A new method of high-speed cellular protein separation and insight into subcellular compartmentalization of proteins

2011 ◽  
Vol 400 (3) ◽  
pp. 767-775 ◽  
Author(s):  
Evelyn Png ◽  
WanWen Lan ◽  
Melisa Lazaroo ◽  
Silin Chen ◽  
Lei Zhou ◽  
...  
Keyword(s):  
Protein Separation ◽  
High Speed ◽  
Cellular Protein ◽  
New Method ◽  
Subcellular Compartmentalization ◽  
Insight Into

A new method used for high speed pseudo-random code generating

2014 ◽  
Author(s):  
Zhanfeng Zhao ◽  
Dong Zhang ◽  
Zhiquan Zhou
Keyword(s):  
High Speed ◽  
New Method ◽  
Random Code

scholarly journals A New Method to Verify the Measurement Speed and Accuracy of Frequency Modulated Interferometers

2021 ◽  
Vol 11 (13) ◽  
pp. 5787
Author(s):  
Toan-Thang Vu ◽  
Thanh-Tung Vu ◽  
Van-Doanh Tran ◽  
Thanh-Dong Nguyen ◽  
Ngoc-Tam Bui
Keyword(s):  
Phase Change ◽  
High Speed ◽  
Measurement Accuracy ◽  
Slow Motion ◽  
New Method ◽  
Virtual Displacement ◽  
Electro Optic ◽  
Lock In ◽  
Speed And Accuracy ◽  
Electro Optic Modulator

The measurement speed and measurement accuracy of a displacement measuring interferometer are key parameters. To verify these parameters, a fast and high-accuracy motion is required. However, the displacement induced by a mechanical actuator generates disadvantageous features, such as slow motion, hysteresis, distortion, and vibration. This paper proposes a new method for a nonmechanical high-speed motion using an electro-optic modulator (EOM). The method is based on the principle that all displacement measuring interferometers measure the phase change to calculate the displacement. This means that the EOM can be used to accurately generate phase change rather than a mechanical actuator. The proposed method is then validated by placing the EOM into an arm of a frequency modulation interferometer. By using two lock-in amplifiers, the phase change in an EOM and, hence, the corresponding virtual displacement could be measured by the interferometer. The measurement showed that the system could achieve a displacement at 20 kHz, a speed of 6.08 mm/s, and a displacement noise level < 100 pm//√Hz above 2 kHz. The proposed virtual displacement can be applied to determine both the measurement speed and accuracy of displacement measuring interferometers, such as homodyne interferometers, heterodyne interferometers, and frequency modulated interferometers.

Diplomacy Beyond History: Analytic-Violence, Producer-Centred Research, India

2021 ◽  
pp. 097492842098307
Author(s):  
Deep K. Datta-Ray
Keyword(s):  
New Method ◽  
The West ◽  
History Of ◽  
The Right ◽  
Nuclear Diplomacy ◽  
The Cost ◽  
Insight Into

The history of Indian diplomacy conceptualises diplomacy racially—as invented by the West—and restrictively—to offence. This is ‘analytic-violence’ and it explains the berating of Indians for mimicking diplomacy incorrectly or unthinkingly, and the deleting, dismissing, or denigrating, of diplomatic practices contradicting history’s conception. To relieve history from these offences, a new method is presented, ‘Producer-Centred Research’ (PCR). Initiating with abduction, an insight into a problem—in this case Indian diplomacy’s compromised historicisation—PCR solves it by converting history’s racist rationality into ‘rationalities’. The plurality renders rationality one of many, permitting PCR’s searching for rationalities not as a function of rationality but robust practices explicable in producer’s terms. Doing so is exegesis. It reveals India’s nuclear diplomacy as unique, for being organised by defence, not offence. Moreover, offence’s premise of security as exceeding opponent’s hostility renders it chimerical for such a security is, paradoxically, reliant on expanding arsenals. Additionally, doing so is a response to opponents. This fragments sovereignty and abdicates control for one is dependent on opponent’s choices. Defence, however, does not instigate opponents and so really delivers security by minimising arsenals since offence is eschewed. Doing so is not a response to opponents and so maintains sovereignty and retains control by denying others the right to offense. The cost of defence is courage, for instance, choosing to live in the shadow of nuclear annihilation. Exegesis discloses Balakot as a shift from defence to offence, so to relieve the Bharatiya Janata Party’s (BJP) leadership of having to be courageous. The intensity of the intention to discard courage is apparent in the price the BJP paid. This included equating India with Pakistan, permitting it to escalate the conflict, and so imperiling all humanity in a manner beyond history.

A New “Bounce-Normal” Boundary in DPD Calculations for the Reduction of Density Fluctuations

2008 ◽  
Author(s):  
Emadaldin Moeendarbary ◽  
K. Y. Lam ◽  
T. Y. Ng
Keyword(s):  
Shear Stress ◽  
Protein Separation ◽  
Dissipative Particle Dynamics ◽  
Computational Cost ◽  
Colloidal Suspensions ◽  
Density Fluctuations ◽  
Polymer Chains ◽  
New Method ◽  
Mems Devices ◽  
Macroscopic Properties

Dissipative Particle Dynamics (DPD) is a mesoscopic fluid modeling method, which facilitates the simulation of the statics and dynamics of complex fluid systems at physically interesting length and time scales. Currently, there are various applications of DPD, such as colloidal suspensions, multi-phase flow, rheology of polymer chains, DNA macromolecular suspension, etc., which employ this technique for their numerical simulation. The DPD technique is capable of modeling macroscopic properties of the bulk flow very well, but difficulties arise if the flows are confined through wall-bounded regions, or when different boundaries simultaneously exist in the simulation domain. These boundaries cause negative effects on the macroscopic temperature, density and velocity profiles, as well as the shear stress and pressure distributions. In particular, the interaction of DPD particles with solid boundaries causes large density fluctuations at the near wall regions. This density distortion leads to pronounced fluctuations in the pressure and shear stress, which are not actually present. To overcome these serious deficiencies, we introduce a new method in this work, which uses a combination of randomly distributed wall particles and a novel reflection adaptation at the wall. This new methodology is simple to implement and incurs no additional computational cost. More importantly, it does not cause any distortion in the macroscopic properties. This novel reflection adaptation is a novel version of the bounce back reflection, which we shall term the bounce-normal reflection. The most important characteristic of this method is that it reduces density fluctuations near the boundaries without affecting the velocity and temperature profiles. This new method is easily applicable to any wall-bounded problem with stationary boundaries and it has a very good consistency with macroscopic features. The eventual objective of this numerical development work is to investigate suspension flow through micro/nano channels of fluidic NEMS/MEMS devices, with applications to DNA and protein separation. These micro/nano channel devices, consisting of many entropic traps, are designed and fabricated for the separation of proteins and long DNA molecules.

scholarly journals Address of the President Sir Henry Dale, C.B.E., at the Anniversary Meeting, 1 December 1941

1942 ◽  
Vol 179 (978) ◽  
pp. 233-260 ◽  
Keyword(s):  
Technical College ◽  
High Speed ◽  
Large Scale ◽  
Electrical Engineering ◽  
The United States ◽  
The Past ◽  
Pure Mathematics ◽  
Symbolic Structure ◽  
The Church ◽  
Insight Into

This is the first occasion on which I have had the great honour of addressing the Royal Society on this anniversary of its foundation. According to custom, I begin with brief mention of those whom death has taken from our Fellowship during the past year, and whose memories we honour. Alfred Young (1873-1940), distinguished for his contributions to pure mathematics, was half brother to another of our Fellows, Sydney Young, a chemist of eminence. Alfred Young had an insight into the symbolic structure and manipulation of algebra, which gave him a special place among his mathematical contemporaries. After a successful career at Cambridge he entered the Church, and passed his later years in the country rectory of Birdbrook, Essex. His devotion to mathematics continued, however, throughout his life, and he published a steady stream of work in the branch of algebra which he had invented, and named ‘quantitative substitutional analysis’. He lived to see his methods adopted by Weyl in his quantum mechanics and spectroscopy. He was elected to our Fellowship in 1934. With the death of Miles Walker (1868-1941) the Society loses a pioneer in large-scale electrical engineering. Walker was a man of wide interests. He was trained first for the law, and even followed its practice for a period. Later he studied electrical engineering under Sylvanus Thompson at the Finsbury Technical College and became his assistant for several years. Thereafter, encouraged by Thompson, he entered St John’s College, Cambridge, with a scholarship, and graduated with 1st Class Honours in both the Natural Sciences and the Engineering Tripos. Having entered the service of the British Westinghouse Company, he was sent by them to the United States of America to study electrical engineering with the parent company in Pittsburgh. On his return to England he became their leading designer of high-speed electrical generators

Effective Stripper-Holding on High Speed Precision Blanking of Electronic Machine Parts

2005 ◽  
Vol 6-8 ◽  
pp. 805-808
Author(s):  
F. Sekine
Keyword(s):  
Mechanical Model ◽  
High Speed ◽  
Thin Sheet ◽  
Dimensional Accuracy ◽  
New Method ◽  
Important Process ◽  
Sheet Metals ◽  
Progressive Dies ◽  
Machine Parts

The blanking of thin sheet metals using progressive dies is an important process on production of precision electronic machine parts. As a model of IC leadframe, an I-shaped and an Lshaped models were blanked and influences of blanking conditions on dimensional accuracy of blanked lead were examined. Furthermore, a mechanical model is proposed to explain the affect of the blanking conditions on product accuracy. In these days, more fine leads are required as electronic machines become more precise and accurate. It must be treated that leads are firmly held for blanking leadframes accurately. In this paper, an effective method of stripper holding leads strongly are discussed and a new method using newly designed stripper is proposed. Consequently the effect of it on lead accuracy is proved.

The Mechanical Design of Large Turbogenerators

1987 ◽  
Vol 201 (2) ◽  
pp. 91-103
Author(s):  
B A Marlow
Keyword(s):  
High Speed ◽  
Mechanical Design ◽  
Rotating Machinery ◽  
Design Problems ◽  
Detail Design ◽  
Insight Into

Experience shows that the reliability of large turbogenerators depends substantially on the quality of detail design, particularly the quality of the mechanical design. In addition to the design problems common to all high-speed rotating machinery, the mechanical design of generators must take account of certain electrical requirements. This paper gives an insight into the detail mechanical design of large turbogenerators paying particular attention to the interaction of electrical requirements on the mechanical design.

A new method for human milk protein separation

Biochimie ◽  
1982 ◽  
Vol 64 (3) ◽  
pp. 231-235 ◽  
Author(s):  
Ghislaine Brignon ◽  
Bruno Ribadeau-Dumas
Keyword(s):  
Human Milk ◽  
Protein Separation ◽  
Milk Protein ◽  
New Method ◽  
Human Milk Protein

A New Method of Torque Compensation for High Speed Indexing Cam Mechanism

1999 ◽  
Vol 121 (2) ◽  
pp. 319-323 ◽  
Author(s):  
Teng Guilan ◽  
Fu Haibo ◽  
Zhou Weiyi
Keyword(s):  
Kinetic Energy ◽  
High Speed ◽  
Output Shaft ◽  
New Method ◽  
Linkage Mechanism ◽  
Energy Fluctuation ◽  
Positioning Accuracy ◽  
Input Shaft ◽  
Cam Mechanism

Severe vibration and poor positioning accuracy may occur in an indexing cam mechanism operating at a high speed. Torque fluctuation of the input shaft and the resulting fluctuation of kinetic energy of the mechanism may be the major cause of the vibration. In this paper a method is proposed to minimize the fluctuation by using a so-called “speed-varying flywheel” that produces an opposite kinetic energy fluctuation that can counteract the effect of the energy fluctuation. The flywheel is installed on the output shaft of an additional cam-linkage mechanism. The parameter of the cam-linkage mechanism is optimized. An example is given to demonstrate the effectiveness of this method.

Sign in / Sign up

Export Citation Format

Share Document