New and Re-Emerging Infectious Diseases in Sub-Saharan Africa

2017 ◽  
pp. 299-313 ◽  
Author(s):  
Alan Whiteside ◽  
Nick Zebryk
Keyword(s):  
Infectious Diseases ◽  
Emerging Infectious Diseases ◽  
Sub Saharan Africa ◽  
Sub Saharan

scholarly journals Emerging Infectious Diseases in Pregnant Women in a Non-Endemic Area: Almost One Out of Four Is at Risk

Pathogens ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 56
Author(s):  
Giulia Modi ◽  
Beatrice Borchi ◽  
Susanna Giaché ◽  
Irene Campolmi ◽  
Michele Trotta ◽  
...  
Keyword(s):  
Infectious Disease ◽  
At Risk ◽  
Infectious Diseases ◽  
Pregnant Women ◽  
Health Care Professionals ◽  
Emerging Infectious Diseases ◽  
Plasmodium Falciparum Malaria ◽  
Emerging Infectious Disease ◽  
Sub Saharan Africa ◽  
Sub Saharan

We report the results of a targeted testing strategy for five emerging infectious diseases (Chagas disease, human T-lymphotropic virus 1 infection, malaria, schistosomiasis, and Zika virus infection) in pregnant women accessing an Italian referral centre for infectious diseases in pregnancy for unrelated reasons. The strategy is based on a quick five-question questionnaire which allows the identification of pregnant women at risk who should be tested for a specific disease. One hundred and three (24%) out of 429 pregnant women evaluated in a 20 month period were at risk for at least one emerging infectious disease. Three (2.9%, all from sub-Saharan Africa) out of 103 at-risk women resulted in being affected (one case of Plasmodium falciparum malaria, two cases of schistosomiasis) and were appropriately managed. Prevalence of emerging infectious disease was particularly high in pregnant women from Africa (three out of 25 pregnant women tested, 12%). The proposed strategy could be used by health care professionals managing pregnant women in non-endemic setting, to identify those at risk for one of the five infection which could benefit for a targeted test and treatment.

scholarly journals Pre-Ebola virus disease laboratory system and related challenges in Liberia

2016 ◽  
Vol 5 (3) ◽  
Author(s):  
Stephen B. Kennedy ◽  
John B. Dogba ◽  
Christine L. Wasunna ◽  
Philip Sahr ◽  
Candace B. Eastman ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Ebola Virus ◽  
Virus Disease ◽  
Emerging Infectious Diseases ◽  
Health Facilities ◽  
Sub Saharan Africa ◽  
Ebola Virus Disease ◽  
Reference Laboratory ◽  
Laboratory System ◽  
Human Resource Capacity

Prior to the Ebola virus disease outbreak in Liberia, the laboratory system was duplicativefragmented and minimally coordinated. The National Reference Laboratory was conceptualisedto address the existing challenges by promoting the implementation of effective and sustainablelaboratory services in Liberia. However, in a resource-limited environment such as Liberiaprogress regarding the rebuilding of the health system can be relatively slow, while efforts tosustain the transient gains remain a key challenge for the Ministry of Health. In this paper, wedescribe the pre-Ebola virus disease laboratory system in Liberia and its prevailing efforts toaddress future emerging infectious diseases, as well as current Infectious diseases, all of whichare exacerbated by poverty. We conclude that laboratory and diagnostic services in Liberiahave encountered numerous challenges regarding its efforts to strengthen the healthcaredelivery system. These challenges include limited trained human resource capacity, inadequateinfrastructure, and a lack of coordination. As with most countries in sub-Saharan Africa, whencomparing urban and rural settings, diagnostic and clinical services are generally skewedtoward urban health facilities and private, faith-based health facilities. We recommend thatstructured policy be directed at these challenges for national institutions to develop guidelinesto improve, strengthen and sustain diagnostic and curative laboratory services to effectivelyaddress current infectious diseases and prepare for future emerging and re-emerging infectiousdiseases.

scholarly journals OPPORTUNISTIC INFECTIONS DIAGNOSED IN PATIENTS INFECTED WITH THE HUMAN IMMUNODEFICIENCY VIRUS (HIV) AT THE SERVICE OF INFECTIOUS DISEASES OF UHC (UNIVERSITY HOSPITAL CENTER) YALGADO OUÉDRAOGO, BURKINA FASO

2021 ◽  
pp. 1-2
Author(s):  
Savadogo M ◽  
Diallo I ◽  
Sondo K A
Keyword(s):  
Infectious Diseases ◽  
Hiv Infection ◽  
Opportunistic Infection ◽  
Antiretroviral Treatment ◽  
Opportunistic Infections ◽  
Sub Saharan Africa ◽  
University Hospital ◽  
Cross Sectional ◽  
Sub Saharan ◽  
Living With Hiv

Introduction: Sub-Saharan Africa remains one of the regions most affected by HIV infection with severe lethality.Most deaths of patients living with HIV are caused by opportunistic infections. Objective: to determine the prevalence of opportunistic infections among patients living with HIV in hospital serving infectious diseases of UHC YO of Ouagadougou. Patients and Methods:This is a cross-sectional descriptive study covering a 14-month period from 1 January 2017 to 28 February 2018. Included were all HIV-positive patients, hospitalized at the service of Infectious Diseases, in which an opportunistic infection was diagnosed on the basis of clinical and/or para-clinical arguments. Results: During the study period a total of 55 patients living with HIV were hospitalized in the infectious disease unit,35 of whom had at least one opportunistic infection or 63.6% of the patients.The average age of patients was 37 years with extremes of 18 and 66 years.Twenty-two patients were female versus 13 male, a sex ratio = 0.59. HIV1 was involved in 97% of patients.The mean TCD4 lymphocyte rate was 156 cell/mm3 with extremes of 7 and 718 cell/mm3.Tuberculosis and digestive mycosis were the most frequently diagnosed opportunistic infections. Opportunistic infection was the circumstance for HIV testing in two patients.She revealed immune restoration syndrome in two other patients.Nineteen patients were already on antiretroviral treatment upon admission to the service.Half of the patients on treatment were in therapeutic failure.The evolution was marked by 26.5% lethality. Conclusion:The frequency of opportunistic infections is high in patients living with HIV.Their prevention requires early detection of HIV infection and antiretroviral treatment.

scholarly journals The Burden of Infectious Diseases: A Trend Appraisal in Sub-Saharan Africa Regional Trade Blocs

2021 ◽  
Vol 2 (3) ◽  
pp. 104-122
Author(s):  
Olufunmilayo Olayemi Jemiluyi ◽  
Rebecca Folake Bank-Ola
Keyword(s):  
Human Immunodeficiency Virus ◽  
Infectious Diseases ◽  
Prevalence Rate ◽  
Sub Saharan Africa ◽  
Development Indicators ◽  
Trade Blocs ◽  
Immunodeficiency Virus ◽  
Two Measures ◽  
Sub Saharan ◽  
Southern Africa Development Community

Purpose: The study aimed at presenting a comparative appraisal of the trends of the two most prevalent infectious diseases bedeviling the region: human immunodeficiency virus (HIV) and tuberculosis (TB). Subject & Methods: Data on fourteen ECOWAS member countries and also fourteen member countries of the SADC bloc. This represents about 93.3% and 87.5% membership of the ECOWAS and SADC blocs respectively. Although the choice of sample size is determined largely by the availability of data, the choices were carefully made to maximize available observation. The data were sourced from World Development Indicators online database published by the World Bank. We use two measures of infectious diseases: the prevalence rate of human immunodeficiency virus and the incidence of tuberculosis. Results: The HIV prevalence rates and incidence of TB were uneven in the two selected trade blocs. The magnitude and the severity of the diseases varied. The burden of both diseases was higher for SADC and lesser for ECOWAS. The average prevalence rate of HIV in the SADC bloc over the study period was 600% of the prevalence rate in ECOWAS (SADC = 12.5%, ECOWAS = 2.1%). Likewise, in the same period, the average TB incidence per 100,000 people was 578.8 and 181.7 respectively in the SADC and ECOWAS blocs. Conclusions: The study finds that the magnitude and severity of the diseases vary widely between the Economic Community of West Africa States (ECOWAS) and the Southern Africa Development Community (SADC) trade blocs. And, while concerted efforts at curbing the diseases have yielded results, there is still much to be done in both blocs.

scholarly journals Pharmacogenomics for infectious diseases in sub-Saharan Africa: Successes and opportunities

2016 ◽  
Vol 9 ◽  
pp. 3-5 ◽  
Author(s):  
Mamoonah Chaudhry ◽  
Marco Alessandrini ◽  
Michael S. Pepper
Keyword(s):  
Infectious Diseases ◽  
Sub Saharan Africa ◽  
Sub Saharan

scholarly journals Infectious disease, development, and climate change: a scenario analysis

2007 ◽  
Vol 12 (5) ◽  
pp. 687-706 ◽  
Author(s):  
RICHARD S.J. TOL ◽  
KRISTIE L. EBI ◽  
GARY W. YOHE
Keyword(s):  
Climate Change ◽  
Infectious Disease ◽  
Infant Mortality ◽  
Infectious Diseases ◽  
Sub Saharan Africa ◽  
Absolute Poverty ◽  
Control Programs ◽  
Short Run ◽  
Sub Saharan

We study the effects of development and climate change on infectious diseases in Sub-Saharan Africa. Infant mortality and infectious disease are closely related, but there are better data for the former. In an international cross-section, per capita income, literacy, and absolute poverty significantly affect infant mortality. We use scenarios of these three determinants and of climate change to project the future incidence of malaria, assuming it to change proportionally to infant mortality. Malaria deaths will first increase, because of population growth and climate change, but then fall, because of development. This pattern is robust to the choice of scenario, parameters, and starting conditions; and it holds for diarrhoea, schistosomiasis, and dengue fever as well. However, the timing and level of the mortality peak is very sensitive to assumptions. Climate change is important in the medium term, but dominated in the long term by development. As climate can only be changed with a substantial delay, development is the preferred strategy to reduce infectious diseases even if they are exacerbated by climate change. Development can, in particular, support the needed strengthening of disease control programs in the short run and thereby increase the capacity to cope with projected increases in infectious diseases over the medium to long term. This conclusion must, however, be viewed with caution, because development, even of the sort envisioned in the underlying socio-economic scenarios, is by no means certain.

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