Cardiovascular Diseases in Pregnancy

Author(s):  
Obasohan Austine ◽  
Aiwuyo O. Henry
ESC CardioMed ◽  
2018 ◽  
pp. 2876-2882
Author(s):  
Stefan Verlohren

Pregnant women with pre-existing cardiovascular disease may require drug therapy during their pregnancy and lactation period. There are no uniform recommendations for selection of medications, dosing, and timing of treatment. Possible adverse or teratogenic effects of the drugs on the fetus must be weighed against the maternal indication of drug treatment. This chapter gives an overview of medical treatment options for cardiovascular diseases in pregnancy. Furthermore, sources of evidence which can be used for risk classification of drugs applied during pregnancy are shown.


2021 ◽  
Vol 135 (12) ◽  
pp. 1523-1544
Author(s):  
Jessica L. Faulkner

Abstract The pathogenesis of obesity-associated cardiovascular diseases begins long prior to the presentation of a cardiovascular event. In both men and women, cardiovascular events, and their associated hospitalizations and mortality, are often clinically predisposed by the presentation of a chronic cardiovascular risk factor. Obesity increases the risk of cardiovascular diseases in both sexes, however, the clinical prevalence of obesity, as well as its contribution to crucial cardiovascular risk factors is dependent on sex. The mechanisms via which obesity leads to cardiovascular risk is also discrepant in women between their premenopausal, pregnancy and postmenopausal phases of life. Emerging data indicate that at all reproductive statuses and ages, the presentation of a cardiovascular event in obese women is strongly associated with hypertension and its subsequent chronic risk factor, heart failure with preserved ejection fraction (HFpEF). In addition, emerging evidence indicates that obesity increases the risk of both hypertension and heart failure in pregnancy. This review will summarize clinical and experimental data on the female-specific prevalence and mechanisms of hypertension and heart failure in women across reproductive stages and highlight the particular risks in pregnancy as well as emerging data in a high-risk ethnicity in women of African ancestry (AA).


Author(s):  
E. Baranova ◽  
O. Bolshakova

Arterial hypertension in pregnancy is now believed to be a risk factor for future maternal cardiovascular diseases. Despite the low immediate cardiovascular risk in a population of young women, a pregnancy complicated with hypertension carries a significant additional risk of future disease.


Author(s):  
А.А. Аракелянц ◽  
Т.Е. Морозова ◽  
Е.А. Барабанова ◽  
Е.О. Самохина

У здоровой женщины при нормально протекающей беременности структурно-функциональные изменения сердца носят адаптивный характер, выражены незначительно и полностью нормализуются после родов. У беременной с теми или иными заболеваниями сердца адаптационные возможности снижены, поэтому на любом этапе беременности могут возникать патологические изменения, осложняющие ее течение и приводящие к неблагоприятным исходам. Кроме того, при любой беременности возможно развитие новых заболеваний сердца, которые могут быть фатальными. Вот почему эхокардиографическая оценка структурно-функциональных изменений сердца является необходимой как при нормальной беременности, так и на фоне сопутствующих сердечно-сосудистых заболеваний. In a healthy woman with a normal pregnancy, structural and functional changes in the heart are adaptive in nature, are slight and are completely normalized after childbirth. A pregnant woman with heart diseases has reduced adaptive capacity, therefore, at any stage of pregnancy, pathological changes can occur that complicate its course and lead to adverse outcomes. In addition, any pregnancy may develop new heart diseases, which can be fatal. That is why an echocardiographic assessment of structural and functional changes in the heart is necessary both during normal pregnancy and in the background of concomitant cardiovascular diseases.


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