Self-report of current and prior antiretroviral drug use in comparison to the medical record among HIV-infected patients receiving primary HIV care

AbstractContradictory data have been reported concerning neuropsychiatric side effects of the first-line antiretroviral drug dolutegravir, which may be partly due to lack of control groups or psychiatric assessment tools. Using validated self-report questionnaires, we compared mood and anxiety (DASS-42), impulsivity (BIS-11), and substance use (MATE-Q) between dolutegravir-treated and dolutegravir-naive people living with HIV (PLHIV). We analyzed 194, mostly male, PLHIV on long-term treatment of whom 82/194 (42.3%) used dolutegravir for a median (IQR) of 280 (258) days. Overall, 51/194 (26.3%) participants reported DASS-42 scores above the normal cut-off, 27/194 (13.5%) were classified as highly impulsive, and 58/194 (29.9%) regularly used recreational drugs. Regular substance use was positively associated with depression (p = 0.012) and stress scores (p = 0.045). We observed no differences between dolutegravir-treated and dolutegravir-naive PLHIV. Our data show that depressed and anxious moods and impulsivity are common in PLHIV and associate with substance use and not with dolutegravir use.

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Use of illicit drugs by adolescents and young adults of an urban settlement in Brazil

Revista da Associação Médica Brasileira ◽

10.1590/1806-9282.64.02.114 ◽

2018 ◽

Vol 64 (2) ◽

pp. 114-118

Author(s):

Rafael Alves Guimarães ◽

Márcia Maria de Souza ◽

Karlla Antonieta Amorim Caetano ◽

Sheila Araujo Teles ◽

Marcos André de Matos

Keyword(s):

Young Adults ◽

Drug Use ◽

Illicit Drugs ◽

Illicit Drug ◽

Illicit Drug Use ◽

Self Report ◽

Adolescents And Young Adults ◽

Cross Sectional ◽

Urban Settlement ◽

Factors Associated

Summary Objective: To estimate the prevalence and factors associated with illicit drug use by adolescents and young adults of a formal urban settlement. Method: Cross-sectional study including adolescents and young adults 12-24 years of an urban settlement in the Midwest Region of Brazil. Data were collected using a structured questionnaire and analyzed using Stata, version 12.0. We used Poisson regression model to estimate the factors associated with illicit drug use. Results: Of the total participants (n=105), 27.6% (95CI 20.0-36.9%) had used illicit drugs such as marijuana, cocaine, crack, LSD and inhalants. The consumption of these substances was associated with male gender, use of body piercing and/or tattoos, licit drug use and self-report of signs and/or symptoms of sexually transmitted infections. Conclusion: High prevalence of illicit drug use was found in the individuals investigated, ratifying the presence of risk factors to the vulnerability of the settlers to use these substances in the urban settlement population.

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Do Self-Report Studies of Drug Use Really Give Dependable Results?

Canadian Journal of Criminology ◽

10.3138/cjcrim.23.1.83 ◽

1981 ◽

Vol 23 (1) ◽

pp. 83-92 ◽

Cited By ~ 2

Author(s):

Reginald G. Smart ◽

George K. Jarvis

Keyword(s):

Drug Use ◽

Self Report

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Potential Influences of the COVID-19 Pandemic on Drug Use and HIV Care Among People Living with HIV and Substance Use Disorders: Experience from a Pilot mHealth Intervention

AIDS and Behavior ◽

10.1007/s10461-020-02976-1 ◽

2020 ◽

Author(s):

Karli R. Hochstatter ◽

Wajiha Z. Akhtar ◽

Sarah Dietz ◽

Klaren Pe-Romashko ◽

David H. Gustafson ◽

...

Keyword(s):

Substance Use ◽

Drug Use ◽

Substance Use Disorders ◽

Hiv Care ◽

People Living With Hiv ◽

Mhealth Intervention ◽

Living With Hiv

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1310. The Impact of Recent Incarceration on Post-Release HIV Linkage to Care and Risk-Taking Behaviors in the Setting of Enhanced Linkage to Care Policies in Florida

Open Forum Infectious Diseases ◽

10.1093/ofid/ofz360.1173 ◽

2019 ◽

Vol 6 (Supplement_2) ◽

pp. S472-S473

Author(s):

Greg Matthew E Teo ◽

Suraj Nagaraj ◽

Nisha Sunku ◽

Sadaf Aslam ◽

Rahul Mhaskar ◽

...

Keyword(s):

High Risk ◽

Risk Behaviors ◽

Barriers To Care ◽

Linkage To Care ◽

The United States ◽

Self Report ◽

Hiv Care ◽

High Risk Behaviors ◽

Persons Living With Hiv ◽

The Impact

Abstract Background The United States has the largest incarcerated population in the world with 6.61 million adults in 2016.1 While incarceration is a known risk factor for difficulties in linkage to care2–3 and adverse health outcomes4–6, little is published on post-release incarcerated persons living with HIV (PLWH) in Florida. Methods Data were acquired from the Florida Cohort, an ongoing, longitudinal, cross-sectional study of PLWH recruited across HIV clinics in the state of Florida, from 2014 to 2018. Chi-square and multiple regression analyses correlated recent incarceration (within last 12 months) with demographics, HIV care adherence, perceived barriers to care, and self-reported high-risk behaviors. Results Of 936 participants, 6.4% (n = 60) reported recent incarceration within the last 12 months. Those recently incarcerated were more likely to report missing at least one appointment in the last 6 months (46.7% vs. 22.2%; P < 0.0001), to have an excessively long travel time ( >60 minutes) to a HIV provider (34.5% vs. 16.6%, P = 0.002; OR 2.66 [95% CI: 1.20–5.92]), and to lack reliable transportation (70% vs. 47.5%, P = 0.0007; OR 1.70 [95% CI: 0.82–3.52]) Those not recently incarcerated reported having completed a high school education (OR: 0.69 [95% CI: 0.5–0.97]) and stated they “never missed an appointment” (OR: 0.42 [95% CI: 0.22–0.81]). Recently incarcerated PLWH also had higher occurrence of high-risk behaviors such as receiving (40.4% vs. 8.7%; P = 0.001) or providing (30.4% vs. 10.4%; P = 0.000) money or drugs for sex, having used IV drugs (15% vs. 4%; P = 0.001), and not using condoms during exchange of drugs for sex (OR: 9.43 [95% CI: 3.78–23.52]). Conclusion Recently incarcerated PLWH continue to have significant geographical and logistical barriers to care and self-report more high-risk behaviors than nonincarcerated peers. Enhanced case management and telehealth services may be useful in linkage to care when PLWH transition from correctional to community healthcare systems in the Florida setting. Disclosures All authors: No reported disclosures.

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Drug use, self report and urinalysis

Drug and Alcohol Dependence ◽

10.1016/s0376-8716(99)00066-6 ◽

2000 ◽

Vol 58 (1-2) ◽

pp. 111-116 ◽

Cited By ~ 32

Author(s):

Bridget Kilpatrick ◽

Mary Howlett ◽

Philip Sedgwick ◽

A.Hamid Ghodse

Keyword(s):

Drug Use ◽

Self Report

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Reassessing the Need for Urinalysis as a Validation Technique

Journal of Drug Issues ◽

10.1177/002204260003000205 ◽

2000 ◽

Vol 30 (2) ◽

pp. 323-334 ◽

Cited By ~ 24

Author(s):

George S. Yacoubian

Keyword(s):

Drug Abuse ◽

Drug Use ◽

Past Research ◽

Self Report ◽

Strong Correlations ◽

Heroin Use ◽

Report Data ◽

Validation Technique ◽

Self Report Data ◽

Over Time

Urinalysis is utilized routinely as a tool to validate self-reported drug use. Past research has been inconclusive, however, in confirming strong correlations between urinalysis and self-reported drug use. In the current study, correlation estimates for cocaine and heroin use are derived from adult arrestees surveyed through the Arrestee Drug Abuse Monitoring (ADAM) Program between 1990 and 1997. While the strength of agreement between urinalysis and self-report data varies by both substance and jurisdiction, correlation estimates are consistent over time. These findings suggest that the need for urinalysis should be reassessed.

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Ecstasy and Drug Consumption Patterns: A Canadian Rave Population Study

The Canadian Journal of Psychiatry ◽

10.1177/070674370204700606 ◽

2002 ◽

Vol 47 (6) ◽

pp. 546-551 ◽

Cited By ~ 66

Author(s):

Samantha R Gross ◽

Sean P Barrett ◽

John S Shestowsky ◽

Robert O Pihl

Keyword(s):

Drug Use ◽

Rank Order ◽

Drug Consumption ◽

Consumption Patterns ◽

Self Report ◽

Cumulative Number ◽

Gamma Hydroxybutyrate ◽

Early Use ◽

Amphetamine Use ◽

The City

Objective: This study investigates the drug consumption patterns of a sample of rave attendees in the city of Montreal, Quebec, and seeks to identify the prevalence of 3,4-methylendioxymethamphetamine (MDMA) and other drug use in this population. Method: We administered a self-report questionnaire to 210 respondents. For various licit and illicit substances, participants reported their age of first use, number of lifetime uses, and usage in the previous 30 days. Results: We found a significant rank order for the sequence of first use: 1) alcohol, 2) nicotine, 3) cannabis, 4) LSD, 5) psilocybin, 6) amphetamine, 7) cocaine, 8) MDMA, 9) gamma-hydroxybutyrate (GHB), 10) ephedrine, 11) ketamine. Alcohol and cannabis were the most commonly used substances, both in cumulative number of lifetime uses and in usage in the preceding 30 days. MDMA and amphetamine were also notable as the next 2 most popular drugs for use in the preceding 30 days and in terms of those who had tried the drugs at least once. We identified a progressive rank order of experimentation, with early alcohol or cannabis use (or both) associated with the early use of all other drugs tried by more than 25% of the sample. We found MDMA and amphetamine use to be prevalent, as was general experimentation with all drugs studied, other than heroin. Conclusion: Drug consumption levels were substantial in this “rave” population, particularly with respect to recent use of MDMA, amphetamine, cannabis, and alcohol. Results also indicate that the sequence of drug experimentation in this population follows an identifiable pattern.

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