The effect of an osteolytic tumor on the three-dimensional trabecular bone morphology in an animal model

2001 ◽  
Vol 30 (2) ◽  
pp. 94-98 ◽  
Author(s):  
A. A. Kurth ◽  
R. Müller
1986 ◽  
Vol 4 (3) ◽  
pp. 304-317 ◽  
Author(s):  
D. P. Fyhrie ◽  
D. R. Carter

2007 ◽  
Vol 30 (6) ◽  
pp. 1082-1089 ◽  
Author(s):  
A. R. Froese ◽  
K. Ask ◽  
R. Labiris ◽  
T. Farncombe ◽  
D. Warburton ◽  
...  

2014 ◽  
Vol 695 ◽  
pp. 588-591
Author(s):  
Khairul Salleh Basaruddin ◽  
Ruslizam Daud

This study aims to investigate the influence of trabecular bone in human mandible bone on the mechanical response under implant load. Three dimensional voxel finite element (FE) model of mandible bone was reconstructed from micro-computed tomography (CT) images that were captured from bone specimen. Two FE models were developed where the first consists of cortical bone, trabecular bone and implants, and trabecular bone part was excluded in the second model. A static analysis was conducted on both models using commercial software Voxelcon. The results suggest that trabecular bone contributed to the strength of human mandible bone and to the effectiveness of load distribution under implant load.


2014 ◽  
Vol 22 ◽  
pp. S328
Author(s):  
B.D. Beynnon ◽  
C.E. Birch ◽  
K.S. Mensch ◽  
M.J. DeSarno ◽  
M. Gardner-Morse ◽  
...  

2021 ◽  
Author(s):  
Mohammad Kamal ◽  
Sara Al-Obaidly ◽  
Bernd Lethaus ◽  
Alexander K. Bartella

Abstract Background: Bone grafting is commonly used for reconstructing skeletal defects in the craniofacial region. Several bone augmentation models were developed to optimize bone regeneration in both vertical and horizontal dimesions. Aim: The aim of this study was to develop a surgical animal model for establishing a three-dimensional (3D) grafting environment in the animal's mandibular ramus for horizontal and vertical bone regeneration using osseous shell technique, as in human patients. Materials and methods: Initial osteological and imaging survey were performed on a postmortem skull of a New Zealand White (NZW) rabbit skull, Oryctolagus cuniculus, for feasibility assessment for performing the surgical procedure. 3D osseus defect was created in the mandibular ramus through a submandibular incision and the osseous shell plates were stabilized with osteosynthesis fixation screws and defect filled with particular bone grafting material. The in-vivo surgical procedures were conducted in four 8-week-old NZW rabbits utilising two osseous shell materials: xenogenic human cortical plates, and autogenous rabbit cortical plates, and the created 3D defects were filled using xenograft and allograft bone grafting materials. The healed defects were evaluated for bone regeneration after 12 weeks using histological and Cone Beam Computed Tomography (CBCT) imaging analysis. Results: Clinical analysis at 12 weeks after surgery revealed the stability of the 3D grafted bone augmentation defects using the osseous shell technique. Imaging and histological analyses confirmed the effectiveness of this model in assessing bone regeneration. Conclusion: The rabbit model is an efficient and reliable biological method for creating a seizable three-dimensional horizontal and vertical bone regeneration model in the mandibular ramus using osseous shell technique for testing various bone-substitute materials testing without compromising the health of the animal. The filled defects could be analyzed for osteogenesis, quantification of bone formation, and healing potential, using histomorphometric analysis, in addition to 3D morphologic evaluation using radiation imaging.


2019 ◽  
Vol 51 (Supplement) ◽  
pp. 755-756 ◽  
Author(s):  
Matthew C. Scott ◽  
Scott E. Fuller ◽  
James D. Watt ◽  
Michelle L. Osborn ◽  
Neil M. Johannsen ◽  
...  

1988 ◽  
Vol 17 (4) ◽  
pp. 169-173 ◽  
Author(s):  
L H Yahia ◽  
G Drouin ◽  
P Duval

Vertebral trabecular bone was tested by non-destructive uniaxial and triaxial loadings with the purpose of investigating the orthotropic properties of bone. A triaxial testing apparatus using hydrostatic pressure was developed and allowed to characterise the bony tissue in a three-dimensional stressed state. Thirty specimens, in the form of 10 mm cubes, were tested. The Young's moduli obtained in this study for the trabecular bone of human lumbar vertebrae are found to be in agreement with the values obtained by ultrasonic methods. Analyses of triaxial compressive tests provided, for the first time, the Poisson's ratios of vertebral trabecular bone. These values are found to satisfy thermodynamic restrictions established by Cowin and Van Buskirk (1986). Finally, no significant differences in the material properties were found for segment level (L3-L4).


PLoS ONE ◽  
2014 ◽  
Vol 9 (9) ◽  
pp. e107545 ◽  
Author(s):  
Jui-Ting Hsu ◽  
Ying-Ju Chen ◽  
Jung-Ting Ho ◽  
Heng-Li Huang ◽  
Shun-Ping Wang ◽  
...  

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