Characterization of Formulations for Freeze-Drying

2018 ◽  
pp. 1-32
Author(s):  
Kevin R. Ward ◽  
Paul Matejtschuk
Keyword(s):  
Freeze Drying

Preparation and Characterization of Chitosan-Based Scaffolds for Biomedical Applications

2006 ◽  
Vol 514-516 ◽  
pp. 1005-1009 ◽  
Author(s):  
José V. Araújo ◽  
J.A. Lopes da Silva ◽  
Margarida M. Almeida ◽  
Maria Elisabete V. Costa
Keyword(s):  
Biomedical Applications ◽  
Freeze Drying ◽  
Average Pore Size ◽  
Composite Scaffolds ◽  
Average Pore ◽  
Chitosan Matrix ◽  
Freeze Dried ◽  
Porous Chitosan ◽  
Interconnected Structure

Porous chitosan/brushite composite scaffolds were prepared by a freeze-drying technique, starting from brushite suspensions in chitosan solutions. The obtained scaffolds showed a regular macroporous and interconnected structure with brushite particles uniformly distributed in the chitosan matrix. The variation of the brushite concentration affected the microstructure of the final freeze-dried scaffold, in particular, its porosity and its average pore size. The yield strengths of the composite scaffolds could also be improved by the increase of the brushite content.

scholarly journals Characterization of Inclusion Complex of Croton zehntneri Essential Oil and β-Cyclodextrin Prepared by Spray Drying and Freeze Drying

2019 ◽  
Vol 11 (2) ◽  
pp. 529-542 ◽  
Author(s):  
Lorenna Fonseca ◽  
Marcio dos S. Rocha ◽  
Larisse C. F. Brito ◽  
Edymilaís S. Sousa ◽  
Fernanda S. Reinaldo ◽  
...  
Keyword(s):  
Essential Oil ◽  
Inclusion Complex ◽  
Spray Drying ◽  
Freeze Drying

scholarly journals Synthesis and Characterization of Nanosized of Spinel LiMn2O4via Sol-gel and Freeze Drying Methods

2013 ◽  
Vol 34 (2) ◽  
pp. 622-628 ◽  
Author(s):  
Masoud Seyedahmadian ◽  
Shadi Houshyarazar ◽  
Ahmad Amirshaghaghi
Keyword(s):  
Freeze Drying ◽  
Sol Gel ◽  
Synthesis And Characterization ◽  
Drying Methods

Preparation and characterization of nano amitriptyline hydrochloride particles by spray freeze drying

Nanomedicine ◽  
2019 ◽  
Vol 14 (12) ◽  
pp. 1521-1531
Author(s):  
Yingjie Hu ◽  
Chunyan Ma ◽  
Mengxia Sun ◽  
Changping Guo ◽  
Jinpeng Shen ◽  
...  
Keyword(s):  
Freeze Drying ◽  
Spray Freeze Drying ◽  
Amitriptyline Hydrochloride

XPS Studies of the Interactions of Biocells with Various Silicon Based Surfaces

1995 ◽  
Vol 414 ◽  
Author(s):  
S. Seal ◽  
S. Krezoski ◽  
T. L. Barr ◽  
D. H. Petering
Keyword(s):  
Surface Chemistry ◽  
Tumor Cells ◽  
Photoelectron Spectroscopy ◽  
Freeze Drying ◽  
Chemical Characterization ◽  
Chrysotile Asbestos ◽  
X Ray ◽  
Silicon Based ◽  
Rat Tumor

AbstractSiliceous materials are the principal components of Earth's crust and also have become key ingredients of modem technology. Recently, we have expanded our chemical characterization of complex silicates (e.g., framework [1] and sheet types [2]) to include studies of their interaction with select biocells [3,4]. It is becoming apparent that the surface chemistry of these silicates, and perhaps that of silica itself, plays a key role in the oft resulting cell pathogenesis, thus enhancing the value of further investigations with X-ray photoelectron spectroscopy. The present research describes the unique growth of Ehrlich (murine or rat tumor) cells on Sio and SiO2 wafers, and also on select seaentine silicates (such as chrysotile asbestos). Tbese growth studies were followed by both cell/silicate separations and unique freeze drying [3,4]. XPS examination at select stages discovered cell induced alterations in the Si, O, Mg and particularly Fe chemistry of the silicon based systems as well as corresponding changes in the cell chemistry. Many of these features were confirmed by atomic absorption spectroscopy.

Preparation and Characterization of a Bio-Composites Scaffold Containing Nano-Hydroxyapatite /Carboxymethyl Chitosan

2012 ◽  
Vol 476-478 ◽  
pp. 2055-2058 ◽  
Author(s):  
Zhi Hua Lu ◽  
Dong Mei Zhao ◽  
Kang Ning Sun
Keyword(s):  
Mechanical Properties ◽  
Freeze Drying ◽  
Crystallization Process ◽  
Average Diameter ◽  
Carboxymethyl Chitosan ◽  
Hydroxyl Group ◽  
Sem Images ◽  
Homogenous Distribution ◽  
Potential Use

In this study, a genipin cross linked scaffold containing nano-hydroxyapatite (n-HAp) and carboxymehthyl chitosan (CMCS) was developed by freeze drying technique. The scaffolds were characterized using FTIR, XRD and SEM. The cytotoxicity of the scaffolds was compared with scaffolds cross linked by glutaraldehyde, and the Young’s modulus was also tested. FTIR and XRD results indicated that CMCS’s hydroxyl group, amino and amide regulated the n-HAp crystallization process, which results in the nano homogenous distribution of n-HAp and provided nano topographical features for nanohybrid scaffolds. SEM images revealed the scaffolds had porous structure and the pores were interconnected with an average diameter of 150 μm, which was profit for the growth of tissues. Cell morphology showed the genipin cross linked scaffolds had less toxicity and more facility for adhesion and proliferation of cells. Great mechanical properties of the scaffolds indicate their potential use in bone tissue engineering.

Sign in / Sign up

Export Citation Format

Share Document