Bioactive Compounds of Drumstick (Moringa oleifera Lam.)

2020 ◽  
pp. 1-17
Author(s):  
Balkrishna A. Shinde ◽  
Avinash C. Kamble
Keyword(s):  
Bioactive Compounds ◽  
Moringa Oleifera ◽  
Moringa Oleifera Lam

Bioaccessibility, antioxidant activity and modulation effect on gut microbiota of bioactive compounds from Moringa oleifera Lam. leaves during digestion and fermentation in vitro

2019 ◽  
Vol 10 (8) ◽  
pp. 5070-5079 ◽  
Author(s):  
Zuman Dou ◽  
Chun Chen ◽  
Xiong Fu
Keyword(s):  
Antioxidant Activity ◽  
Gut Microbiota ◽  
Bioactive Compounds ◽  
Moringa Oleifera ◽  
Modulation Effect ◽  
Gastrointestinal Digestion ◽  
Colonic Fermentation ◽  
Moringa Oleifera Lam

This study aims to investigate the bioaccessibility, bioactivity and gut microbiota modulation effect of Moringa oleifera Lam. leaves after in vitro gastrointestinal digestion and colonic fermentation.

Bioactive Compounds of Drumstick (Moringa oleifera Lam.)

2020 ◽  
pp. 573-589
Author(s):  
Balkrishna A. Shinde ◽  
Avinash C. Kamble
Keyword(s):  
Bioactive Compounds ◽  
Moringa Oleifera ◽  
Moringa Oleifera Lam

scholarly journals Identification of Bioactive Compounds in the Ethanolic and Hexanic Extracts of Moringa oleifera Lam. Leaves

2021 ◽  
Author(s):  
Maria de Sousa Santos Bezerra ◽  
Herbert Gonzaga de Sousa ◽  
Maria Jisele dos Passos Santos ◽  
Johnnatan Duarte de Freitas ◽  
Mirelle Márcio Santos Cabral ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Moringa Oleifera ◽  
Moringa Oleifera Lam

scholarly journals In Vitro Bioassay-Guided Identification of Anticancer Properties from Moringa oleifera Lam. Leaf against the MDA-MB-231 Cell Line

2020 ◽  
Vol 13 (12) ◽  
pp. 464
Author(s):  
Prapakorn Wisitpongpun ◽  
Nungruthai Suphrom ◽  
Pachuen Potup ◽  
Nitra Nuengchamnong ◽  
Philip C. Calder ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Moringa Oleifera ◽  
Anticancer Activities ◽  
Etoac Extract ◽  
Apoptosis Pathway ◽  
Anticancer Properties ◽  
Cycle Arrest ◽  
Bioassay Guided Fractionation ◽  
Moringa Oleifera Lam

Moringa oleifera Lam. (MO) is a medicinal plant distributed across the Middle East, Asia, and Africa. MO has been used in the traditional treatment of various diseases including cancer. This study aimed to perform bioassay-guided fractionation and identification of bioactive compounds from MO leaf against MDA-MB-231 breast cancer cells. MO leaf was sequentially extracted with hexane, ethyl acetate (EtOAc), and ethanol. The most effective extract was subjected to fractionation. MO extract and its derived fractions were continuously screened for anti-cancer activities. The strongest fraction was selected for re-fractionation and identification of bioactive compounds using LC-ESI-QTOF-MS/MS analysis. The best anticancer activities were related to the fraction no. 7-derived crude EtOAc extract. This fraction significantly reduced cell viability and clonogenic growth and increased cells apoptosis. Moreover, sub-fraction no. 7.7-derived fraction no. 7 was selected for the identification of bioactive compounds. There were 10 candidate compounds tentatively identified by LC-ESI-QTOF-MS. Three of identified compounds (7-octenoic acid, oleamide, and 1-phenyl-2-pentanol) showed anticancer activities by inducing cell cycle arrest and triggering apoptosis through suppressed Bcl-2 expression which subsequently promotes activation of caspase 3, indicators for the apoptosis pathway. This study identified 10 candidate compounds that may have potential in the field of anticancer substances.

scholarly journals Foliar Application of Cu Nanoparticles Modified the Content of Bioactive Compounds in Moringa oleifera Lam

Agronomy ◽  
2018 ◽  
Vol 8 (9) ◽  
pp. 167 ◽  
Author(s):  
Antonio Juárez-Maldonado ◽  
Hortensia Ortega-Ortíz ◽  
Gregorio Cadenas-Pliego ◽  
Jesús Valdés-Reyna ◽  
José Pinedo-Espinoza ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Bioactive Compounds ◽  
Nutritional Value ◽  
Moringa Oleifera ◽  
Foliar Application ◽  
Bioactive Compound ◽  
Cu Nanoparticles ◽  
Chlorophyll Contents ◽  
Moringa Oleifera Lam

Moringa oleifera Lam is a plant that has recently gained importance as a food because of its nutritional value and bioactive compound content and because practically all the organs are usable. The use of nanoparticles has appeared as an alternative to increase bioactive compounds in plants. The goal of this work was to determine if the application of copper nanoparticles would increase the content of bioactive compounds and antioxidant capacity in M. oleifera. Copper (Cu) nanoparticles were applied to the leaves at four different times throughout crop growth. The biocompounds were analyzed after the second, third, and fourth applications. The results show that application of Cu nanoparticles has a beneficial effect on the accumulation of bioactive compounds in M. oleifera leaves. In addition, the antioxidant capacity and carotenoid and chlorophyll contents in the leaves of M. oleifera increased after Cu nanoparticles application. The same effect was not observed in the fruit of M. oleifera. Here, the bioactive compound contents diminished. Therefore, the use of Cu nanoparticles can be an important alternative to improve the quality of this plant, particularly that of the leaves.

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