Purchase System for People with Reduced Mobility: Promoting Equity Idealized by Society 5.0

2020 ◽  
pp. 451-462
Author(s):  
Ana Paula Braga Garcez ◽  
Ricardo Moreira da Silva ◽  
Luís Carlos Inácio de Matos ◽  
Tânia Daniela Felgueiras Miranda Lima ◽  
César Emanoel Barbosa de Lima ◽  
...  
Keyword(s):  
Reduced Mobility

Motility of leukemic lymphocytes

1990 ◽  
Vol 48 (3) ◽  
pp. 368-369
Author(s):  
Manoj Raje ◽  
Karvita B. Ahluwalia
Keyword(s):  
Quantitative Data ◽  
Laser Doppler Velocimetry ◽  
Acute Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Cellular Space ◽  
Differentiated Cells ◽  
Poorly Differentiated ◽  
Solid Tissues ◽  
Well Differentiated ◽  
Reduced Mobility

In Acute Lymphocytic Leukemia motility of lymphocytes is associated with dissemination of malignancy and establishment of metastatic foci. Normal and leukemic lymphocytes in circulation reach solid tissues where due to in adequate perfusion some cells get trapped among tissue spaces. Although normal lymphocytes reenter into circulation leukemic lymphocytes are thought to remain entrapped owing to reduced mobility and form secondary metastasis. Cell surface, transmembrane interactions, cytoskeleton and level of cell differentiation are implicated in lymphocyte mobility. An attempt has been made to correlate ultrastructural information with quantitative data obtained by Laser Doppler Velocimetry (LDV). TEM of normal & leukemic lymphocytes revealed heterogeneity in cell populations ranging from well differentiated (Fig. 1) to poorly differentiated cells (Fig. 2). Unlike other cells, surface extensions in differentiated lymphocytes appear to originate by extrusion of large vesicles in to extra cellular space (Fig. 3). This results in persistent unevenness on lymphocyte surface which occurs due to a phenomenon different from that producing surface extensions in other cells.

scholarly journals Ground-Based MAX-DOAS Observations of Tropospheric NO2 and HCHO During COVID-19 Lockdown and Spring Festival Over Shanghai, China

2021 ◽  
Vol 13 (3) ◽  
pp. 488
Author(s):  
Aimon Tanvir ◽  
Zeeshan Javed ◽  
Zhu Jian ◽  
Sanbao Zhang ◽  
Muhammad Bilal ◽  
...  
Keyword(s):  
Air Quality ◽  
Anthropogenic Activities ◽  
Anthropogenic Activity ◽  
Hysplit Model ◽  
Vertical Column ◽  
Weekly Cycle ◽  
Spring Festival ◽  
Level 1 ◽  
Reduced Mobility ◽  
The Impact

Reduced mobility and less anthropogenic activity under special case circumstances over various parts of the world have pronounced effects on air quality. The objective of this study is to investigate the impact of reduced anthropogenic activity on air quality in the mega city of Shanghai, China. Observations from the highly sophisticated multi-axis differential optical absorption spectroscope (MAX-DOAS) instrument were used for nitrogen dioxide (NO2) and formaldehyde (HCHO) column densities. In situ measurements for NO2, ozone (O3), particulate matter (PM2.5) and the air quality index (AQI) were also used. The concentration of trace gases in the atmosphere reduces significantly during annual Spring Festival holidays, whereby mobility is reduced and anthropogenic activities come to a halt. The COVID-19 lockdown during 2020 resulted in a considerable drop in vertical column densities (VCDs) of HCHO and NO2 during lockdown Level-1, which refers to strict lockdown, i.e., strict measures taken to reduce mobility (43% for NO2; 24% for HCHO), and lockdown Level-2, which refers to relaxed lockdown, i.e., when the mobility restrictions were relaxed somehow (20% for NO2; 22% for HCHO), compared with pre-lockdown days, as measured by the MAX-DOAS instrument. However, for 2019, a reduction in VCDs was found only during Level-1 (24% for NO2; 6.62% for HCHO), when the Spring Festival happened. The weekly cycle for NO2 and HCHO depicts no significant effect of weekends on the lockdown. After the start of the Spring Festival, the VCDs of NO2 and HCHO showed a decline for 2019 as well as 2020. Backward trajectories calculated using the Hybrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) model indicated more air masses coming from the sea after the Spring Festival for 2019 and 2020, implying that a low pollutant load was carried by them. No impact of anthropogenic activity was found on O3 concentration. The results indicate that the ratio of HCHO to NO2 (RFN) fell in the volatile organic compound (VOC)-limited regime.

scholarly journals Agricultural Cooperatives and COVID-19 in Southeast Africa. The Role of Managerial Capital for Rural Resilience

2021 ◽  
Vol 13 (3) ◽  
pp. 1046
Author(s):  
Nicola Francesconi ◽  
Fleur Wouterse ◽  
Dorothy Birungi Namuyiga
Keyword(s):  
Health Impact ◽  
Value Chains ◽  
Agricultural Cooperatives ◽  
African Countries ◽  
Elite Capture ◽  
Innovative Solutions ◽  
Reduced Mobility ◽  
The Impact ◽  
Food Value

While the health impact of COVID-19 in most African countries appears modest, the impact of social distancing measures, closing of markets and reduced mobility is felt across the board. Domestic, labor-intensive and traditional food value chains and the smallholders they serve appear to be particularly affected. During a systemic shock where idiosyncratic risk coping strategies fail, collective or organizational resilience becomes of the essence to protect the livelihoods of smallholders. In this study, we have used pre- and during-shock data on agricultural cooperatives from Southeast Africa to understand how resilient these smallholder-owned organizations are. We find that many organizations could not countervail market-disruptions and fell into a state of dormancy during the pandemic. One reason for this is that collective decision-making was heavily affected by the banning of gatherings. Only a few organizations devised innovative solutions to maintain the market linkages of rural smallholders. The lack of resilience demonstrated by most cooperatives appears to be associated with organizational immaturity, large membership size, elite capture and limited business-orientation, which underscore a general lack of managerial capital.

scholarly journals On the Mechanism of H2 Formation in the Interstellar Medium

1987 ◽  
Vol 120 ◽  
pp. 167-169
Author(s):  
Valerio Pirronello
Keyword(s):  
Interstellar Medium ◽  
Molecular Hydrogen ◽  
Formation Rate ◽  
Cosmic Ray ◽  
Interstellar Clouds ◽  
H2 Formation ◽  
Reduced Mobility

The problem of the formation of molecular hydrogen in interstellar clouds is revisited. the role played by cosmic ray bombardment under certain circumstances is considered mainly in the light of the low formation rate of H2 on grains due to the reduced mobility of adsorbed H atoms on their amorphous surfaces at interstellar temperatures.

scholarly journals Reduced Germline Mobility of a mariner Vector Containing Exogenous DNA: Effect of Size or Site?

Genetics ◽  
1996 ◽  
Vol 143 (3) ◽  
pp. 1299-1306 ◽  
Author(s):  
Allan R Lohe ◽  
Daniel L Hartl
Keyword(s):  
Genetic Engineering ◽  
Transposable Element ◽  
Frequency Analysis ◽  
Relative Stability ◽  
Low Frequency ◽  
Economic Importance ◽  
Exogenous Dna ◽  
Valuable Property ◽  
Reduced Mobility

Abstract Germline mobilization of the transposable element mariner is severely inhibited by the insertion of a 4.5- to 11.9-kb fragment of exogenous DNA into a unique SacI site approximately in the middle of the 1286bp element. In the presence of transposase driven by the germline-specific hsp26-sgs3 promoter, mobilization of the MlwB construct (containing a 11.9-kb insertion) is detected at low frequency. Analysis of a mobilized MlwB element indicated that mobilization is mediated by the marinertransposase. However, transposed MlwB elements are also defective in germline mobilization. Rare, transposase-induced germline excision events were also recovered for such vectors. The estimated rate of excision is <0.1% per chromosome per generation. Excision appears to be accompanied by gap repair if a suitable template is available. The data imply that the reduced mobility of mariner vectors with exogenous DNA in the SacI site results from disruption of sequences necessary for efficient mobilization. The relative stability may be a valuable property in the uses of mariner-like elements in genetic engineering of insects of economic importance.

scholarly journals Human Nonmercaptalbumin Is a New Biomarker of Motor Function

2021 ◽  
Vol 10 (11) ◽  
pp. 2464
Author(s):  
Sadayuki Ito ◽  
Hiroaki Nakashima ◽  
Kei Ando ◽  
Kazuyoshi Kobayashi ◽  
Masaaki Machino ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Grip Strength ◽  
Motor Function ◽  
Walking Speed ◽  
The Elderly ◽  
Elderly Subjects ◽  
Locomotive Syndrome ◽  
Reduced Mobility

The ratio of human nonmercaptalbumin (HNA) and reduced albumin (HMA) may be a new marker for oxidative stress. Locomotive syndrome (LS) is reduced mobility due to impairment of locomotive organs. We investigated whether the HNA/HMA ratio could be a new biomarker of LS. This study included 306 subjects (mean age 64.24 ± 10.4 years) who underwent LS tests, grip strength, walking speed, and tests for HNA and HMA. Oxidative stress was measured by the ratio of HMA (f(HMA) = (HMA/(HMA + HNA) × 100)), and the subjects were divided into normal (N group; f[HMA] ≥ 70%) and low (L group; f[HMA] < 70%) groups. There were 124 non-elderly (<65 years) and 182 elderly subjects (≥65 years). There were no significant differences in LS, grip strength, and walking speed between the L and N groups in the non-elderly subjects. However, significant differences were found in the elderly subjects. In logistic regression analysis, there was an association between f(HMA) and the LS severity at older ages. LS in the elderly is associated with a decline in HMA and, thus, an increase in oxidative stress. Thus, f(HMA) is a new biomarker of LS.

CASE STUDY: MANAGEMENT OF PATIENT WITH SHOULDER PAIN BY GENERAL PRACTITIONER

2021 ◽  
Author(s):  
V. M. Nazarian ◽  
V. I. Velichko ◽  
V. I. Synenko ◽  
S. F. Kovalenko
Keyword(s):  
General Practitioner ◽  
Rotator Cuff ◽  
Shoulder Pain ◽  
Pathological Process ◽  
Autologous Plasma ◽  
Appropriate Treatment ◽  
Inflammatory Drugs ◽  
Pharmacological Method ◽  
Reduced Mobility

Shoulder pain is one of the most common presentations of musculoskeletal pain with population prevalence of between 7 and 26 %. The most common pathology that affects the shoulder joint is rotator cuff syndrome. The most important aspects in the management of patient with shoulder pain by general practitioner are to ensure an accurate diagnosis and to start the appropriate treatment on time. The main direction of rotator cuff syndrome treatment includes a period of rest from the exacerbating activity and taking nonsteroidal anti-inflammatory drugs. In some cases the use of the NSAIDs is not possible, so we decided to suggest an alternative non-pharmacological method of treatment. We treated a patient with rotator cuff syndrome by injections of autologous plasma into the affected muscles and projections of entheses that were involved in the pathological process. We obtained positive results. The shoulder pain had been reduced, mobility and movement had been improved after a course of autologous plasma injections. In our opinion, it is expedient to consider such treatment of the rotator cuff syndrome both as an additional method and separately in case of impossibility of prescribing the main therapy.

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