Design and Development of a Piezoelectrically Actuated Micropump for Drug Delivery Application

Author(s):  
Paul Braineard Eladi ◽  
Dhiman Chatterjee ◽  
Amitava DasGupta
Author(s):  
Bibhu Prasad Panda ◽  
N.S Dey ◽  
M.E.B. Rao

Over the past few decades, there has been an increased interest for innovative drug delivery systems to improve safety, efficacy and patient compliance, thereby increasing the product patent life cycle. The discovery and development of new chemical entities is not only an expensive but also time consuming affair. Hence the pharmaceutical industries are focusing on the design and development of innovative drug delivery systems for existing drugs. One such delivery system is the fast disintegrating oral film, which has gained popularity among pediatric and geriatric patients. This fast disintegrating film with many potential benefits of a fast disintegrating tablet but devoid of friability and risk of choking is more acceptable to pediatric and geriatric patients. Formulation of fast disintegrating film can be achieved by various techniques, but common methods of preparation include spraying and casting. These film forming techniques use hydrophilic film former in combination with suitable excipients, which allow the film to disintegrate or dissolve quickly in the mouth within a few seconds without the administration of water. In view of the advantages of the fast disintegrating films over the fast disintegrating tablets and other dosage forms, it has the potential for commercial exploitation. The oral film dosage form not only has certain advantages of other fast disintegrating systems but also satisfies the unmet needs of the market. The present review emphasizes on the potential benefits, design and development of robust, stable, and innovative orally fast- disintegrating films and their future scenarios on a global market as a pharmaceutical dosage form.  


2011 ◽  
Vol 1 (2) ◽  
pp. 112 ◽  
Author(s):  
Jaydeep Patel ◽  
Garala Kevin ◽  
Anjali Patel ◽  
Mihir Raval ◽  
Navin Sheth

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Olalekan A. Balogun-Agbaje ◽  
Olubusola A. Odeniyi ◽  
Michael A. Odeniyi

Abstract Background Poly-γ-glutamic acid (γ-PGA) is a biopolymer of microbial origin, consisting of repeating units of l-glutamic acid and/or D-glutamic acid. The biopolymer has found use in the fields of agriculture, food, wastewater, and medicine, owing to its non-toxic, biodegradable, and biocompatible properties. Due to its biodegradability, γ-PGA is being tipped to dislodge synthetic plastics in drug delivery application. High cost of production, relative to plastics, is however a clog in the wheel of achieving this. Main body of abstract This review looked at the production, nanoparticles fabrication, and drug delivery application of γ-PGA. γ-PGA production optimization by modifying the fermentation medium to tailor towards the production of desirable polymer at reduced cost and techniques for the formulation of γ-PGA nanoparticle as well as its characterization were discussed. This review also evaluated the application of γ-PGA and its nanoparticles in the delivery of drugs to action site. Characterization of γ-PGA and its nanoparticles is a crucial step towards determining the applicability of the biopolymer. γ-PGA has been used in the delivery of active agents to action sites. Conclusion This review highlights some of the efforts that have been made in the appraisal of γ-PGA and its nanoparticles for drug delivery. γ-PGA is a candidate for future extensive use in drug delivery.


2013 ◽  
Vol 5 (14) ◽  
pp. 6484-6493 ◽  
Author(s):  
Shaheena Parween ◽  
Ashraf Ali ◽  
Virander S. Chauhan

2006 ◽  
Vol 7 (3) ◽  
Author(s):  
Pradip Kumar Ghosh ◽  
Rita J. Majithiya ◽  
Manish L. Umrethia ◽  
Rayasa S. R. Murthy

2018 ◽  
Vol 34 (3) ◽  
pp. 117-125 ◽  
Author(s):  
Vishal Vijay Pande ◽  
Komal Sadashiv Jadhav ◽  
Mahendra Ashok Giri ◽  
Prakash Namdeo Kendre ◽  
Somanth Kedarling Vibhute ◽  
...  

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