An Inventory Policy for Maximum Fixed Life-Time Item with Back Ordering and Variable Demand Under Two Levels Order Linked Trade Credits

2021 ◽  
pp. 61-75
Author(s):  
Mrudul Y. Jani ◽  
Nita H. Shah ◽  
Urmila Chaudhari
Keyword(s):  
Life Time ◽  
Variable Demand ◽  
Inventory Policy ◽  
Trade Credits

Inventory policy of a deteriorating item with variable demand under trade credit period

2014 ◽  
Vol 76 ◽  
pp. 75-88 ◽  
Author(s):  
Partha Guchhait ◽  
Manas Kumar Maiti ◽  
Manoranjan Maiti
Keyword(s):  
Trade Credit ◽  
Variable Demand ◽  
Inventory Policy ◽  
Credit Period

Optimal Credit Period and Lot-Size for Deteriorating Items With Fixed Life Time and Trade Credits

2018 ◽  
pp. 44-57
Author(s):  
Dushyantkumar G. Patel ◽  
Nita H. Shah ◽  
Digeshkumar B. Shah
Keyword(s):  
Default Risk ◽  
Life Time ◽  
Inventory Model ◽  
Sensitivity Analyses ◽  
Profit Function ◽  
Lot Size ◽  
Credit Period ◽  
Trade Credits ◽  
Total Profit ◽  
Prime Objective

To boost the sale is the prime objective for promoters. For this purpose, they generally allow credit period. In this article, we have considered an inventory model in which supplier gives credit period to retailer and to increase the sale, retailer passes it to end customers. This phenomenon is known as two level trade credits. By allowing credit period we may encounter with the issue of default risk which has been taken care of while calculating profit function for the system. Also, each and every inventory product gets deteriorated over the time as per its nature and such deteriorating products have its maximum life time as well. The present inventory model deals with such products. Quadratic demand is discussed here which is suitable for the products for which demand increases initially and after sometimes it shows decreasing pattern. Finally, retailer's total profit is maximized with respect to credit period and cycle time. Numerical examples are given to validate the model. Sensitivity analyses are done to filter significant inventory parameters.

scholarly journals Effect of Inflation and Variable Holding Cost on Life Time Inventory Model with Multi Variable Demand and Lost Sales

2020 ◽  
Vol 8 (5) ◽  
pp. 5513-5519
Keyword(s):  
Life Time ◽  
Inventory Model ◽  
Selling Price ◽  
Variable Demand ◽  
Time Value Of Money ◽  
Time Value ◽  
Demand Rate ◽  
Holding Cost ◽  
Variable Holding Cost ◽  
Value Of Money

This paper analyses an inventory model for life time declining item with variable carrying rate and multi variable demand rate. In this model, the consumption rate depending on selling price as well as displayed stock and when the shortage occurs only on selling price of the manufactured article. Moreover, in this model the deterioration is taken time dependent, which is non-instantaneous in nature. In this study we also consider a very realistic concept of variable carrying rate in which the carrying rate per unit per period to be a function of the time used up in storage. This model is firm for minimizing the average total rate per unit period under the effect of inflation and time value of money. Numerical examples are used to illustrate the wished-for model and a sensitivity analysis is passed out to study the effect of different constraints

SEM and Auger microanalysis studies of Cu-Be dynode surfaces at each activation condition

1978 ◽  
Vol 36 (1) ◽  
pp. 524-525
Author(s):  
T. Koshikawa ◽  
Y. Fujii ◽  
E. Sugata ◽  
F. Kanematsu
Keyword(s):  
Electron Emission ◽  
Secondary Electron ◽  
Secondary Electron Emission ◽  
Life Time ◽  
Activation Process ◽  
Beam Diameter ◽  
Activation Temperature ◽  
Electron Multiplier ◽  
Activation Condition ◽  
Activation Conditions

The Cu-Be alloys are widely used as the electron multiplier dynodes after the adequate activation process. But the structures and compositions of the elements on the activated surfaces were not studied clearly. The Cu-Be alloys are heated in the oxygen atmosphere in the usual activation techniques. The activation conditions, e.g. temperature and O2 pressure, affect strongly the secondary electron yield and life time of dynodes.In the present paper, the activated Cu-Be dynode surfaces at each condition are investigated with Scanning Auger Microanalyzer (SAM) (primary beam diameter: 3μmϕ) and SEM. The commercial Cu-Be(2%) alloys were polished with Cr2O3 powder, rinsed in the distilled water and set in the vacuum furnance.Two typical activation condition, i.e. activation temperature 730°C and 810°C in 5x10-3 Torr O2 pressure were chosen since the formation mechanism of the BeO film on the Cu-Be alloys was guessed to be very different at each temperature from the results of the secondary electron emission measurements.

Negative Life Events Associated With Deliberate Self-Harm in an African Population in Uganda

Crisis ◽  
2005 ◽  
Vol 26 (1) ◽  
pp. 4-11 ◽  
Author(s):  
E. Kinyanda ◽  
H. Hjelmeland ◽  
S. Musisi
Keyword(s):  
Life Events ◽  
Negative Life Events ◽  
Life Time ◽  
Later Life ◽  
Dose Effect ◽  
Deliberate Self Harm ◽  
Time Period ◽  
Significant Difference ◽  
Self Harm ◽  
Suicide Interventions

Abstract. Negative life events associated with deliberate self-harm (DSH) were investigated in an African context in Uganda. Patients admitted at three general hospitals in Kampala, Uganda were interviewed using a Luganda version (predominant language in the study area) of the European Parasuicide Study Interview Schedule I. The results of the life events and histories module are reported in this paper. The categories of negative life events in childhood that were significantly associated with DSH included those related to parents, significant others, personal events, and the total negative life events load in childhood. For the later-life time period, the negative life events load in the partner category and the total negative life events in this time period were associated with DSH. In the last-year time period, the negative life events load related to personal events and the total number of negative life events in this time period were associated with DSH. A statistically significant difference between the cases and controls for the total number of negative life events reported over the entire lifetime of the respondents was also observed, which suggests a dose effect of negative life events on DSH. Gender differences were also observed among the cases. In conclusion, life events appear to be an important factor in DSH in this cultural environment. The implication of these results for treatment and the future development of suicide interventions in this country are discussed.

Inactivation of Factor XIa in Vivo: Studies in Chimpanzees and in Humans

1996 ◽  
Vol 76 (04) ◽  
pp. 549-555 ◽  
Author(s):  
Walter A Wuillemin ◽  
C Erik Hack ◽  
Wim K Bleeker ◽  
Bart J Biemond ◽  
Marcel Levi ◽  
...  
Keyword(s):  
Antithrombin Iii ◽  
Life Time ◽  
In Vivo Studies ◽  
Clinical Samples ◽  
Plasma Samples ◽  
C1 Inhibitor ◽  
Elimination Kinetics ◽  
Factor Xia ◽  
Best Parameter

SummaryC1-inhibitor (C1Inh), antithrombin III (ATIII), α1-antitrypsin (a1AT), and α2-antiplasmin (a2AP) are known inhibitors of factor XIa (FXIa). However, their precise contribution to FXIa inactivation in vivo is not known. We investigated FXIa inactivation in chimpanzees and assessed the contribution of these inhibitors to FXIa inactivation in patients with presumed FXI activation.Chimpanzees were infused with FXIa and the various FXIa-FXIa inhibitor complexes formed were measured. Most of FXIa was complexed to C1Inh (68%), followed by a2AP (13%), a1AT (10%), and ATIII (9%). Analysis of the plasma elimination kinetics revealed a half-life time of clearance (t1/2) for the FXIa-FXIa inhibitor complexes of 95 to 104 min, except for FXIa-a1AT, which had a t1/2 of 349 min. Due to this long t1/2, FXIa-a1AT complexes were predicted to show the highest levels in plasma samples from patients with activation of FXI. This was indeed shown in patients with disseminated intravascular coagulation, recent myocardial infarction or unstable angina pectoris. We conclude from this study that in vivo C1Inh is the predominant inhibitor of FXIa, but that FXIa-a1 AT complexes due to their relatively long t1/2 may be the best parameter to assess FXI activation in clinical samples.

Covalent Complexes Between Low Molecular Weight Heparin Fragments and Antithrombin III – Inhibition Kinetics and Turnover Parameters

1983 ◽  
Vol 49 (02) ◽  
pp. 109-115 ◽  
Author(s):  
M Hoylaerts ◽  
E Holmer ◽  
M de Mol ◽  
D Collen
Keyword(s):  
Molecular Weight ◽  
Half Life ◽  
Low Molecular Weight Heparin ◽  
Antithrombin Iii ◽  
Factor Xa ◽  
Life Time ◽  
Low Molecular Weight ◽  
High Affinity ◽  
Plasma Half Life ◽  
Covalent Complex

SummaryTwo high affinity heparin fragments (A/r 4,300 and M, 3,200) were covalently coupled to antithrombin III (J. Biol. Chem. 1982; 257: 3401-3408) with an apparent 1:1 stoichiometry and a 30-35% yield.The purified covalent complexes inhibited factor Xa with second order rate constants very similar to those obtained for antithrombin III saturated with these heparin fragments and to that obtained for the covalent complex between antithrombin III and native high affinity heparin.The disappearance rates from plasma in rabbits of both low molecular weight heparin fragments and their complexes could adequately be represented by two-compartment mammillary models. The plasma half-life (t'/j) of both low Afr-heparin fragments was approximately 2.4 hr. Covalent coupling of the fragments to antithrombin III increased this half-life about 3.5 fold (t1/2 ≃ 7.7 hr), approaching that of free antithrombin III (t1/2 ≃ 11 ± 0.4 hr) and resulting in a 30fold longer life time of factor Xa inhibitory activity in plasma as compared to that of free intact heparin (t1/2 ≃ 0.25 ± 0.04 hr).

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