Use of the Tumor Repressor DEDD as a Prognostic Marker of Cancer Metastasis

2014 ◽  
pp. 197-222 ◽  
Author(s):  
Qi Lv ◽  
Fang Hua ◽  
Zhuo-Wei Hu
Keyword(s):  
Prognostic Marker ◽  
Cancer Metastasis

scholarly journals Complete loss of PTEN expression as a possible early prognostic marker for prostate cancer metastasis

2007 ◽  
Vol 120 (6) ◽  
pp. 1284-1292 ◽  
Author(s):  
Martine Schmitz ◽  
Gérard Grignard ◽  
Christiane Margue ◽  
Walter Dippel ◽  
Catherine Capesius ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Prognostic Marker ◽  
Cancer Metastasis ◽  
Complete Loss ◽  
Pten Expression ◽  
Prostate Cancer Metastasis

scholarly journals LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker

2012 ◽  
Vol 18 (10) ◽  
pp. 1511-1517 ◽  
Author(s):  
Dahu Chen ◽  
Yutong Sun ◽  
Yongkun Wei ◽  
Peijing Zhang ◽  
Abdol Hossein Rezaeian ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Marker ◽  
Cancer Metastasis ◽  
Breast Cancer Metastasis ◽  
Metastasis Suppressor ◽  
Breast Cancer Metastasis Suppressor

Cathepsin D Concentration in Breast Cancer Cytosols: Correlation with Disease-Free Interval and Overall Survival

1992 ◽  
Vol 38 (10) ◽  
pp. 2114-2116 ◽  
Author(s):  
M J Duffy ◽  
D Reilly ◽  
J P Brouillet ◽  
E W McDermott ◽  
C Faul ◽  
...  
Keyword(s):  
Overall Survival ◽  
Prognostic Marker ◽  
Cathepsin D ◽  
Cancer Metastasis ◽  
Chi Square ◽  
Disease Free Interval ◽  
Free Interval ◽  
Low Concentrations ◽  
High Concentrations ◽  
Disease Free

Abstract Cathepsin D (CD) is an aspartyl protease implicated in cancer metastasis. In this study of 331 patients, we show that patients with primary breast carcinomas containing high concentrations of CD have a significantly shorter disease-free interval (chi-square = 4.28, P < 0.05) and overall survival (chi-square = 7.7, P < 0.01) than patients with low concentrations. CD as a prognostic marker for overall survival was equally valuable for women younger (chi-square = 4.39, P < 0.05) and older (chi-square = 3.97, P < 0.05) than 50 years. CD was also a significant prognostic marker for overall survival within the estradiol receptor (ER)-positive subgroup of patients (chi-square = 5.79, P < 0.025), but not in the ER-negative subgroup. Patients with tumors containing high concentrations of CD and low concentrations of ER had shorter disease-free intervals (chi-square = 15.1, P < 0.001) and lower overall survival (chi-square = 20.9, P < 0.001) than patients with high concentrations of ER but low concentrations of CD.

scholarly journals Comprehensive Analysis of Aberrantly Expressed Profiles of ncRNAs Revealed lncRNA AGPAT4-IT1 is a Potential Prognostic Marker for Breast Cancer Metastasis

2020 ◽  
Author(s):  
Feng chun Zhang ◽  
ning ning yan ◽  
Ming jun Li ◽  
Ying chun Xu ◽  
Xing ya Li
Keyword(s):  
Breast Cancer ◽  
Prognostic Marker ◽  
Cancer Metastasis ◽  
Breast Cancer Metastasis ◽  
Bioinformatics Analyses ◽  
Functional Roles ◽  
Kaplan Meier ◽  
Non Coding Rnas ◽  
Microarray Analyses ◽  
The Relationship

Abstract Aims: we investigated the relationship between long non-coding RNAs (lncRNAs) and breast cancer lung metastasis (BCLM). Methods: We performed lncRNA microarray analyses to establish the lncRNA profile of BCLM. Bioinformatics analyses were carried out to analyzed functional roles of identified lncRNAs. Kaplan-meier analysis was conducted to determine the relation between lncRNA AGPAT4-IT1 and prognosis of breast cancer. Results: We found 317 upregulated and 166 downregulated lncRNAs in BCLM group. We showed AGPAT4-IT1 was positively correlated with its parental gene APGAT4. Furthermore, we suggested AGPAT4-IT1 were highly expressed in higher tumour grade and predicted poorer prognosis. Conclusions: These findings provide evidence for exploring the mechanisms of BCLM and indicate AGPAT4-IT1 is a prospective prognostic marker for breast cancer metastasis.

386: Nuclear Localization of ERBB3: A Potential Diagnostic/Prognostic Marker of Prostate Cancer

2005 ◽  
Vol 173 (4S) ◽  
pp. 105-106
Author(s):  
Ismaël H. Koumakpayi ◽  
Jean-Simon Diallo ◽  
Cecile Le Page ◽  
Laurent Lessard ◽  
Martin E. Gleave ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Prognostic Marker ◽  
Nuclear Localization

1068: TP53 Gene Mutations as a Prognostic Marker for PSA Progression in Early Stage Prostate Cancer

2004 ◽  
Vol 171 (4S) ◽  
pp. 282-282
Author(s):  
Markus D. Sachs ◽  
Horst Schlechte ◽  
Katrin Schiemenz ◽  
Severin V. Lenk ◽  
Dietmar Schnorr ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Prognostic Marker ◽  
Early Stage ◽  
Gene Mutations ◽  
Tp53 Gene ◽  
Psa Progression ◽  
Tp53 Gene Mutations

622 Blood urea nitrogen — an important prognostic marker in patients with chronic heart failure

2006 ◽  
Vol 5 (1) ◽  
pp. 145-146
Author(s):  
M ROIK ◽  
M STARCZEWSKA ◽  
S STAWICKI ◽  
Z HUCZEK ◽  
J KOCHANOWSKI ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Prognostic Marker ◽  
Blood Urea Nitrogen ◽  
Urea Nitrogen
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