In vivo changes in antioxidant systems and protective role of melatonin and a combination of vitamin C and vitamin E on oxidative damage in erythrocytes induced by chlorpyrifos-ethyl in rats

2001 ◽  
Vol 75 (2) ◽  
pp. 88-96 ◽  
Author(s):  
Fatih Gultekin ◽  
Namik Delibas ◽  
Sulhattin Yasar ◽  
Ibrahim Kilinc
Keyword(s):  
Vitamin E ◽  
Vitamin C ◽  
Oxidative Damage ◽  
Protective Role ◽  
Antioxidant Systems ◽  
Chlorpyrifos Ethyl

Protective role of melatonin and a combination of vitamin C and vitamin E on lung toxicity induced by chlorpyrifos-ethyl in rats

2002 ◽  
Vol 54 (2) ◽  
pp. 97-108 ◽  
Author(s):  
Erdal Karaoz ◽  
Fatih Gultekin ◽  
Mehmet Akdogan ◽  
Meral Oncu ◽  
Alpaslan Gokcimen
Keyword(s):  
Vitamin E ◽  
Vitamin C ◽  
Protective Role ◽  
Lung Toxicity ◽  
Chlorpyrifos Ethyl

Studies on the protective role of vitamin C and E against polychlorinated biphenyl (Aroclor 1254)—induced oxidative damage in Leydig cells

2005 ◽  
Vol 39 (11) ◽  
pp. 1259-1272 ◽  
Author(s):  
Palaniappan Murugesan ◽  
Thirupathi Muthusamy ◽  
Karundevi Balasubramanian ◽  
Jagadeesan Arunakaran
Keyword(s):  
Vitamin C ◽  
Oxidative Damage ◽  
Leydig Cells ◽  
Polychlorinated Biphenyl ◽  
Protective Role ◽  
Aroclor 1254

scholarly journals Protective Role of Sphingomyelin in Eye Lens Cell Membrane Model against Oxidative Stress

Biomolecules ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 276
Author(s):  
Mehdi Ravandeh ◽  
Giulia Coliva ◽  
Heike Kahlert ◽  
Amir Azinfar ◽  
Christiane A. Helm ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Oxidative Damage ◽  
Plasma Treatment ◽  
High Resolution Mass Spectrometry ◽  
Protective Role ◽  
Oxidation Products ◽  
Eye Lens ◽  
Antioxidant Systems ◽  
Lens Cell

In the eye lens cell membrane, the lipid composition changes during the aging process: the proportion of sphingomyelins (SM) increases, that of phosphatidylcholines decreases. To investigate the protective role of the SMs in the lens cell membrane against oxidative damage, analytical techniques such as electrochemistry, high-resolution mass spectrometry (HR-MS), and atomic force microscopy (AFM) were applied. Supported lipid bilayers (SLB) were prepared to mimic the lens cell membrane with different fractions of PLPC/SM (PLPC: 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine). The SLBs were treated with cold physical plasma. A protective effect of 30% and 44% in the presence of 25%, and 75% SM in the bilayer was observed, respectively. PLPC and SM oxidation products were determined via HR-MS for SLBs after plasma treatment. The yield of fragments gradually decreased as the SM ratio increased. Topographic images obtained by AFM of PLPC-bilayers showed SLB degradation and pore formation after plasma treatment, no degradation was observed in PLPC/SM bilayers. The results of all techniques confirm the protective role of SM in the membrane against oxidative damage and support the idea that the SM content in lens cell membrane is increased during aging in the absence of effective antioxidant systems to protect the eye from oxidative damage and to prolong lens transparency.

scholarly journals Protective role of maize purple plant pigment against oxidative stress in fluorosis rat brain

2020 ◽  
Vol 11 (1) ◽  
pp. 89-95
Author(s):  
Boyan Li ◽  
Keyana Nozzari Varkani ◽  
Lu Sun ◽  
Bo Zhou ◽  
Xiaohong Wang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Oxidative Damage ◽  
Rat Brain ◽  
Neuronal Apoptosis ◽  
Protective Role ◽  
Fluoride Toxicity ◽  
Plant Pigment

AbstractIn fluorosis-endemic areas, exposure to high levels of fluoride causes neurotoxicity such as lowered intelligence and cognitive impairment. Oxidative damage is critical to pathophysiologic processes of fluoride intoxication, and neurotoxicity of fluoride may be associated with oxidative stress. In previous studies, maize purple plant pigment (MPPP), which was rich in anthocyanins, showed a strong scavenging activity in vitro and in vivo. The present study aimed to determine whether treatment with MPPP can alleviate fluoride-induced oxidative damage in rat brain. After 3 months of experiment, brain tissues were assayed for oxidative stress variables, histological and Western blotting examinations. Our results showed that MPPP reduced the elevated malondialdehyde levels, increased superoxide dismutase activity, and further attenuated histopathological alterations and mitigated neuronal apoptosis. Importantly, MPPP also reversed changes in Bax and Bcl-2. Therefore, it was speculated that MPPP protects brain tissue from fluoride toxicity through its antioxidant capacity.

Effect of Aging on Cornea of Male Albino Rat and the Possible Protective Role of Vitamin C

2020 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Hanan Yassa ◽  
Gaber Hussein ◽  
Shimaa Kotb ◽  
azza embaby
Keyword(s):  
Vitamin C ◽  
Protective Role ◽  
Albino Rat

scholarly journals cROStalk for Life: Uncovering ROS Signaling in Plants and Animal Systems, from Gametogenesis to Early Embryonic Development

Genes ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 525
Author(s):  
Valentina Lodde ◽  
Piero Morandini ◽  
Alex Costa ◽  
Irene Murgia ◽  
Ignacio Ezquer
Keyword(s):  
Signal Transduction ◽  
Signaling Pathways ◽  
Analytical Techniques ◽  
Antioxidant Systems ◽  
Developmental Studies ◽  
Science Field ◽  
Ros Signaling ◽  
Reproductive Processes

This review explores the role of reactive oxygen species (ROS)/Ca2+ in communication within reproductive structures in plants and animals. Many concepts have been described during the last years regarding how biosynthesis, generation products, antioxidant systems, and signal transduction involve ROS signaling, as well as its possible link with developmental processes and response to biotic and abiotic stresses. In this review, we first addressed classic key concepts in ROS and Ca2+ signaling in plants, both at the subcellular, cellular, and organ level. In the plant science field, during the last decades, new techniques have facilitated the in vivo monitoring of ROS signaling cascades. We will describe these powerful techniques in plants and compare them to those existing in animals. Development of new analytical techniques will facilitate the understanding of ROS signaling and their signal transduction pathways in plants and mammals. Many among those signaling pathways already have been studied in animals; therefore, a specific effort should be made to integrate this knowledge into plant biology. We here discuss examples of how changes in the ROS and Ca2+ signaling pathways can affect differentiation processes in plants, focusing specifically on reproductive processes where the ROS and Ca2+ signaling pathways influence the gametophyte functioning, sexual reproduction, and embryo formation in plants and animals. The study field regarding the role of ROS and Ca2+ in signal transduction is evolving continuously, which is why we reviewed the recent literature and propose here the potential targets affecting ROS in reproductive processes. We discuss the opportunities to integrate comparative developmental studies and experimental approaches into studies on the role of ROS/ Ca2+ in both plant and animal developmental biology studies, to further elucidate these crucial signaling pathways.

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