Changes in serum lysozyme activity in terminal states caused by blood loss

1975 ◽  
Vol 80 (5) ◽  
pp. 1300-1302
Author(s):  
S. K. Anan'eva
1978 ◽  
Vol 71 (9) ◽  
pp. 1109-1111 ◽  
Author(s):  
N. LEVY ◽  
R. G. GIBSON ◽  
A. A. MIHAS ◽  
B. I. HIRSCHOWITZ

1978 ◽  
Vol 24 (1) ◽  
pp. 74-79 ◽  
Author(s):  
G Horpacsy ◽  
J Zinsmeyer ◽  
K Schröder ◽  
M Mebel

Abstract We investigated changes in lysozyme activity in serum and urine of kidney-transplant patients, and found that the production and catabolism of lysozyme in such patients differs markedly from that in normal subjects. Resumption of graft function decreases the high serum lysozyme activity by increasing the rate of catabolism in the transplant; at the same time, however, the production is inhibited by therapy with azathioprine. Changes in serum lysozyme activity correlate well with leukocyte count; thus its determination might be useful in monitoring immunosuppression. The urinary excretion of the enzyme, although not specific to rejection, is a good index of the degree of tubular damage.


2010 ◽  
Vol 23 (8) ◽  
pp. 993-999 ◽  
Author(s):  
Nihar Ranjan Sahoo ◽  
Pushpendra Kumar ◽  
Bharat Bhushan ◽  
T. K. Bhattacharya ◽  
Arjava Sharma ◽  
...  

Author(s):  
L.A. Tukhvatullina ◽  
◽  
R.G. Karimova ◽  
◽  

The article presents data on the dynamics of bactericidal activity of blood serum against St. aureus and E. coli, and the lysozyme activity of calf blood serum against Micrococcus lisodeicticus, as well as nitrate and nitrite anions when immunomodulators are administered. It has been established that administration of «Fosprenil» increases bactericidal and lysozyme activity of blood serum, whereas, Imunophane increases nonspecific resistance without affecting lysozyme activity. Nitric oxide (II) has been shown to be directly involved in the mechanism of non-specific immunity. At the same time, the stimulation of serum lysozyme activity requires nitric oxide (II) formation in high concentrations (above 50 µmol/l).


2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Alexandre Beaudry ◽  
Marlène Fortier ◽  
Stéphane Masson ◽  
Michel Auffret ◽  
Pauline Brousseau ◽  
...  

The blue mussel is a filter-feeding bivalve commonly used in ecotoxicological monitoring as a sentinel species. Due to climate change and the increase of temperature expected in marine environment, it is important to anticipate potential impacts on this species. The aim of this study was to investigate the immunocompetence of blue mussels acclimated to different temperatures and on the effects of increasing temperatures (5, 10 and 20°C). Different indices and gonad maturation stages were also determined throughout the experiments. Cell viability, phagocytosis, serum lysozyme activity and cyclooxygenase (COX) activity were evaluated as immune parameters. The cellular immunity was also evaluated after hemocytes exposure to various cadmium concentrations <em>in vitro</em>. The results obtained demonstrate modulation of hemocyte viability and the ability of these cells to phagocytize in absence of contaminants. After the exposure to cadmium, hemocytes showed greater viability at 5°C while maintaining a higher phagocytic competence. In addition, the lysozyme activity stayed stable at all tested temperatures, contrary to that of COX, which increased when the mussels were maintained at 20°C. The evaluation of indices demonstrated no reduction of general conditions during all the experiment despite the increase of temperature and the reduction of the digestive gland weight. Moreover, the lack of food does not affect gonad maturation and the spawning process.


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