scholarly journals Parameter Setting for Multicore CMA-ES with Large Populations

2016 ◽  
pp. 109-122 ◽  
Author(s):  
Nacim Belkhir ◽  
Johann Dréo ◽  
Pierre Savéant ◽  
Marc Schoenauer
Keyword(s):  
Parameter Setting ◽  
Large Populations

Morphogenetic machines revealed: Microscopy of living cells in the embryo of the frog, Xenopus laevis

1993 ◽  
Vol 51 ◽  
pp. 172-173
Author(s):  
Ray Keller
Keyword(s):  
Image Processing ◽  
Fluorescent Dyes ◽  
Cell Movement ◽  
Living Cells ◽  
Ease Of Use ◽  
Low Light ◽  
Amphibian Embryo ◽  
Large Populations ◽  
Light Fluorescence ◽  
Video Image Processing

The amphibian embryo offers advantages of size, availability, and ease of use with both microsurgical and molecular methods in the analysis of fundamental developmental and cell biological problems. However, conventional wisdom holds that the opacity of this embryo limits the use of methods in optical microscopy to resolve the cell motility underlying the major shape-generating processes in early development.These difficulties have been circumvented by refining and adapting several methods. First, methods of explanting and culturing tissues were developed that expose the deep, nonepithelial cells, as well as the superficial epithelial cells, to the view of the microscope. Second, low angle epi-illumination with video image processing and recording was used to follow patterns of cell movement in large populations of cells. Lastly, cells were labeled with vital, fluorescent dyes, and their behavior recorded, using low-light, fluorescence microscopy and image processing. Using these methods, the details of the cellular protrusive activity that drives the powerful convergence (narrowing)

The Use of Medical Record Linkage for Population and Genetic Studies

1969 ◽  
Vol 08 (01) ◽  
pp. 07-11 ◽  
Author(s):  
H. B. Newcombe
Keyword(s):  
Record Linkage ◽  
Large Scale ◽  
Medical Record Linkage ◽  
Canadian Province ◽  
Genetic Studies ◽  
Parental Characteristics ◽  
Family Histories ◽  
The Family ◽  
Large Populations ◽  
Machine Readable

Methods are described for deriving personal and family histories of birth, marriage, procreation, ill health and death, for large populations, from existing civil registrations of vital events and the routine records of ill health. Computers have been used to group together and »link« the separately derived records pertaining to successive events in the lives of the same individuals and families, rapidly and on a large scale. Most of the records employed are already available as machine readable punchcards and magnetic tapes, for statistical and administrative purposes, and only minor modifications have been made to the manner in which these are produced.As applied to the population of the Canadian province of British Columbia (currently about 2 million people) these methods have already yielded substantial information on the risks of disease: a) in the population, b) in relation to various parental characteristics, and c) as correlated with previous occurrences in the family histories.

An Enzyme Immunoassay (ELISA) for the Quantitation of Human Factor VII

1986 ◽  
Vol 56 (03) ◽  
pp. 250-255 ◽  
Author(s):  
C Boyer ◽  
M Wolf ◽  
C Rothschild ◽  
M Migaud ◽  
J Amiral ◽  
...  
Keyword(s):  
Human Factor ◽  
Solid Phase ◽  
Factor Vii ◽  
Enzyme Linked Immunosorbent Assay ◽  
Poor Correlation ◽  
Vein Thrombosis ◽  
Coagulant Activity ◽  
Significant Difference ◽  
Large Populations ◽  
Deep Vein

SummaryA new solid phase enzyme-linked immunosorbent assay (ELISA) was developed for the quantitation of human Factor VII antigen (F VII Ag), using a monospecific rabbit anti-F VII antiserum. Anti-F VII F(ab′)2 fragments were adsorbed to polystyrene plates. The binding of serial dilutions of control or test plasma, containing F VII, was detected by incubation with peroxidase-labeled anti- FV II IgG followed by the addition of hydrogen peroxyde and O-phenylenediamine. This ELISA is specific, sensitive (detection limit: 0.05%) and accurate (coefficient of variation: 1.5-4% for within- and 1.6-9% for between-assays). F VII coagulant activity (F VII C) and F VII Ag were determined in large populations of controls and patients. In normal plasma (n = 38), F VII Ag ranged from 83 to 117% and the correlation coefficient between F VII Ag and F VII C was 0.94. In patients with severe (F VII C inf. 1%) congenital F VII deficiency (n = 5), F VII Ag was undetectable in two cases (inf. 0.05%) and markedly reduced (0.35 to 5.6%) in the three other cases. In patients with liver cirrhosis (n = 15), F VII Ag ranged from 21 to 59% and was in good correlation with F VII C (r = 0.84). In dicoumarol treated patients (n = 15), the levels of F VII Ag ranged from 51% to 79% and a poor correlation (r = 0.52) with F VIIC was observed. In “compensated” DIC (n = 5), levels of F VII Ag varied from 60 to 186%, with significantly higher F VII C levels (from 143 to 189%). In contrast, in “decompensated” DIC (n = 7), low F VII Ag and F VII C levels were observed (from 7 to 27%). In patients with deep-vein thrombosis (n = 25), high levels of F VII Ag (from 102 to 136%) and F VII C (from 110 to 150%) were demonstrated. In surgical patients, no significant difference was observed before and one day after intervention.

Parameter Setting Procedure by using Golden Angle for Generation of Diversity

2014 ◽  
Vol 1 ◽  
pp. 146-149
Author(s):  
Takuya Shindo ◽  
Kenya jin'no
Keyword(s):  
Parameter Setting ◽  
Golden Angle

Galectin-3 in Heart Failure – Linking Fibrosis, Remodelling and Progression

2010 ◽  
Vol 6 (2) ◽  
pp. 33 ◽  
Author(s):  
Christopher R deFilippi ◽  
G Michael Felker ◽  
◽  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Risk Stratification ◽  
Cardiac Fibrosis ◽  
The Elderly ◽  
Preserved Ejection Fraction ◽  
Heart Failure Patients ◽  
Large Populations ◽  
Galectin 3

For many with heart failure, including the elderly and those with a preserved ejection fraction, both risk stratification and treatment are challenging. For these large populations and others there is increasing recognition of the role of cardiac fibrosis in the pathophysiology of heart failure. Galectin-3 is a novel biomarker of fibrosis and cardiac remodelling that represents an intriguing link between inflammation and fibrosis. In this article we review the biology of galectin-3, recent clinical research and its application in the management of heart failure patients.

Consular Protection and Solidarity across Borders

2018 ◽  
Author(s):  
Alexandra Délano Alonso
Keyword(s):  
United States ◽  
Latin American ◽  
Legal Status ◽  
Well Being ◽  
The United States ◽  
Migrant Populations ◽  
Policy Goals ◽  
Large Populations ◽  
Mexican Government ◽  
Working Together

This chapter demonstrates how Latin American governments with large populations of migrants with precarious legal status in the United States are working together to promote policies focusing on their well-being and integration. It identifies the context in which these processes of policy diffusion and collaboration have taken place as well as their limitations. Notwithstanding the differences in capacities and motivations based on the domestic political and economic contexts, there is a convergence of practices and policies of diaspora engagement among Latin American countries driven by the common challenges faced by their migrant populations in the United States and by the Latino population more generally. These policies, framed as an issue of rights protection and the promotion of migrants’ well-being, are presented as a form of regional solidarity and unity, and are also mobilized by the Mexican government as a political instrument serving its foreign policy goals.

Accessible Elections

2020 ◽  
Author(s):  
Michael Ritter ◽  
Caroline J. Tolbert
Keyword(s):  
Voter Turnout ◽  
Population Data ◽  
State Governments ◽  
Public Officials ◽  
Early Voting ◽  
Beneficial Effects ◽  
Election Reform ◽  
Individual Vote ◽  
Large Populations ◽  
Voting Methods

This book explores the wide variation across states in convenience voting methods—absentee/mail voting, in-person early voting, same day registration—and provides new empirical analysis of the beneficial effects of these policies, not only in increasing voter turnout overall, but for disadvantaged groups. By measuring both convenience methods and implementation of the laws, the book improves on previous research. It draws generalizable conclusions about how these laws affect voter turnout by using population data from the fifty state voter files. Using individual vote histories, the design helps avoid bias in non-random assignment of states in adopting the laws. Many scholars and public officials have dismissed state election reform laws as failing to significantly increase turnout or address inequality in who votes. Accessible Elections underscores how state governments can modernize their election procedures to increase voter turnout and influence campaign and party mobilization strategies. Mail voting and in-person early voting are particularly important in the wake of Covid-19 to avoid election day crowds and ensure successful and equitable elections in states with large populations; the results of this study can help state governments more rapidly update voting for the 2020 general election and beyond.

Outbreeding depression is uncommon and predictable

2017 ◽  
Author(s):  
Richard Frankham ◽  
Jonathan D. Ballou ◽  
Katherine Ralls ◽  
Mark D. B. Eldridge ◽  
Michele R. Dudash ◽  
...  
Keyword(s):  
Natural Selection ◽  
Genetic Differences ◽  
Outbreeding Depression ◽  
Isolated Populations ◽  
Large Populations

Crosses between populations within species sometimes result in reduced fitness, especially in F2 and later generations (outbreeding depression). The primary mechanisms causing outbreeding depression in crosses between populations are fixed chromosomal differences and adaptive genetic differences, especially for long-isolated populations. Outbreeding depression is usually observed after crossing populations with ploidy differences or fixed differences for translocations, inversions or centric fusions: the magnitudes are usually ploidy > translocations and monobrachial centric fusions > inversions and simple centric fusions. Populations adapted to different environments (but with the same karyotype) often exhibit outbreeding depression when crossed, especially in the F2 and later generations. Even if outbreeding depression occurs, it is often only temporary, as natural selection acts to remove it, especially in large populations.

scholarly journals Research on road engineering detection method based on GPR technology

2020 ◽  
Vol 165 ◽  
pp. 04014
Author(s):  
Liu Tao ◽  
Li Jia ◽  
Zheng Zhi-gang ◽  
Huang Zhi ◽  
Jiang Jian ◽  
...  
Keyword(s):  
Parameter Setting ◽  
Non Destructive Testing ◽  
Practical Application ◽  
Distribution Law ◽  
Destructive Testing ◽  
Road Engineering ◽  
The Road ◽  
Image Optimization ◽  
Testing Technology ◽  
Non Destructive

GPR is an effective non-destructive testing technology. This paper introduces its composition principle and operation method, explains the process of parameter setting and image optimization, obtains the dielectric constant of 10000 points, compares it with the density, and then obtains the uniformity distribution law of construction quality based on image. By calibrating the thickness of the road surface, the effective detection of road diseases can be realized, and the theoretical basis and practical application conditions of GPR technology can be clarified.

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