Effect of galanthamine on reparative regeneration of muscles in tailless amphibians

1972 ◽  
Vol 73 (1) ◽  
pp. 81-83
Author(s):  
T. E. Pavlova
Keyword(s):  
Reparative Regeneration ◽  
Tailless Amphibians

Influence of Bivalos on reparative regeneration of the bone tissue: data of experimental and clinical studies

2012 ◽  
Vol 0 (1) ◽  
pp. 5
Author(s):  
Vladyslav Povorozniuk ◽  
Mykola Korzh ◽  
Natalya Grigoryeva ◽  
Volodymyr Klimovitskiy
Keyword(s):  
Bone Tissue ◽  
Clinical Studies ◽  
Reparative Regeneration

Vitamin D Effects on Guided Bone Regeneration and Osseointegration of Dental Implants (Literature Review)

2020 ◽  
Vol 75 (5) ◽  
pp. 552-560
Author(s):  
Sergey Yu. Ivanov ◽  
Svetlana Yu. Kalinchenko ◽  
Nidjat A. Guseynov ◽  
Aleksander A. Muraev ◽  
Aigul Т. Safi ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Tissue ◽  
Dental Implants ◽  
Scientific Data ◽  
Reparative Regeneration ◽  
Jaw Bone ◽  
Dental Implantation ◽  
Oral Reconstruction ◽  
Phosphate Exchange ◽  
Regeneration Of Bone

Background.Due to the prevalence of Vitamin D deficiency as well as the frequency of reconstructive surgical interventions followed by dental implantation, the issue arises concerning the effect of Vitamin D on reparative regeneration of bone and osseointegration of dental implants.The purpose using literature data we are conducting an impact assessment of vitamin D on reparative regeneration of bone tissue, in particular, after oral reconstruction surgeries and dental implantation.Methods.Retrieval, systematization and analysis of scientific data on application of vitamin D supplementation and its effect on reparative regeneration of jaw bone tissue.The conclusions.For the most part, the positive effect exerted on reparative regeneration of jaw bone tissue and osseointegration of dental implants is due to the role of vitamin D in physiological processes evolving in bone tissue, namely maintenance of calcium and phosphate exchange through intestinal absorption and TNF, RANKL (Receptor activator of nuclear factor kappa-B ligand) and consequently differentiation of precursors to osteoclasts into osteoclasts through VDR stimulation (VitaminD Receptor) receptors for further osteogenesis. Also, according to literature data, FGF23 (Fibroblast Growth Factor) protein is a marker of osteoblasts differentiation into osteocytes, it is also known that FGF23 and 1,25(ОН)2D3 are genetically related. FGF23 is the main regulator of both phosphate exchange in bones and metabolism of vitamin D and its metabolites. Besides, indirect anti-inflammatory effect has been observed thanks to inhibition of pro-inflammatory cytokine secretion. Taking into account the abovementioned data, of particular relevance is the definition of serum concentration 25(ОН)D and development of schemes of vitamin D level pre-surgery correction in patients, who have to undergo oral reconstruction surgeries and dental implantation. Mass spectrometry is a promising diagnostic method for determining the level of vitamin D in a body, as it allows to identify the actual amount of vitamin D free from admixture of other steroid hormones. The introduction of this method into clinical practice will allow to monitor the level of vitamin D in patients, receiving reconstructive and rehabilitative treatment.

Dynamics of indicators of reparative regeneration of the oral mucosa in patients with lichen planus

2019 ◽  
Vol 24 (3) ◽  
pp. 264-268
Author(s):  
I. V. Firsova ◽  
S. V. Poroiskiy ◽  
Yu. A. Makedonova ◽  
Yu. M. Fedotova
Keyword(s):  
Lichen Planus ◽  
Oral Mucosa ◽  
Laboratory Data ◽  
Reparative Regeneration ◽  
Layer By Layer ◽  
Qualitative And Quantitative Analysis ◽  
Cytological Examination ◽  
Sandwich Technique ◽  
Ulcerative Lesions ◽  
Chronic Course

Relevance: red lichen planus refers to a long, protracted disease with a chronic course. There are a lot of root causes, it is quite difficult to differentiate them. Therefore, pharmacotherapy of this pathology is reduced to the appointment of local drugs that have only symptomatic effects that help accelerate the healing of the oral mucosa.Purpose – to study reparative regeneration based on the analysis of clinical and cytological examination on the background of the appointment of various methods of pharmacotherapy.Materials and methods: all patients were divided into two groups using simple randomization: in patients of the first group, betamethasone B was used to treat erosive-ulcerative lesions, which were delivered to the lesion using Tisol, which has conductive transcutaneous activity, using the sandwich technique. The second group of patients used the drug delivery system in the form of a film, which fixed betamethasone B in the lesion area.Results: were evaluated before treatment, on day 7 and 14. The area and intensity of healing of the oral mucosa were determined, a qualitative and quantitative analysis of cytograms was carried out, which characterizes the dynamics of reparative regeneration of erosions and ulcers.Conclusion: based on the obtained clinical and laboratory data, it can be concluded that it is advisable to include betamethasone applications in the pharmacotherapy of patients with erosive and ulcerative forms of lichen planus. However, preference should be given to the method of layer-by-layer application of betamethasone B in combination with Tezol.  

Reparative regeneration of rat skin under influence of hollow cathode lamp (HCL) with manganese and copper line spectrum emission

2010 ◽  
Vol 4 (3) ◽  
pp. 234-239
Author(s):  
V. I. Melnikova ◽  
M. S. Izvolskaia ◽  
S. N. Voronova ◽  
M. M. Sharipova ◽  
E. M. Rukin ◽  
...  
Keyword(s):  
Hollow Cathode ◽  
Reparative Regeneration ◽  
Line Spectrum ◽  
Rat Skin ◽  
Hollow Cathode Lamp ◽  
Copper Line

scholarly journals THE EFFECTS OF ILLUMINATION ON THE EARLY DEVELOPMENT OF AMPHIBIANS (AMPHIBIA: ANURA AND CAUDATA)

2018 ◽  
Vol 15 (30) ◽  
pp. 152-159
Author(s):  
A. B. RUCHIN
Keyword(s):  
Survival Rate ◽  
Early Development ◽  
Rana Arvalis ◽  
Low Light ◽  
Amphibian Species ◽  
Triturus Cristatus ◽  
Lissotriton Vulgaris ◽  
Light Intensities ◽  
Tailless Amphibians

The effects of illumination on the early development of four amphibian species — Lissotriton vulgaris (Linnaeus, 1758), Triturus cristatus (Laurenti, 1768), Rana arvalis (Nilsson, 1842), and R. temporaria (Linnaeus, 1758) — have been studied. In general, the rate of their early development is rather independent of illumination. The eggs of tailless amphibians develop almost similarly under any illumination conditions, whereas the eggs of tailed amphibians better develop at an illumination of 700 lx. Illumination mainly influences the survival rate of embryos and prolarvae, which increases at low light intensities and decreases in the dark. Possible mechanisms and causes underlying the observed facts are discussed.

scholarly journals Determination of the activity of pyruvate kinase isoforms in normal conditions, in toxic liver damage and during the process of its regeneration

2021 ◽  
pp. 116-123
Author(s):  
A. G. Skuratov ◽  
A. N. Lyzikov ◽  
A. S. Shaforost ◽  
A. A. Zyatskov ◽  
N. M. Golubykh
Keyword(s):  
Pyruvate Kinase ◽  
Liver Damage ◽  
Intraperitoneal Administration ◽  
Mechanical Damage ◽  
Elisa Test ◽  
Reparative Regeneration ◽  
Laboratory Animals ◽  
Toxic Damage ◽  
Toxic Liver Damage

Objective. To evaluate the activity of pyruvate kinase (PK) isoforms in normal conditions, in toxic damage of the liver and during its regeneration.Materials and methods. An experimental study was carried out on 45 Wistar rats. Toxic liver damage was induced by the intraperitoneal administration of carbon tetrachloride. Mechanical damage was simulated by the surgical resection of the liver. The levels of PK isoforms R/L and M in the blood serum and liver tissue of the laboratory animals were measured with an ELISA test.Results. It has been found that the level of PK isoform M signifcantly increases in chronic toxic liver damage, which may indicate the activation of the processes of liver cell proliferation in response to the damaging effect of hepatotoxin (Mann-Whitney U Test: Z = 2.143; p = 0.032). After liver resection, the level of PK R/L, which characterizes the activation of glycolysis, increased and the level of pyruvate kinase M increased signifcantly, which reflected the processes of reparative regeneration in the liver.Conclusion. The serum level of PK isoforms may be used as a laboratory criterion for the activity of reparative regeneration processes, which can be used to evaluate the reparative potential of the liver in case of toxic or mechanical damage, as well as in chronic diffuse diseases.

scholarly journals INFLUENCE OF DISTURBED CONDITIONS OF REPARATIVE REGENERATION OF BONE TISSUE ON THE DYNAMICS OF THYROID HORMONES

2016 ◽  
Vol 1 (4) ◽  
pp. 109-114 ◽  
Author(s):  
Курганский ◽  
Ilya Kurganskiy ◽  
Родионова ◽  
Lyubov Rodionova ◽  
Зарицкая ◽  
...  
Keyword(s):  
Thyroid Hormones ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Normal Values ◽  
Gradual Increase ◽  
Reparative Regeneration ◽  
Bone Tissue Regeneration ◽  
Regeneration Of Bone Tissue ◽  
Peripheral Conversion ◽  
Regeneration Of Bone

Managing bone tissue regeneration is a key problem in traumatology and orthopedics. The researches proved that thyroid hormones affect hemostasis and reparative regeneration of bone tissue favorably and promote osteogenesis and bone consolidation.The aim of this research is to study the influence of disturbed reparative regeneration on the concentration of thyroid hormones in blood in the dynamics. Experimental research on rabbits (n=12) with modelling of disturbed reparative regeneration revealed disorder in thyroid hormones synthesis and different directions of T3 and unbound T3 production on the 35th day when the maxi-mum decrease of T3 (2times) and unbound T3 (1.5times) compared to normal values was registered. The analysis of production of T4 and unbound T4 revealed suppression of the values from the 1st to 50th day and gradual increase in unbound T4 from the 50th day. The most significant manifestation of thyroid gland reaction on the disturbed reparative regeneration of shin bones was the decrease in T3 and peripheral conversion of thyroid hormones up to 50th day with formation of false joint in these terms.

scholarly journals THE EFFECT OF ENTEROSORPTION AND INTRATISSULAR ELECTROFORESIS OF ANTIBACTERIAL DRUGS ON PROGRESS OF BURN DISEASE

2020 ◽  
pp. 188-192
Author(s):  
B. V. Petriuk ◽  
I. I. Blуk ◽  
О. V. Rоtаr ◽  
L. P. Khomko ◽  
T. A. Petriuk ◽  
...  
Keyword(s):  
Electrical Conductivity ◽  
Thermal Damage ◽  
Positive Influence ◽  
Reparative Regeneration ◽  
Comprehensive Treatment ◽  
Antibacterial Drugs ◽  
Average Mass ◽  
Thermal Burns ◽  
Burn Disease ◽  
Extensive Burns

Summary. The purpose of our research was to explore the appropriateness of combined usage of enterosorption amplification and intratissular electrophoresis (ITE) of antibiotics in cases of substantial thermal burns. The effect of intratissular electrophoresis (ITE) of antibacterial drugs and enterosorption was studied in 22 patients with dermal thermal burns from 28 to 54 % of their body surface. ITE of antibiotics started from the 3–4 day applying the direct current with density 0,03-0,05 mAh/cm² for 60 min. by the «POTOK-1» device. The authors determined the intoxication degree based on the leukocyte index, the number of average mass molecules and blood plasma electrical conductivity. Also, they observed the course of wound process, conducted bacteriological and cytological researches of the burn wounds in dynamics on 1–3, 6–7, 13–14 and 19–21 days of the burn disease progress. It was found that enterosorption usage in the comprehensive treatment of burn disease allows not only to reduce the level of endogenous intoxication but also to provide an indirect optimizing impact on the progressing of the wound process in the zone of thermal damage, stimulate the reparative regeneration. In the cases with extensive burns, combined usage of the enterosorption detoxification by Enterosgel with the ITE of antibacterial drugs contribute more qualitative positive influence on the wound process and burn disease in general.

Transcranial electrostimulation activates reparative regeneration and the insulin-producing function of pancreatic B-cells in alloxan diabetes in rats

2007 ◽  
Vol 37 (4) ◽  
pp. 341-347
Author(s):  
V. P. Lebedev ◽  
S. V. Bilichenko ◽  
N. É. Ordyan ◽  
S. G. Pivina ◽  
S. P. Nechiporenko ◽  
...  
Keyword(s):  
B Cells ◽  
Alloxan Diabetes ◽  
Reparative Regeneration ◽  
Transcranial Electrostimulation ◽  
Pancreatic B Cells
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