A covariate-adjustment regression model approach to noninferiority margin definition

2010 ◽  
Vol 29 (10) ◽  
pp. 1107-1113 ◽  
Author(s):  
Lei Nie ◽  
Guoxing Soon
2011 ◽  
Vol 11 (1) ◽  
pp. 125
Author(s):  
Glen A. Larsen, Jr. ◽  
Gregory D. Wozniak

A discrete regression model (DRM) approach to timing the asset class markets for stocks, bonds, and cash in active asset allocation is presented. The technique involves investing in the asset class whose return is predicted to exceed the other asset class return after observing a sequential signal of estimated probabilities. The empirical results show that the DRM approach provides enhanced portfolio performance when compared to more passive fixed-weight portfolio strategies.


2020 ◽  
pp. 002580242097701
Author(s):  
Tobias MR Houlton ◽  
Nicolene Jooste ◽  
Maryna Steyn

Average facial soft-tissue thickness (FSTT) databanks are continuously developed and applied within craniofacial identification. This study considered and tested a subject-specific regression model alternative for estimating the FSTT values for oral midline landmarks using skeletal projection measurements. Measurements were taken from cone-beam computed tomography scans of 100 South African individuals (60 male, 40 female; Mage = 35 years). Regression equations incorporating sex categories were generated. This significantly improved the goodness-of-fit ( r2-value). Validation tests compared the constructed regression models with mean FSTT data collected from this study, existing South African FSTT data, a universal total weighted mean approach with pooled demographic data and collection techniques and a regression model approach that uses bizygomatic width and maximum cranial breadth dimensions. The generated regression equations demonstrated individualised results, presenting a total mean inaccuracy (TMI) of 1.53 mm using dental projection measurements and 1.55 mm using cemento-enamel junction projection measurements. These slightly outperformed most tested mean models (TMI ranged from 1.42 to 4.43 mm), and substantially outperformed the pre-existing regression model approach (TMI = 5.12 mm). The newly devised regressions offer a subject-specific solution to FSTT estimation within a South African population. A continued development in sample size and validation testing may help substantiate its application within craniofacial identification.


Author(s):  
Cippy Ardian Tyasto ◽  
Elly Sapto Utomo

In this study author will analyze the effect of portfolio investment placements on achieving BPJS Ketenagakerjaan surpluses with the linear regression model approach. In conducting this research, the author used the measurement methods of Standard Deviation. Historical Simulation and Variance Covariance. The timeframe used in this study began from 2014 to 2018. This study was to find out how much effect the placement of portfolio investment on the achievement of net income / surpluses on BPJS Ketenagakerjaan and what instruments were most influential in the period 2014 to 2018.


2020 ◽  
Vol 20 (23) ◽  
pp. 15401-15426
Author(s):  
Shuo Wang ◽  
Jason Blake Cohen ◽  
Chuyong Lin ◽  
Weizhi Deng

Abstract. Proper quantification of the aerosol vertical height is essential to constrain the atmospheric distribution and lifetime of aerosols, as well as their impact on the environment. We use globally distributed, daily averaged measurements of aerosol stereo heights of fire aerosols from the Multi-angle Imaging SpectroRadiometer (MISR) to understand the aerosol distribution. We also connect these results with a simple plume rise model and a new multi-linear regression model approach based on daily measurements of NO2 from OMI and CO from MOPITT to understand and model the global aerosol vertical height profile over biomass burning regions. First, plumes associated with the local dry-burning season at midlatitudes to high latitudes frequently have a substantial fraction lofted into the free troposphere and in some cases even the stratosphere. Second, plumes mainly associated with less-polluted regions in developing countries and heavily forested areas tend to stay closer to the ground, although they are not always uniformly distributed throughout the boundary layer. Third, plumes associated with more serious loadings of pollution (such as in Africa, Southeast Asia and northeast China) tend to have a substantial amount of smoke transported uniformly through the planetary boundary layer and up to around 3 km. Fourth, the regression model approach yields a better ability to reproduce the measured heights compared to the plume rise model approach. This improvement is based on a removal of the negative bias observed from the plume model approach, as well as a better ability to work under more heavily polluted conditions. However, over many regions, both approaches fail, requiring deeper work to understand the physical, chemical and dynamical reasons underlying the failure over these regions.


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