scholarly journals VP35.19: Can fractional limb volume improve the prediction of birthweight in suspected SGA fetuses?

2021 ◽  
Vol 58 (S1) ◽  
pp. 89-312
Author(s):  
E. Meler ◽  
D. Boada Diaz ◽  
J. Martinez ◽  
A. Peguero ◽  
F. Figueras
Keyword(s):  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Linda Paternò ◽  
Michele Ibrahimi ◽  
Elisa Rosini ◽  
Giuseppe Menfi ◽  
Vito Monaco ◽  
...  

AbstractThis study constitutes the first attempt to systematically quantify residual limb volume fluctuations in transfemoral amputees. The study was carried out on 24 amputees to investigate variations due to prosthesis doffing, physical activity, and testing time. A proper experimental set-up was designed, including a 3D optical scanner to improve precision and acceptability by amputees. The first test session aimed at measuring residual limb volume at 7 time-points, with 10 min intervals, after prosthesis doffing. This allowed for evaluating the time required for volume stabilization after prosthesis removal, for each amputee. In subsequent sessions, 16 residual limb scans in a day for each amputee were captured to evaluate volume fluctuations due to prosthesis removal and physical activity, in two times per day (morning and afternoon). These measurements were repeated in three different days, a week apart from each other, for a total of 48 scans for each amputee. Volume fluctuations over time after prosthesis doffing showed a two-term decay exponential trend (R2 = 0.97), with the highest variation in the initial 10 min and an average stabilization time of 30 min. A statistically significant increase in residual limb volume following both prosthesis removal and physical activity was verified. No differences were observed between measures collected in the morning and in the afternoon.Clinical Trials.gov ID: NCT04709367.



2019 ◽  
Vol 17 (3) ◽  
pp. 301-307 ◽  
Author(s):  
Christopher J. Coroneos ◽  
Franklin C. Wong ◽  
Sarah M. DeSnyder ◽  
Simona F. Shaitelman ◽  
Mark V. Schaverien


1989 ◽  
Vol 10 (1) ◽  
pp. 75-79 ◽  
Author(s):  
L H Cheah ◽  
A Parkin ◽  
P Gilson ◽  
S Elliot ◽  
A J Hall


Author(s):  
Jonathan G. Steller ◽  
Diane Gumina ◽  
Camille Driver ◽  
Claire Palmer ◽  
Laura D. Brown ◽  
...  




2021 ◽  
Author(s):  
Mei Rosemary Fu ◽  
Deborah Axelrod ◽  
Amber A Guth ◽  
Joan Scagliola ◽  
Kavita Rampertaap ◽  
...  

BACKGROUND The-Optimal-Lymph-Flow is a patient-centered, web-and-mobile-based mHealth system that delivers safe, easy and feasible digital therapy of lymphatic exercises and limb mobility exercises. The purpose of this randomized clinical trial (RCT) was to evaluate the effectiveness of the web-and-mobile-based The-Optimal-Lymph-Flow system for managing chronic pain and symptoms related to lymphedema. OBJECTIVE The primary objective of this study was to determine the effectiveness of the web-and-mobile-based The-Optimal-Lymph-Flow system for managing chronic pain, aching, soreness, and tenderness among breast cancer survivors and quality of life related to pain. The secondary objective was to evaluate the effectiveness of the web-and-mobile-based The-Optimal-Lymph-Flow system for managing symptoms related to lymph fluid accumulation, limb volume differences, and body mass index (BMI). METHODS A parallel randomized controlled trial (RCT) with a control-experimental, pre- and post-test, repeated-measures design. A total of 120 patients were recruited and randomized according to pain with 1:1 ratio into either Arm Precaution (AP) control focusing on limb mobility and protection or The-Optimal-Lymph flow (TOLF) intervention focusing promoting lymph flow and limb mobility. Trial outcomes were evaluated at baseline and week 12 post intervention. Descriptive statistics, Fisher’s Exact tests, Wilcoxon rank-sum tests, t-test, and generalized linear mixed-effects models were performed for data analysis. RESULTS At the study endpoint of week 12 post intervention, significantly fewer patients in the TOLF intervention group compared to AP control group reported chronic pain (49% vs. 71%; OR=0.39, CI=[0.17, 0.90], p=0.021). Patients in TOLF intervention group were significantly more likely to experience a complete reduction in chronic pain (50% vs 22%; OR=3.56, CI = [1.39, 9.76], p=0.005), and soreness (43% vs 22%; OR=2.60, CI = [1.03, 6.81], p=0.034). Significantly lower median severity scores were found in TOLF group for chronic pain (〖Med〗_LE=0, IQR=0-1 vs 〖Med〗_AP=1, IQR=0-2; p=0.024) and general bodily pain (〖Med〗_LE=1, IQR=0-1.5 vs 〖Med〗_AP=1, IQR=1-3; p=0.040). Compared to AP control, significantly fewer patients in TOLF group reported arm/hand swelling (p=0.038); heaviness (p=0.027), redness (p=0.033), limited movement in shoulder (p=0.015) and arm (p=0,025). No significant differences between TOLF and AP groups were found in complete reduction of aching and tenderness, mean numbers of lymphedema symptom reported, > 5% limb volume differences, and BMI. CONCLUSIONS TOLF intervention had significant benefits for breast cancer survivors to manage chronic pain, soreness, general bodily pain, limb swelling, heaviness, and impaired limb mobility. TOLF intervention resulted in a 13% reduction in proportions of patients who took pain medications compared to AP group which had a 5% increase. A 12% reduction in proportions of patients with > 5% limb volume differences were found in the TOLF group while a 5% increase in the AP group. Taking together, TOLF intervention can be a better choice for breast cancer survivors to reduce chronic pain and limb volume. CLINICALTRIAL US Clinicaltrials.gov NCT02462226, https://clinicaltrials.gov/ct2/show/NCT02462226



2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Rianne Kofman ◽  
Raoul E Winter ◽  
Cornelis H Emmelot ◽  
Jan HB Geertzen ◽  
Pieter U Dijkstra


2021 ◽  
Author(s):  
Xining Wu ◽  
Zihan Niu ◽  
Zhonghui Xu ◽  
Yuxin Jiang ◽  
Yixiu Zhang ◽  
...  

Abstract Background: Accurate estimation of fetal weight is important for prenatal care and for detection of fetal growth abnormalities. Prediction of fetal weight entails the indirect measurement of fetal biometry by ultrasound that is then introduced into formulae to calculate the estimated fetal weight. The aim of our study was to evaluate the accuracy of the automated three-dimensional(3D) fractional limb volume model to predict fetal weight in the third trimester.Methods: Prospective 2D and 3D ultrasonography were performed among women with singleton pregnancies 7 days before delivery to obtain 2D data, including fetal biparietal diameter, abdominal circumference and femur length, as well as 3D data, including the fractional arm volume (AVol) and fractional thigh volume (TVol). The fetal weight was estimated using the 2D model and the 3D fractional limb volume model respectively. Percentage error = (estimated fetal weight - actual birth weight) ÷ actual birth weight × 100. Systematic errors (accuracy) were evaluated as the mean percentage error (MPE). Random errors (precision) were calculated as±1 SD of percentage error.Results: Ultrasound examination was performed on 56 fetuses at 39.6 ± 1.4 weeks gestation. The average birth weight of the newborns was 3393 ± 530 g. The average fetal weight estimated by the 2D model was 3478 ± 467 g, and the MPE was 3.2 ± 8.9. The average fetal weights estimated by AVol and TVol of the 3D model were 3268 ± 467 g and 3250 ± 485 g, respectively, and the MPEs were -3.3 ± 6.6 and -3.9 ± 6.1, respectively. For the 3D TVol model, the proportion of fetuses with estimated error ≤ 5% was significantly higher than that of the 2D model (55.4% vs. 33.9%, p < 0.05). For fetuses with a birth weight < 3500 g, the accuracy of the AVol and TVol models were better than the 2D model (-0.8 vs. 7.0 and -2.8 vs. 7.0, both p < 0.05). Moreover, for these fetus, the proportions of estimated error ≤ 5% of the AVol and TVol models were 58.1% and 64.5%, respectively, significantly higher than that of the 2D model (19.4%) (both p < 0.05). The consistency of different examiners measuring fetal AVol and TVol were satisfactory,with the intraclass correlation coefficients of 0.921 and 0.963, respectively.Conclusion: In this cohort,the automated 3D fractional limb volume model improves the accuracy of weight estimation in most third-trimester fetuses. In particular, the 3D model estimation accuracy for fetuses with weight < 3500 g is significantly higher than that of the traditional 2D model.



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