scholarly journals Changes in Cardiometabolic Risk Factors Before and After Gestational Diabetes: A Prospective Life‐Course Analysis in CARDIA Women

Obesity ◽  
2020 ◽  
Vol 28 (8) ◽  
pp. 1397-1404
Author(s):  
Janet M. Catov ◽  
Baiyang Sun ◽  
Marnie Bertolet ◽  
Gabrielle G. Snyder ◽  
Cora E. Lewis ◽  
...  
2013 ◽  
Vol 289 (4) ◽  
pp. 787-793 ◽  
Author(s):  
Baris Akinci ◽  
Aygul Celtik ◽  
Sunay Tunali ◽  
Sinan Genc ◽  
Faize Yuksel ◽  
...  

2020 ◽  
Vol 9 (15) ◽  
Author(s):  
Baiyang Sun ◽  
Marnie Bertolet ◽  
Maria M. Brooks ◽  
Carl A. Hubel ◽  
Cora E. Lewis ◽  
...  

Obesity ◽  
2012 ◽  
Vol 20 (4) ◽  
pp. 886-890 ◽  
Author(s):  
Antony D. Karelis ◽  
Rémi Rabasa-Lhoret ◽  
Roseline Pompilus ◽  
Virginie Messier ◽  
Irene Strychar ◽  
...  

BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S246-S247
Author(s):  
Nicholas Dodough ◽  
Jaspreet Phull ◽  
Jaswant Singh ◽  
Jackie Sendell

AimsTo explore the impact of the March 2020 lockdown restrictions on the cardiometabolic risk factors of male forensic and rehabilitation inpatients in one NHS trust in the United Kingdom.MethodRetrospective data from September 2019 to September 2020 (six months before and after the 23 March 2020 lockdown) was collected by evaluating the health records of male patients in a low secure forensic ward and two rehabilitation units.ResultThe number of patients with BMI values within the study period was 34 while the number of patients with blood results was 26. This study showed that the average BMI six months before the start of the March lockdown was 29.8 kg/m2 while the average BMI at the end of six months after the lockdown was 31.8 kg/m2.The results from the 6-month interval before the March 2020 lockdown (M = 0, SD = 0) and the 6- month interval after the March 2020 lockdown (M = 0.9, SD = 4.16) indicate that the March 2020 lockdown resulted in an increase of BMI, t (5) = 2.42, P = 0.036. The result is significant at p < 0.058.8% of patients had an increase in their doses of antihypertensive agents after the lockdown whereas no patients had an increase of dose before the lockdown. 7.7% of patients had an HBA1c of more than 48 mmol/L after the lockdown compared to 3.8% before the lockdown. The serum triglycerides and total cholesterol levels also increased after the lockdown with an average increase of 0.17 mmol/L and 0.25 mmol/L respectively. The average serum HDL levels decreased after the lockdown with an average decrease of 0.06 mmol/L.ConclusionThere appears to be a positive correlation between the onset of the March 2020 lockdown and an increase of BMI, worsening of blood pressure, glycemic control and lipid metabolism.Limitations (1)Waist circumference was not measured during the study period preventing us from examining all of the features of metabolic syndrome.(2)This study did not look at the levels of physical activity (such as access to section 17 leave) and dietary habits before and after the March 2020 lockdown which may explain the results found.RecommendationsTo raise metabolic awareness of the impact of the lockdown restrictions on cardiometabolic risk in people with SMI and the general public.


Author(s):  
Sanem Kayhan ◽  
Nazli Gulsoy Kirnap ◽  
Mercan Tastemur

Abstract. Vitamin B12 deficiency may have indirect cardiovascular effects in addition to hematological and neuropsychiatric symptoms. It was shown that the monocyte count-to-high density lipoprotein cholesterol (HDL-C) ratio (MHR) is a novel cardiovascular marker. In this study, the aim was to evaluate whether MHR was high in patients with vitamin B12 deficiency and its relationship with cardiometabolic risk factors. The study included 128 patients diagnosed with vitamin B12 deficiency and 93 healthy controls. Patients with vitamin B12 deficiency had significantly higher systolic blood pressure (SBP), diastolic blood pressure (DBP), MHR, C-reactive protein (CRP) and uric acid levels compared with the controls (median 139 vs 115 mmHg, p < 0.001; 80 vs 70 mmHg, p < 0.001; 14.2 vs 9.5, p < 0.001; 10.2 vs 4 mg/dl p < 0.001; 6.68 vs 4.8 mg/dl, p < 0.001 respectively). The prevalence of left ventricular hypertrophy was higher in vitamin B12 deficiency group (43.8%) than the control group (8.6%) (p < 0.001). In vitamin B12 deficiency group, a positive correlation was detected between MHR and SBP, CRP and uric acid (p < 0.001 r:0.34, p < 0.001 r:0.30, p < 0.001 r:0.5, respectively) and a significant negative correlation was detected between MHR and T-CHOL, LDL, HDL and B12 (p < 0.001 r: −0.39, p < 0.001 r: −0.34, p < 0.001 r: −0.57, p < 0.04 r: −0.17, respectively). MHR was high in vitamin B12 deficiency group, and correlated with the cardiometabolic risk factors in this group, which were SBP, CRP, uric acid and HDL. In conclusion, MRH, which can be easily calculated in clinical practice, can be a useful marker to assess cardiovascular risk in patients with vitamin B12 deficiency.


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