Cholesterol Esterification and Net Mass Transfer of Cholesterylesters and Triglycerides in Plasma From Healthy Subjects and Hyperlipidemic Coronary Heart Disease Patients

1988 ◽  
pp. 231-237 ◽  
Author(s):  
A. Van Tol ◽  
L. M. Scheek ◽  
J. E. M. Groener
Keyword(s):  
Mass Transfer ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Healthy Subjects ◽  
Cholesterol Esterification

Assessment of the Type D personality distress in coronary heart disease patients and healthy subjects in Spain

2019 ◽  
Vol 142 ◽  
pp. 301-309
Author(s):  
Anton Aluja ◽  
Olga Malas ◽  
Ignacio Lucas ◽  
Fernando Worner ◽  
Ramon Bascompte
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Healthy Subjects ◽  
Type D Personality ◽  
Type D

Abstract 17312: Amyloid-β (1-40) and the Risk of Death from Cardiovascular Causes in Patients with Coronary Heart Disease

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Kimon Stamatelopoulos ◽  
Dirk Sibbing ◽  
Loukianos S Rallidis ◽  
Georgios Georgiopoulos ◽  
Dimitrios Stakos ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Arterial Stiffness ◽  
Healthy Subjects ◽  
Subclinical Atherosclerosis ◽  
Amyloid Β ◽  
High Sensitivity ◽  
Left Ventricular Ejection ◽  
Clinical Value ◽  
Prospective Cohorts

Introduction: Investigation of the clinical value of biologic pathways that are involved in pathogenesis of atherosclerotic disease is essential for identification of novel therapeutic targets and improvement of cardiovascular risk stratification. Hypothesis: To determine the clinical value of amyloid-β 1-40 (Aβ40) measurement in predicting cardiovascular (CV) mortality in patients with coronary heart disease (CHD) and arterial stiffness progression in young healthy subjects. Methods: Aβ40 was retrospectively measured in blood samples collected from three independent prospective cohorts and two case-control cohorts (total n=1464). Major adverse CV events (MACE) were assessed in the two prospective cohorts (n=877) followed for a median of 4.4 years. Arterial stiffness was evaluated at baseline and after a 5-year follow-up period (n=107) in young healthy subjects. The primary endpoint was the predictive value of Aβ40 for CV mortality and outcomes in patients with CHD. Further, the associations of Aβ40 levels with arterial stiffness progression, incident subclinical atherosclerosis and incident CHD were addressed. Results: In Cox proportional-hazards models adjusted for age, gender, glomerular filtration rate, left ventricular ejection fraction, high-sensitivity C-reactive protein and high-sensitivity troponin-T, Aβ40 was an independent predictor of CV death and MACE in patients with CHD (P<0.05 for all). After multivariate adjustment, Aβ40 levels conferred a substantial enhancement of net reclassification index (continuous NRI value and 95% confidence interval: 36.7%, 12.5-60.7, P=0.001) and integrated discrimination improvement (IDI value±SE: 1.92±0.62, P<0.001) of individuals at risk in the total combined CHD cohort over the best predictive model. Further cohort-based analysis revealed that Aβ40 levels were significantly and independently associated with arterial stiffness progression, incident subclinical atherosclerosis and incident CHD. Conclusions: Measuring blood levels of Aβ40 identifies patients at high risk for cardiovascular death.

Prediction of Cancer and Coronary Heart Disease as a Function of Method of Questionnaire Administration1

1993 ◽  
Vol 73 (3_part_1) ◽  
pp. 943-959 ◽  
Author(s):  
R. Grossarth-Maticek ◽  
H. J. Eysenck ◽  
P. Barrett
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Personality Traits ◽  
Healthy Subjects ◽  
Intermediate Results ◽  
Different Levels ◽  
Personality And Stress

We have tested the hypothesis in this study that different methods of administering a questionnaire produce differential approximations to truthful admission of undesirable personality traits and behaviours. Four different methods of administration produced different levels of trust and understanding, using the current prediction among healthy subjects of death by cancer or coronary heart disease 13 years later as the criterion. There were significant differences in the accuracy of the predictions, depending crucially on the method of administration of the questionnaires. Best predictions were achieved for subjects when both trust and understanding had been increased by interviewers’ suitable participation; worst results were achieved for subjects when no special effort was made to increase either. Intermediate results were found for procedures which increased either trust or understanding. It is argued that the success or failure of studies investigating the influence of personality and stress on diseases like cancer and coronary heart disease may depend crucially on the adopted method of interrogation.

scholarly journals The Serum Analysis of Dampness Syndrome in Patients with Coronary Heart Disease and Chronic Renal Failure Based on the Theory of “Same Syndromes in Different Diseases”

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Yiming Hao ◽  
Xue Yuan ◽  
Peng Qian ◽  
Guanfeng Bai ◽  
Yiqin Wang
Keyword(s):  
Coronary Heart Disease ◽  
Renal Failure ◽  
Heart Disease ◽  
Chronic Renal Failure ◽  
Healthy Subjects ◽  
Principal Component ◽  
Serum Samples ◽  
Serum Metabolites ◽  
Underlying Basis ◽  
Patient Groups

Aim. To analyze the serum metabolites in patients with coronary heart disease (CHD) showing dampness syndrome and patients with chronic renal failure (CRF) showing dampness syndrome and to seek the substance that serves as the underlying basis of dampness syndrome in “same syndromes in different diseases.” Methods. Metabolic spectrum by GC-MS was performed using serum samples from 29 patients with CHD showing dampness syndrome and 32 patients with CRF showing dampness syndrome. The principal component analysis and statistical analysis of partial least squares were performed to detect the metabolites with different levels of expression in patients with CHD and CRF. Furthermore, by comparing the VIP value and data mining in METLIN and HMDB, we identified the common metabolites in both patient groups. Results. (1) Ten differential metabolites were found in patients with CHD showing dampness syndrome when compared to healthy subjects. Meanwhile, nine differential metabolites were found in patients with CRF showing dampness syndrome when compared to healthy subjects. (2) There were 9 differential metabolites identified when the serum metabolites of the CHD patients with dampness syndrome were compared to those of CRF patients with dampness syndrome. There were 4 common metabolites found in the serums of both patient groups.

Influence of external periodic stimuli on heart rate variability in healthy subjects and in coronary heart disease patients

2006 ◽  
Vol 32 (5) ◽  
pp. 565-573 ◽  
Author(s):  
V. I. Gridnev ◽  
A. R. Kiselev ◽  
E. V. Kotel’nikova ◽  
O. M. Posnenkova ◽  
P. Ya. Dovgalevskii ◽  
...  
Keyword(s):  
Heart Rate ◽  
Coronary Heart Disease ◽  
Heart Rate Variability ◽  
Heart Disease ◽  
Healthy Subjects

991 COMPARISON OF RISK FOR CORONARY HEART DISEASE IN PATIENTS WITH NAFLD, CHRONIC HEPATITIS C AND HEALTHY SUBJECTS

2009 ◽  
Vol 50 ◽  
pp. S359 ◽  
Author(s):  
S. Dragneva ◽  
D. Valcheva ◽  
A. Markova ◽  
R. Ivanova ◽  
D. Stanchev ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Chronic Hepatitis ◽  
Heart Disease ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Healthy Subjects

scholarly journals Increased Serum Cholesterol Esterification Rates Predict Coronary Heart Disease and Sudden Death in a General Population

2013 ◽  
Vol 33 (5) ◽  
pp. 1098-1104 ◽  
Author(s):  
Shin-ichiro Tanaka ◽  
Tomoyuki Yasuda ◽  
Tatsuro Ishida ◽  
Yoshio Fujioka ◽  
Takeshi Tsujino ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
General Population ◽  
Sudden Death ◽  
Serum Cholesterol ◽  
Cholesterol Esterification
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