The digital transformation represents across the globe a new stage in the profound economic and social reorganization, that has been engaged for several decades under the effect of information technology [1]. Digital transformation (DT) is the use of digital advances to change customer relationships, internal processes, and value propositions [2]. The biggest future impact on revenue and EBIT growth can be generated through the digitization of supply chains [3]. In this context, the present paper proposes to apply digital transformation to supply chain, and especially to “order to cash” cycle, through an experimentation of the “Supply Chain Urbanization” model (SCU) [4, 5]. We will start in this paper by presenting the “order to cash” cycle according to various references; we will next emphasize Digital transformation before highlighting the “Digital transformation in “order to cash” cycle. We will after illuminate the different phases of the “Supply Chain Urbanization” model (SCU) [4, 5], and then experiment this model on supply chain digital transformation. The "Order to Cash" cycle will be the main link in the supply chain studied in our article.