Current Analytical Methods for Qualitative and Quantitative Measurement of d-Xylitol

D-Xylitol ◽  
2012 ◽  
pp. 245-263
Author(s):  
Zhongqi Jiang ◽  
Samuel Amartey ◽  
Zi-Hua Jiang ◽  
Wensheng Qin
Keyword(s):  
Analytical Methods ◽  
Quantitative Measurement ◽  
Qualitative And Quantitative

scholarly journals Molecular Species of the Alcohol Biomarker Phosphatidylethanol in Human Blood Measured by LC-MS

2009 ◽  
Vol 55 (7) ◽  
pp. 1395-1405 ◽  
Author(s):  
Anders Helander ◽  
Yufang Zheng
Keyword(s):  
Fatty Acid ◽  
Human Blood ◽  
Molecular Species ◽  
Quantitative Measurement ◽  
Selected Ion Monitoring ◽  
Blood Samples ◽  
Qualitative And Quantitative ◽  
Ms Analysis ◽  
Alcohol Biomarker ◽  
Product Ions

Abstract Background: The alcohol biomarker phosphatidylethanol (PEth) comprises a group of ethanol-derived phospholipids formed from phosphatidylcholine by phospholipase D. The PEth molecular species have a common phosphoethanol head group onto which 2 fatty acid moieties are attached. We developed an electrospray ionization (ESI) LC-MS method for qualitative and quantitative measurement of different PEth species in human blood. Methods: We subjected a total lipid extract of whole blood to HPLC gradient separation on a C4 column and performed LC-ESI-MS analysis using selected ion monitoring of deprotonated molecules for the PEth species and phosphatidylpropanol (internal standard). Identification of individual PEth species was based on ESI–tandem mass spectrometry (MS/MS) analysis of product ions. Results: The fatty acid moieties were the major product ions of PEth, based on comparison with PEth-16:0/16:0, 18:1/18:1, and 16:0/18:1 reference material. For LC-MS analysis of different PEth species in blood, we used a calibration curve covering 0.2–7.0 μmol/L PEth-16:0/18:1. The lower limit of quantitation of the method was <0.1 μmol/L, and intra- and interassay CVs were <9% and <11%. In blood samples collected from 38 alcohol patients, the total PEth concentration ranged between 0.1 and 21.7 μmol/L (mean 8.9). PEth-16:0/18:1 and 16:0/18:2 were the predominant molecular species, accounting for approximately 37% and 25%, respectively, of total PEth. PEth-16:0/20:4 and mixtures of 18:1/18:1 plus 18:0/18:2 (not separated using selected ion monitoring because of identical molecular masses) and 16:0/20:3 plus 18:1/18.2 made up approximately 13%, 12%, and 8%. Conclusions: This LC-MS method allows simultaneous qualitative and quantitative measurement of several PEth molecular species in whole blood samples.

A review and preview of developments in the measurement of sociability

2020 ◽  
Vol 84 (1) ◽  
pp. 79-101
Author(s):  
Nicholas Boswell ◽  
Jian Cao ◽  
W. Jackeline Torres ◽  
Margaret Beier ◽  
Ashutosh Sabharwal ◽  
...  
Keyword(s):  
Mental Health ◽  
Social Interactions ◽  
Quantitative Measurement ◽  
Measurement Methods ◽  
Self Report ◽  
Physical And Mental Health ◽  
Qualitative And Quantitative ◽  
Social Patterns ◽  
Advantages And Disadvantages ◽  
Mental Health Effects

Sociability is a complex, multifactorial trait. Its importance is underscored by a multitude of negative physical and mental health effects related to loneliness and social isolation. However, current measures of sociability primarily rely on subjective recall and self- report, which have inherent weaknesses and limitations. Although objective and automatic measurements could help to avoid some of these issues, they are still in early stages of development. In this article, the authors review past and present methods of measuring sociability and social interactions. This encompasses both subjective and objective subsets of qualitative and quantitative measurement modalities to gain a broader, more accurate perspective on sociability. Through an analysis of advantages and disadvantages of measurement methods within these categories, a foundational knowledge of sociability measurement can be understood. Utilizing current technology and research methods holds promise to more accurately represent individuals' social networks and social patterns.

Sample preparation approaches for qualitative and quantitative analysis of lipid-derived electrophile modified proteomes by mass spectrometry

2020 ◽  
Vol 16 (6) ◽  
pp. 511-520
Author(s):  
Wenjuan Yuan ◽  
Jun Wang ◽  
Ying Zhang ◽  
Haojie Lu
Keyword(s):  
Mass Spectrometry ◽  
Quantitative Analysis ◽  
Sample Preparation ◽  
Analytical Methods ◽  
Qualitative And Quantitative Analysis ◽  
Qualitative And Quantitative

MS-based analytical methods of lipid-derived electrophile modified proteome are discussed in this review.

scholarly journals Qualitative and quantitative measurement of the anterior and posterior meniscal root attachments of the New Zealand white rabbit

2016 ◽  
Vol 3 (1) ◽  
Author(s):  
David Civitarese ◽  
Tammy L. Haut Donahue ◽  
Christopher M. LaPrade ◽  
Adriana J. Saroki ◽  
Samuel G. Moulton ◽  
...  
Keyword(s):  
New Zealand ◽  
Quantitative Measurement ◽  
Zealand White Rabbit ◽  
Qualitative And Quantitative ◽  
New Zealand White Rabbit ◽  
Meniscal Root

scholarly journals Recent innovations in analytical methods for the qualitative and quantitative assessment of lignin

2015 ◽  
Vol 49 ◽  
pp. 871-906 ◽  
Author(s):  
Jason S. Lupoi ◽  
Seema Singh ◽  
Ramakrishnan Parthasarathi ◽  
Blake A. Simmons ◽  
Robert J. Henry
Keyword(s):  
Analytical Methods ◽  
Quantitative Assessment ◽  
Qualitative And Quantitative
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