Biological effects of a calcium supplementation in post menopausal women: effects of vitamin d status and dietary calcium

1996 ◽  
Vol 6 (S1) ◽  
pp. 270-270
Author(s):  
P. Fardellone ◽  
M. Brazier ◽  
JP. Berrou ◽  
G. Badot ◽  
J. Guéris ◽  
...  
Bone ◽  
2010 ◽  
Vol 46 (3) ◽  
pp. 759-767 ◽  
Author(s):  
Marlena C. Kruger ◽  
Linda M. Schollum ◽  
Barbara Kuhn-Sherlock ◽  
Andon Hestiantoro ◽  
Paulus Wijanto ◽  
...  

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 268-268
Author(s):  
Mariah Jackson ◽  
Ruiqian Wu ◽  
Lynette Smith ◽  
Joan Lappe ◽  
Corrine Hanson

Abstract Objectives Determine the extent to which diets with higher fiber intakes (g) at baseline are independently associated with cancer development by final study visit in a cohort of rural post-menopausal women. Methods This study was a secondary analysis of participants in a four-year randomized controlled trial evaluating the effect of vitamin D and calcium supplementation (2000 IU/d vitamin D3 and 1500 mg/d calcium) on cancer development in rural post-menopausal women in Nebraska (June 2009-August 2015). Diets, including fiber intake (total, soluble, fruit-vegetable, grain and bean fiber), were evaluated via a 2005 Block Food Frequency Questionnaire at baseline. T-tests were used to evaluate the difference in dietary fiber intakes between all-type cancer and non-cancer groups. Logistic regression models, controlling for pertinent covariates, were used to determine if dietary fiber intake at baseline is associated with the cancer development. Dietary fiber variables were log-transformed and stratified by treatment group. Results There were 1977 participants available for analysis. Median total fiber intake was 14.35 g or 65% of the Dietary Reference Intake. There was no significant difference between dietary fiber intakes at baseline between the cancer group and non-cancer group. For people on vitamin D and calcium supplementation, higher dietary soluble fiber and fruit-vegetable fiber intakes at baseline were protective against cancer development [Soluble OR: 0.50; 95% CI (0.26, 0.96); Fruit-vegetable OR: 0.56; 95% CI (0.33, 0.94)]. In participants without vitamin D and calcium supplementation, the odds of having higher bean fiber intake was 1.62 times higher in those with cancer [OR: 1.62 (95% CI (1.07, 2.47)]. Total fiber and grain fiber intakes were not significantly associated with cancer development. Conclusions While low fiber intake is prevalent among rural post-menopausal women, those with higher intakes of soluble and fruit-vegetable fiber may be more protected against development of all-type cancer when supplemented with calcium and vitamin D. Further analysis should examine the relationship between supplementation and bean fiber intake on the development of cancer. Funding Sources The original study was funded by the National Cancer Institute and Creighton University internal funding. No additional funding was used for the secondary analysis.


Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 713 ◽  
Author(s):  
Chad M. Kerksick ◽  
Michael D. Roberts ◽  
Bill I. Campbell ◽  
Melyn M. Galbreath ◽  
Lemuel W. Taylor ◽  
...  

Vitamin D and calcium supplementation have been posited to improve body composition and different formulations of calcium may impact bioavailability. However, data are lacking regarding the combinatorial effects of exercise, diet, and calcium and/or vitamin D supplementation on body composition changes in post-menopausal women. Herein, 128 post-menopausal women (51.3 ± 4.5 years, 36.4 ± 5.7 kg/m2, 46.2 ± 4.5% fat) were assigned to diet and supplement groups while participating in a supervised circuit-style resistance-training program (3 d/week) over a 14-week period. Diet groups included: (1) normal diet (CTL), (2) a low-calorie, higher protein diet (LCHP; 1600 kcal/day, 15% carbohydrates, 55% protein, 30% fat), and (3) a low-calorie, higher carbohydrate diet (LCHC; 1600 kcal/day, 55% carbohydrates, 15% protein, 30% fat). Supplement groups consisted of: (1) maltodextrin (PLA), (2) 800 mg/day of calcium carbonate (Ca), and (3) 800 mg/day of calcium citrate and malate and 400 IU/day of vitamin D (Ca+D). Fasting blood samples, body composition, resting energy expenditure, aerobic capacity, muscular strength and endurance measures were assessed. Data were analyzed by mixed factorial ANOVA with repeated measures and presented as mean change from baseline [95% CI]. Exercise training promoted significant improvements in strength, peak aerobic capacity, and blood lipids. Dieting resulted in greater losses of body mass (CTL −0.4 ± 2.4; LCHC −5.1 ± 4.2; LCHP −3.8 ± 4.2 kg) and fat mass (CTL −1.4 ± 1.8; LCHC −3.7 ± 3.7; LCHP −3.4 ± 3.4 kg). When compared to LCHC-PLA, the LCHC + Ca combination led to greater losses in body mass (PLA −4.1 [−6.1, −2.1], Ca −6.4 [−8.1, −4.7], Ca+D −4.4 [−6.4, −2.5] kg). In comparison to LCHC-Ca, the LCHC-Ca+D led to an improved maintenance of fat-free mass (PLA −0.3 [−1.4, 0.7], Ca −1.4 [−2.3, −0.5], Ca+D 0.4 [−0.6, 1.5] kg) and a greater loss of body fat (PLA −2.3 [−3.4, −1.1], Ca −1.3 [−2.3, −0.3], Ca+D −3.6 [−4.8, −2.5]%). Alternatively, no significant differences in weight loss or body composition resulted when adding Ca or Ca+D to the LCHP regimen in comparison to when PLA was added to the LCHP diet. When combined with an energy-restricted, higher carbohydrate diet, adding 800 mg of Ca carbonate stimulated greater body mass loss compared to when a PLA was added. Alternatively, adding Ca+D to the LCHC diet promoted greater% fat changes and attenuation of fat-free mass loss. Our results expand upon current literature regarding the impact of calcium supplementation with dieting and regular exercise. This data highlights that different forms of calcium in combination with an energy restricted, higher carbohydrate diet may trigger changes in body mass or body composition while no impact of calcium supplementation was observed when participants followed an energy restricted, higher protein diet.


1996 ◽  
Vol 6 (S1) ◽  
pp. 270-270
Author(s):  
S. Kamel ◽  
M. Brazier ◽  
P. Fardellone ◽  
Y. Rigault ◽  
JP Berrou ◽  
...  

2016 ◽  
Vol 2 (4) ◽  
pp. 1-17
Author(s):  
J. H. Elhissi ◽  
M. M. Elghaffari ◽  
M. H. Taleb ◽  
A. I. Ahmed ◽  
A. A. Najim

2013 ◽  
Vol 17 (9) ◽  
pp. 618 ◽  
Author(s):  
Sameer Aggarwal ◽  
Nityanand

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