Wajid Ali Akhunzada
Keyword(s):  
Quality Of Life ◽  
Dermatology Life Quality Index ◽  
Outcome Measure ◽  
Life Quality ◽  
Descriptive Study ◽  
Large Impact ◽  
Age Group ◽  
Medical College ◽  
The Impact

Objectives: To determine the impact of acne on the quality of life of the patients. Study Design: A descriptive study. Place & Duration of Study: The study was conducted in the Department of Dermatology, Bahawal Victoria Hospital & Quaid-e-Azam Medical College, Bahawalpur April, 2017 to June, 2017. Subjects & Methods: The sample consisted of 50 out-patients (41 Females, 9 Males) with Acne. They were interviewed and results were analysed from the entries in a Performa. Dermatology Life Quality Index (DLQI) was administered as outcome measure. Results: Among 50 patients, there were 41(82%) were female, 27(54%) were 21-25 years age group, 44(88%) belonged to urban area, 28(56%) single and 25(50%) students. In assessing the quality of life, 34(68%) patients had extremely large impact on their quality of life after Acne. Conclusions: We concluded that acne had an extremely large impact on quality of life of majority of patients. Management of acne must include the impact of acne on the patient's quality of life.

scholarly journals A Unique Case for Spinal Cord Stimulation: Successful Treatment of Small Fiber Neuropathy Pain Using Multiple Spinal Cord Stimulators

2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Maxim Eckmann ◽  
Alexander Papanastassiou ◽  
Mark Awad
Keyword(s):  
Spinal Cord ◽  
Neuropathic Pain ◽  
Case Report ◽  
Poor Quality ◽  
Small Fiber Neuropathy ◽  
Entire Body ◽  
Full Time ◽  
Unique Case ◽  
Small Fiber

Spinal cord stimulators have commonly been used to treat multiple pain conditions. This case report represents a unique case of using multiple spinal cord stimulators for widespread small fiber neuropathy pain. This case report concerns patient JJ who first presented with generalized neuropathic pain. His pain was an intermittent burning, stinging quality that originally focused in both of his feet and progressed to include his legs and arms and eventually involved his entire body. The pain would last moments to hours at least daily. He reported a poor quality of life. He was diagnosed with small fiber neuropathy with anhydrosis, suggestive of idiopathic erythromelalgia. He had a spinal cord stimulator trial involving both cervical and lower thoracic percutaneous leads. After two spinal cord stimulators were implanted, the patient began to report an improvement in pain. The patient continues to report excellent pain relief. The patient uses the stimulator intermittently as needed, in an abortive fashion for pain flares. The patient is very pleased and has increased his activity. He now attends graduate school full time. This case report hopes to illustrate a unique use of multiple spinal cord stimulators in treating widespread neuropathic pain caused by small fiber neuropathy.

Self-Compassion and Quality of Life in Adults Who Stutter

2020 ◽  
Vol 29 (4) ◽  
pp. 2097-2108
Author(s):  
Robyn L. Croft ◽  
Courtney T. Byrd
Keyword(s):  
Quality Of Life ◽  
Social Connectedness ◽  
The Self ◽  
Future Research ◽  
Self Compassion ◽  
Adults Who Stutter ◽  
And Gender ◽  
Relationship Of ◽  
The Impact

Purpose The purpose of this study was to identify levels of self-compassion in adults who do and do not stutter and to determine whether self-compassion predicts the impact of stuttering on quality of life in adults who stutter. Method Participants included 140 adults who do and do not stutter matched for age and gender. All participants completed the Self-Compassion Scale. Adults who stutter also completed the Overall Assessment of the Speaker's Experience of Stuttering. Data were analyzed for self-compassion differences between and within adults who do and do not stutter and to predict self-compassion on quality of life in adults who stutter. Results Adults who do and do not stutter exhibited no significant differences in total self-compassion, regardless of participant gender. A simple linear regression of the total self-compassion score and total Overall Assessment of the Speaker's Experience of Stuttering score showed a significant, negative linear relationship of self-compassion predicting the impact of stuttering on quality of life. Conclusions Data suggest that higher levels of self-kindness, mindfulness, and social connectedness (i.e., self-compassion) are related to reduced negative reactions to stuttering, an increased participation in daily communication situations, and an improved overall quality of life. Future research should replicate current findings and identify moderators of the self-compassion–quality of life relationship.

Misophonia: An Evidence-Based Case Report

2020 ◽  
Vol 29 (4) ◽  
pp. 685-690
Author(s):  
C. S. Vanaja ◽  
Miriam Soni Abigail
Keyword(s):  
Quality Of Life ◽  
Case Report ◽  
Case History ◽  
Pure Tone ◽  
Physiological Responses ◽  
Evidence Based ◽  
Management Option ◽  
Pure Tone Audiogram

Purpose Misophonia is a sound tolerance disorder condition in certain sounds that trigger intense emotional or physiological responses. While some persons may experience misophonia, a few patients suffer from misophonia. However, there is a dearth of literature on audiological assessment and management of persons with misophonia. The purpose of this report is to discuss the assessment of misophonia and highlight the management option that helped a patient with misophonia. Method A case study of a 26-year-old woman with the complaint of decreased tolerance to specific sounds affecting quality of life is reported. Audiological assessment differentiated misophonia from hyperacusis. Management included retraining counseling as well as desensitization and habituation therapy based on the principles described by P. J. Jastreboff and Jastreboff (2014). A misophonia questionnaire was administered at regular intervals to monitor the effectiveness of therapy. Results A detailed case history and audiological evaluations including pure-tone audiogram and Johnson Hyperacusis Index revealed the presence of misophonia. The patient benefitted from intervention, and the scores of the misophonia questionnaire indicated a decrease in the severity of the problem. Conclusions It is important to differentially diagnose misophonia and hyperacusis in persons with sound tolerance disorders. Retraining counseling as well as desensitization and habituation therapy can help patients who suffer from misophonia.

Quality of Life of Youth With Hearing Loss

ASHA Leader ◽  
2010 ◽  
Vol 15 (15) ◽  
pp. 5-6
Author(s):  
Anne Skalicky ◽  
Brenda Schick ◽  
Donald Patrick
Keyword(s):  
Quality Of Life ◽  
Hearing Loss
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