Does the Age of Onset Shape the Clinical Picture, Course and Consequences of Schizophrenia? Results from a Long-Term Epidemiological Study

2018 ◽  
pp. 29-54
Author(s):  
Heinz Häfner
Keyword(s):  
Epidemiological Study ◽  
Clinical Picture ◽  
Age Of Onset

scholarly journals Fibromuscular dysplasia with recurrence after “long-term” following percutaneous transcatheter renal angioplasty: two case reports with a review of 26 patients

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Shuntaro Oribe ◽  
Takafumi Toyohara ◽  
Eikan Mishima ◽  
Takehiro Suzuki ◽  
Koichi Kikuchi ◽  
...  
Keyword(s):  
Fibromuscular Dysplasia ◽  
Age Of Onset ◽  
Case Reports ◽  
Case Presentation ◽  
Renal Angioplasty ◽  
Long Term Follow Up ◽  
Percutaneous Transluminal Renal Angioplasty ◽  
The Difference

Abstract Background Fibromuscular dysplasia (FMD) often causes renal artery stenosis with renovascular hypertension. Recent clinical outcomes encourage percutaneous transluminal renal angioplasty (PTRA) to treat FMD; however, the necessary follow-up period remains unclear. Moreover, previous studies have not revealed the difference in the period until recurrence between two major types of FMD—multifocal and focal. Case presentation We describe two patients with multifocal FMD who developed hypertension during their teenage years and had recurrence of FMD > 10 years after PTRA. We further examined the types of FMD and age of onset in 26 patients who underwent PTRA. The period until recurrence of multifocal FMD was longer than that of focal FMD. Moreover, patients with early-onset multifocal FMD are likely to have a delayed recurrence after PTRA compared to other types. Conclusions Our report suggests that patients with multifocal FMD, especially those with onset at an early age, may need long-term follow-up for at least ≥ 10 years.

scholarly journals Epidemiological aspects ofCampylobacter jejunienteritis

1982 ◽  
Vol 89 (1) ◽  
pp. 163-170 ◽  
Author(s):  
G. Norkrans ◽  
Å. Svedhem
Keyword(s):  
Epidemiological Study ◽  
Campylobacter Jejuni ◽  
Family Members ◽  
Control Group ◽  
Household Members ◽  
Campylobacter Infection

SUMMARYAn epidemiological study onCampylobacter jejunienterocolitis was performed in an urban Swedish community. The study included 55 patients gathered during a six-month period. Forty-one of the 55 patients (75%) were infected outside Sweden. Campylobacter enterocolitis was rare among children within the country. Patients infected in Sweden had eaten chicken significantly more often than a corresponding control group. Seven out of nine chicken consuming campylobacter patients also had prepared the fresh chicken alone, and none of their family members became ill. Thus the preparation of food contaminated withCampylobacterseems to elevate the risk for contracting the disease. Sick household pets transmitted the campylobacter infection to two patients. Forty-six of the patients had a total of 85 close household members. Three definite secondary cases were found. There was no evidence of transmissionof Campylobacterby food prepared by two cooks who were working while still being asymptomatic excreters. Clinical reinfection withCampylobacterwas observed in one patient. No patients became long-term carriers ofCampylobacter.

ANOREXIA NERVOSA

PEDIATRICS ◽  
1982 ◽  
Vol 70 (4) ◽  
pp. 525-525
Author(s):  
Robert J. Haggerty
Keyword(s):  
Anorexia Nervosa ◽  
Early Onset ◽  
Age Of Onset ◽  
Outcome Studies ◽  
Psychosomatic Disorder ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Follow Up Studies

Anorexia nervosa is a serious psychosomatic disorder which most typically begins between 16 and 18 years of age. Clinicians have often held that early onset (eg, ages 11 to 15) is associated with a better outcome. This paper reviews the long-term outcome studies on anorexia nervosa and concludes that this contention is not supported by available data. The methodologies of seven outcome studies that focus on an early onset population are critiqued, and it is concluded that two methodologies are strong. Because of the increasing prevalence of anorexia nervosa, this once rare disorder can now be more easily investigated, and consequently better follow-up studies, which examine potential prognostic factors including age of onset, should be forthcoming.

Behcet Disease: Long-term Follow-up of Three Children and Review of the Literature

PEDIATRICS ◽  
1989 ◽  
Vol 83 (6) ◽  
pp. 986-992
Author(s):  
Yardena Rakover ◽  
Hanna Adar ◽  
Itamar Tal ◽  
Yaron Lang ◽  
Amos Kedar
Keyword(s):  
Fever Of Unknown Origin ◽  
Age Of Onset ◽  
Unknown Origin ◽  
Behçet Disease ◽  
Behcet Disease ◽  
Cns Involvement ◽  
Course Of Illness ◽  
Long Term Follow Up

Behcet disease is rare in children. There are only two reports of Behcet disease in childhood, describing seven patients. Three pediatric patients are described, in whom the age of onset ranged from 6 to 11 years. Aphthous stomatitis and arthritis were present in all of the patients; genital ulcers, iridocylitis, erythema nodosum, and CNS involvement were present in two patients. Other manifestations included Stevens-Johnson-like eruption, fever of unknown origin, and testicular involvement. All of the patients responded to glucocorticoids; two were also treated with colchicine and one was treated with chlorambucil. In two patients, follow-up of more than 10 years was done, with complete cure in one patient and benign course of illness in the other. Because of the rarity of the disease in childhood and the difficulty in making the diagnosis, there is not enough awareness by pediatricians concerning this disease.

The periodic syndrome in pediatric migraine sufferers

Cephalalgia ◽  
1983 ◽  
Vol 3 (1_suppl) ◽  
pp. 91-93 ◽  
Author(s):  
Giovanni Lanzi ◽  
Umberto Balottin ◽  
Elisa Fazzi ◽  
Francesca Burgio Rosano
Keyword(s):  
Motion Sickness ◽  
Age Of Onset ◽  
Periodic Syndrome ◽  
Age Group ◽  
Pediatric Age Group ◽  
Pediatric Migraine ◽  
Douleurs Abdominales ◽  
The Mean ◽  
Cyclic Vomiting

The present study takes into consideration some of the symptoms comprised in the Periodic Syndrome. These include motion-sickness, cyclic vomiting, recurrent abdominal pains and paroxysmal vertigo. Particular consideration is given to the chronological and long-term aspects of such symptoms. Among 247 migraine sufferers in the pediatric age group, 173 subjects who complained of at least one of these symptoms were chosen. Results of the data show that motion-sickness is the first to manifest itself (mean age of onset 2 years), and has a tendency to continue into the headache period; cyclic vomiting appears in the third year of life, and terminates sooner than the other symptoms. At the mean age of five years abdominal pains start, and at seven, paroxysmal vertigo. Headache is the final symptom in this group. The sequentiality of such disturbances in each subject leads to the assumption that the Periodic Syndrome is the expression of a single disorder which manifests itself polymorphously as a rather precisely timed process. Parmi les symptômes qui constituent le syndrome periodique de l'enfance, nous prenons en considération, dans cette étude, le mal d'auto, les vomissements cycliques, les douleurs abdominales récurrentes et les vertiges paroxystiques; nous en considérons particulièrement les aspects chronologiques et l'évolution à long terme. Il s'agit de 173 sujets, choisis parmi 247 migraineux en âge évolutif, qui ont présenté au moins un des symptômes que nous avons étudiés. L'analyse des données révèle que le mal d'auto est le premier qui se manifeste (au cours de la 2èMe année) et qu'il tend à continuer au-delà du moment où apparait la céphalée; au cours de la 3eMe année apparaissent les vomissements cycliques cui cessent plus tôt que les autres troubles; par la suite, vers l'âge de 5 ans, commencent les douleurs abdominales et vers 7 ans les vertiges paroxystiques; enfin apparait la céphalée. L'observation de la séquence de ces troubles chez les différents sujets nous amène à penser que le Syndrome périodique est l'expression d'un potentiel pathogène unique qui s'exprime à travers des aspects polymorphes selon une séquence temporelle assez précise. Fra i sintomi che costituiscono la Sindrome periodica dell'infanzia, nel presente studio prendiamo in esame il mal d'auto, i vomiti ciclici, i dolori addominali ricorrenti e le vertigini parossistiche, considerandone in particolare gli aspetti cronologici e di evoluzione a lungo termine. Si tratta di 173 soggetti, scelti fra 247 emicranici in età evolutiva che hanno lamentato almeno uno dei sintomi da noi considerati. Dall'analisi dei dati emerge che il mal d'auto si manifesta per primo (Il anno di vita) e tende a protrarsi oltre il momento d'insorgenza della cefalea; nel III anno compaiono i vomiti ciclici che si estinguono più precocemente degli altri disturbi; successivamente, verso i 5 anni, iniziano i dolori addominali e verso i 7 anni le vertigini parossistiche. Infine compare la cefalea. L'osservazione della sequenzialità di tali disturbi nei singoli soggetti ci fa pensare che la Sindrome periodica sia l'espressione di un unico potenziale patogeno che si estrinseca in aspetti polimorfi con una sequenza temporale abbastanza precisa.

scholarly journals The Association Between Age of Onset of Type 2 Diabetes with Long-term Risk of End Stage Kidney Disease: A National Registry Study

2020 ◽  
Author(s):  
Jedidiah I Morton ◽  
Danny Liew ◽  
Stephen P McDonald ◽  
Jonathan E Shaw ◽  
Dianna J Magliano
Keyword(s):  
Type 2 Diabetes ◽  
Kidney Disease ◽  
Cumulative Incidence ◽  
Age Of Onset ◽  
End Stage Kidney Disease ◽  
Onset Of Diabetes ◽  
End Stage ◽  
Effect Of Age

<b>Objective</b>: The long-term risk of end-stage kidney disease (ESKD) in type 2 diabetes is poorly described, as is the effect that younger age of diabetes onset has on this risk. Therefore, we aimed to estimate the effect of age of onset on the cumulative incidence of ESKD from onset of type 2 diabetes. <p><b>Research Design and Methods: </b>This study included 1,113,201 people with type 2 diabetes registered on the Australian National Diabetes Services Scheme (NDSS) followed from 2002 until 2013. The NDSS was linked to the Australia and New Zealand Dialysis and Transplant Registry and the Australian National Death Index. </p> <p><b>Results: </b>Between 2002 and 2013,<b> </b>there were 7,592 incident cases of ESKD during 7,839,075 person-years of follow up. In the first 10-15 years following onset of diabetes, the incidence of ESKD was highest in those with an older age of onset of diabetes, whereas over longer durations of diabetes the incidence of ESKD became higher in those with younger-onset diabetes. After 40 years of diabetes, the cumulative incidence of ESKD was 11.8% and 9.3% in those diagnosed with diabetes aged 10-29 and 30-39 years, respectively. When death from ESKD without renal replacement therapy was included, incidence of ESKD remained higher in older onset diabetes for the initial 20 years, with no clear effect of age thereafter.</p> <p><b>Conclusions: </b>The long-term risk of ESKD in type 2 diabetes is high, which disproportionately affects those with younger-onset of diabetes as they are more likely to survive to longer diabetes durations.</p>

Benign Paroxysmal Vertigo of Childhood: A Long-Term Follow-Up

Cephalalgia ◽  
1994 ◽  
Vol 14 (6) ◽  
pp. 458-460 ◽  
Author(s):  
G Lanzi ◽  
U Balottin ◽  
E Fazzi ◽  
M Tagliasacchi ◽  
M Manfrin ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Age Of Onset ◽  
Clinical Aspects ◽  
Migrainous Vertigo ◽  
Long Term Follow Up

We examined clinical aspects of Benign Paroxysmal Vertigo (BPV) in infancy and its most frequent differential diagnosis, in particular analogies and differences with forms of “migrainous vertigo” (MV) of later onset. During a long-term follow-up of 7 cases of BPV, diagnosed according to the Basser criteria, 5 of 7 BPV cases spontaneously resolved and 6 of 7 patients later developed migraine and other migraine-related symptoms. This course differs from that described for MV only in the age of onset of headache and in the chronological relationship with vertigo. The authors suggest that BPV can be interpreted as a migraine precursor and MV as a migraine equivalent.

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