Segment-by-segment histological analysis of the cervical division of the spinal cord and of the roots of the spinal nerves and ganglia in severe craniocerebral trauma

1990 ◽  
Vol 20 (3) ◽  
pp. 218-224
Author(s):  
K. G. Tayushev
NeuroImage ◽  
2019 ◽  
Vol 201 ◽  
pp. 116026 ◽  
Author(s):  
Kurt G. Schilling ◽  
Samantha By ◽  
Haley R. Feiler ◽  
Bailey A. Box ◽  
Kristin P. O’Grady ◽  
...  

2018 ◽  
Vol 128 (6) ◽  
pp. 1839-1849 ◽  
Author(s):  
Masafumi Hiramatsu ◽  
Kenji Sugiu ◽  
Tomoya Ishiguro ◽  
Hiro Kiyosue ◽  
Kenichi Sato ◽  
...  

OBJECTIVEThe aim of this retrospective multicenter cohort study was to assess the details of the angioarchitecture of arteriovenous fistulas (AVFs) at the craniocervical junction (CCJ) and to determine the associations between the angiographic characteristics and the clinical presentations and outcomes.METHODSThe authors analyzed angiographic and clinical data for patients with CCJ AVFs from 20 participating centers that are members of the Japanese Society for Neuroendovascular Therapy (JSNET). Angiographic findings (feeding artery, location of AV shunt, draining vein) and patient data (age, sex, presentation, treatment modality, outcome) were tabulated and stratified based on the angiographic types of the lesions, as diagnosed by a member of the CCJ AVF study group, which consisted of a panel of 6 neurointerventionalists and 1 spine neurosurgeon.RESULTSThe study included 54 patients (median age 65 years, interquartile range 61–75 years) with a total of 59 lesions. Five angiographic types were found among the 59 lesions: Type 1, dural AVF (22 [37%] of 59); Type 2, radicular AVF (17 [29%] of 59); Type 3, epidural AVF (EDAVF) with pial feeders (8 [14%] of 59); Type 4, EDAVF (6 [10%] of 59); and Type 5, perimedullary AVF (6 [10%] of 59). In almost all lesions (98%), AV shunts were fed by radiculomeningeal arteries from the vertebral artery that drained into intradural or epidural veins through AV shunts on the dura mater, on the spinal nerves, in the epidural space, or on the spinal cord. In more than half of the lesions (63%), the AV shunts were also fed by a spinal pial artery from the anterior spinal artery (ASA) and/or the lateral spinal artery. The data also showed that the angiographic characteristics associated with hemorrhagic presentations—the most common presentation of the lesions (73%)—were the inclusion of the ASA as a feeder, the presence of aneurysmal dilatation on the feeder, and CCJ AVF Type 2 (radicular AVF). Treatment outcomes differed among the angiographic types of the lesions.CONCLUSIONSCraniocervical junction AVFs commonly present with hemorrhage and are frequently fed by both radiculomeningeal and spinal pial arteries. The AV shunt develops along the C-1 or C-2 nerve roots and can be located on the spinal cord, on the spinal nerves, and/or on the inner or outer surface of the dura mater.


2017 ◽  
Vol 4 (3) ◽  
pp. 142-145
Author(s):  
O.E. Dukhovskyy

О. Dukhovskyy The study involved a comprehensive survey of 137 families (mother and father) of children with severe somatic disease aimed at the development and evaluation of the system of medical and psychological support of families with a somatically challenged child. The main group comprised 97 families participating in the program of medical and psychological support, and the control group included 40 families who did not receive psychological support. According to our findings, a serious disease of the child became a psychotraumatic situation for all the parents, resulting in the development of anxiety-depressive reactions and conditions. Psychodiagnostic examination showed that the parents had mild, moderate depressive and anxious episodes on the Hamilton Rating Scale; high levels of situational and personal anxiety according to the C.D. Spielberger Inventory, a high level of neuropsychic stress on T.A. Nemchin Scale. The couples under investigation noted tensions in family relationships, family conflicts, related to the treatment of the child and escalation of pre-existing interpersonal and marital problems that led to distancing and a decrease in internal family resource. Based on these data, we have developed a system of medical and psychological support of the families with somatically challenged child, which consisted of four consecutive phases and included the use of individual cognitive-behavioral therapy (Beck AT, 2006), family therapy (Eidemiller E. G., 2003), rational therapy (classic Dubois P., 1912) and psychological educational programs. Case monitoring in the main group following the employment of the proposed system of medical and psychological support showed a stable positive pattern of psychological state with a statistically significant total reduction of anxiety-depressive states and the harmonization of the marital relationship.Key words: Medical and psychological support, anxiety, depression, family interactions, infants with severe craniocerebral trauma. СУЧАСНІ ПІДХОДИ ДО МЕДИКО-ПСИХОЛОГІЧНОГО СУПРОВОДУ СІМ’Ї ДИТИНИ ПЕРШОГО РОКУ ЖИТТЯ З ВАЖКОЮ ЧЕРЕПНО-МОЗКОВОЮ ТРАВМОЮ.Духовський О.Є.У ході роботи з метою розробки та апробації системи медико-психологічного супроводу сім’ї дитини першого року життя з важкою черепно-мозковою травмою проведено комплексне обстеження 137 родини (мати та батько) дітей першого року життя які отримали важку черепно-мозкову травму. Основну групу склали 97 родин, які прийняли участь у програмі медико-психологічного супроводу, контрольну групу 40 родин, які не отримували психологічну підтримку. Як показали результати дослідження черепно-мозкова травма дитини стала психотравмуючою ситуацією для усіх батьків, яка приводила до розвитку тривожно-депресивних реакцій та станів. За даними психодіагностичного обстеження у батьків відмічалися легкій помірний депресивний та тривожний епізоди за шкалою Гамільтона; високі рівні ситуативної й особистісної тривожності за методикою Ч.Д. Спілбергера, високій рівень виразності нервово-психічної напруги по шкалі Т.А. Немчина. Обстежені родини відзначали наявність напруженості в сімейних відносинах, сімейні конфлікти, як пов’язані з лікуванням дитини, так і ескалації існуючих раніше міжособистісних та подружніх проблем, що призводило до дистанціювання та зниження внутрішньосімейного ресурсу. Базуючись на отриманих даних нами розроблена система медико-психологічного супроводу сімʼї дитини першого року життя з важкою черепно-мозковою травмою, яка складалася із чотирьох послідовних етапів та включла використання індивідуальної когнітивно-поведінкової терапії (Бек A. T., 2006), сімейної терапії (Ейдміллер Е. Г., 2003), раціональної психотерапії (класичний варіант Дюбуа П., 1912) та псих освітніх програм. Як показали результати динамічного спостереження, на фоні застосування запропонованої системи медико-психологічного супроводу в основній групі відзначена стійка позитивна динаміка психологічного стану з повною редукцією тривожно-депресивних та гармонізацією подружніх відносин.Ключові слова: Медико-психологічний супровід, тривога, депресія, родинна взаємодія, дитина з важкою черепно-мозковою травмою. СОВРЕМЕННЫЕ ПОДХОДЫ К МЕДИКО-ПСИХОЛОГИЧЕСКОМУ СОПРОВОЖДЕНИЮ СЕМЬИ РЕБЕНКА ПЕРВОГО ГОДА ЖИЗНИ С ТЯЖЕЛОЙ ЧЕРЕПНО-МОЗГОВОЙ ТРАВМОЙ.Духовской А.Э.В ходе работы с целью разработки и апробации системы медико-психологического сопровождения семьи ребенка первого года жизни с тяжелой черепно-мозговой травмой проведено комплексное обследование 137 семей (мать и отец) детей первого года жизни получивших тяжелую черепно-мозговую травму. Основную группу составили 97 семей, принявших участие в программе медико-психологического сопровождения, контрольную группу 40 семей, не получавшие психологическую поддержку. Как показали результаты исследования, черепно-мозговая травма ребенка стала психотравмирующей ситуацией для всех родителей, которая приводила к развитию тревожно-депрессивных реакций и состояний. По данным психодиагностического обследования у родителей отмечались легкой умеренный депрессивный и тревожный эпизоды по шкале Гамильтона; высокие уровни ситуативной и личностной тревожности по методике Ч.Д. Спилбергера, высокий уровень выраженности нервно-психического напряжения по шкале Т.А. Немчина. Обследованные супруги отмечали наличие напряженности в семейных отношениях, семейные конфликты, как связанные с лечением ребенка, так и эскалацией существующих ранее межличностных и супружеских проблем, чт приводило к дистанцированию и снижению внутрисемейного ресурса. Основываясь на полученных данных нами разработана система медико-психологического сопровождения семьи ребенка первого года жизни с тяжелой черепно-мозговой травмой, которая состояла из четырех последовательных этапов и включала использование индивидуальной когнитивно-поведенческой терапии (Бек AT, 2006), семейной терапии (Ейдмиллер Е. Г., 2003), рациональной психотерапии (классический вариант Дюбуа П., 1912) и психобразовательных программ. Как показали результаты динамического наблюдения, на фоне применения предложенной системы медико-психологического сопровождения в основной группе отмечена устойчивая положительная динамика психологического состояния с полной редукцией тревожно-депрессивных состояний и гармонизацией супружеских отношений.Ключевые слова: Медико-психологическое сопровождение, тревога, депрессия, семейное взаимодействие, ребенок с тяжелой черепно-мозговой травмой.


1997 ◽  
Vol 2 (5) ◽  
pp. E2
Author(s):  
Neil A. Martin ◽  
Ravish V. Patwardhan ◽  
Michael J. Alexander ◽  
Cynthia Zane Africk ◽  
Jae Hong Lee ◽  
...  

The extent and timing of posttraumatic cerebral hemodynamic disturbances have significant implications for the monitoring and treatment of patients with head injury. This prospective study of cerebral blood flow (CBF) (measured using 133Xe clearance) and transcranial Doppler (TCD) measurements in 125 patients with severe head trauma has defined three distinct hemodynamic phases during the first 2 weeks after injury. The phases are further characterized by measurements of cerebral arteriovenous oxygen difference (AVDO2) and cerebral metabolic rate of oxygen (CMRO2). Phase I (hypoperfusion phase) occurs on the day of injury (Day 0) and is defined by a low CBF15 calculated from cerebral clearance curves integrated to 15 minutes (mean CBF15 32.3 ± 2 ml/100 g/minute), normal middle cerebral artery (MCA) velocity (mean VMCA 56.7 ± 2.9 cm/second), normal hemispheric index (mean HI 1.67 ± 0.11), and normal AVDO2 (mean AVDO2 5.4 ± 0.5 vol%). The CMRO2 is approximately 50% of normal (mean CMRO2 1.77 ± 0.18 ml/100 g/minute) during this phase and remains depressed during the second and third phases. In Phase II (hyperemia phase, Days 1-3), CBF increases (46.8 ± 3 ml/100 g/minute), AVDO2 falls (3.8 ± 0.1 vol%), VMCA velocity rises (86 ± 3.7 cm/second), and the HI remains less than 3 (2.41 ± 0.1). In Phase III (vasospasm phase, Days 4-15), there is a fall in CBF (35.7 ± 3.8 ml/100 g/minute), a further increase in VMCA (96.7 ± 6.3 cm/second), and a pronounced rise in the HI (2.87 ± 0.22). This is the first study in which CBF, metabolic, and TCD measurements are combined to define the characteristics and time courses of, and to suggest etiological factors for, the distinct cerebral hemodynamic phases that occur after severe craniocerebral trauma. This research is consistent with and builds on the findings of previous investigations and may provide a useful temporal framework for the organization of existing knowledge regarding posttraumatic cerebrovascular and metabolic pathophysiology.


1955 ◽  
Vol 32 (1) ◽  
pp. 4-21
Author(s):  
D. R. NEWTH ◽  
D. M. ROSS

1. Myxine glutinosa responds to illumination by active locomotory movements. 2. The response to light occurs some time after the onset of illumination. This time can be resolved, after the method of Hecht, into a sensitization period and a latent period. 3. Analysis of the relation of sensitization period and latent period to intensity of illumination and other factors shows that photoreception in Myxine is essentially similar to that of a number of other animals, including the ammocoete, but suggests that the secondary reactions initiated by the production of photolytes during sensitization occur during both sensitization and latent periods and not during the latent period alone. 4. The photoreceptors of Myxine are located in the skin and are present only, or mostly, at the anterior end of the head and in the region of the cloaca. Nervous impulses travel from the posterior photoreceptors through spinal nerves to the spinal cord.


Author(s):  
Anna Clebone

Myelomeningocele, also known as spina bifida aperta (often shortened to the nonspecific name “spina bifida”) is a congenital disorder of the spine. In infants with a myelomeningocele, the neural tube has not closed, and the vertebral arches have not fused during development, leading to spinal cord and meningeal herniation through the skin. Because of the high potential for injury and infection of the exposed spinal cord, which could lead to lifetime disability, these lesions are typically repaired within 24 to 48 hours after birth. A myelomeningocele occurs before day 28 of human fetal development and is an abnormality in which the posterior neural tube closes incompletely. The outcome is a vertebral column deformity, through which the meningeal-lined sac herniates. After the bony defect is created, the hypothesized mechanism of meningeal herniation is that the pulsations of cerebrospinal fluid act progressively to balloon out the spinal cord. If the sac is filled with spinal nerves or the spinal cord, it is known as a myelomeningocele; if the sac is empty, it is called a meningocele.


2018 ◽  
pp. 669-678
Author(s):  
Edward Jack Ebani ◽  
Kathryn Dean ◽  
Apostolos John Tsiouris

This chapter on interventional-related spine anatomy provides a concise overview of normal spinal anatomy, as well as commonly encountered pathologic conditions, with a particular emphasis on the relevant imaging findings. The introduction outlines potential sources of back pain and their presenting symptomatology. The chapter reviews the main imaging modalities used to evaluate the spine and discusses their specific advantages and disadvantages. The anatomy of the muscles of the vertebral column, the vertebral column itself, and common variations), intervertebral ligaments and discs, vertebral joints, meninges and spinal cord, spinal nerves, and vasculature of the spinal column and spinal cord are reviewed. The discussion includes multiple radiographic, computed tomography (CT), magnetic resonance imaging (MRI), and angiographic images, as well as illustrations to supplement the text.


2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Li-Yun Jia ◽  
An-Hui Yao ◽  
Fang Kuang ◽  
Yu-Kai Zhang ◽  
Xue-Feng Shen ◽  
...  

Shu-Xue-Tong (SXT) is a traditional Chinese drug widely used to ameliorate stagnation of blood flow, such as brain or myocardial infarction. Whether SXT may have therapeutic value for spinal cord injury (SCI), during which ischemia plays an important role in its pathology, remains to be elucidated. We hypothesized that SXT may promote SCI healing by improving spinal cord blood flow (SCBF), and a study was thus designed to explore this possibility. Twenty-five male Sprague-Dawley rats were used. SCI was induced by compression, and SXT was administrated 24 h postinjury for 14 successive days. The effects of SXT were assessed by means of laser-Doppler flowmetry, motor functional analysis (open-field walking and footprint analysis), and histological analysis (hematoxylin-eosin and thionin staining and NeuN immunohistochemistry). SXT significantly promoted SCBF of the contused spinal cord and enhanced the recovery of motor function. Histological analysis indicated that the lesion size was reduced, the pathological changes were ameliorated, and more neurons were preserved. Based on these results we conclude that SXT can effectively improve SCI.


Author(s):  
Steve Casha ◽  
Philippe Mercier

The spinal cord and peripheral nerves carry motor and autonomic efferents, as well as sensory afferents connecting the cerebrum with the body. Efferent and afferent fibres form predictable tracts within the spinal cord, forming spinal nerves as they exit the spinal canal. Peripheral nerves are often formed from complicated plexuses of spinal nerves in the cervical, lumbar, and sacral spine. Dermatomes are formed from spinal nerves that innervate specific areas of skin, while myotomes innervate a specific set of muscles. The detailed anatomy of these structures are discussed. Knowledge of the anatomy of these structures is relevant to many clinical situations encountered in the intensive care unit especially with caring for neurological, neurosurgical, orthopaedic, and trauma patients.


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