Immunostimulatory effect of quaternary degree and acetyl group of quaternized chitosan on macrophages RAW 264.7

2022 ◽  
Author(s):  
Xiaomin Li ◽  
Rong’e Xing ◽  
Chaojie Xu ◽  
Song Liu ◽  
Yukun Qin ◽  
...  
Keyword(s):  
Raw 264.7 ◽  
Immunostimulatory Effect ◽  
Quaternized Chitosan ◽  
Acetyl Group

The immunostimulatory effect of novel immunostimulator CH2b with a thiazolidin-4-one ring on the functions of LPS-activated RAW 264.7 macrophages in vitro

2013 ◽  
Vol 17 (3) ◽  
pp. 698-703 ◽  
Author(s):  
Chunxiao Li ◽  
Ming Meng ◽  
Dongzhi Chen ◽  
Zerui Wang ◽  
Hua Han ◽  
...  
Keyword(s):  
Raw 264.7 ◽  
Raw 264.7 Macrophages ◽  
Immunostimulatory Effect

scholarly journals Immunostimulatory Effect of Laminarin on RAW 264.7 Mouse Macrophages

Molecules ◽  
2012 ◽  
Vol 17 (5) ◽  
pp. 5404-5411 ◽  
Author(s):  
Ji Young Lee ◽  
Young-Jin Kim ◽  
Hyun Joo Kim ◽  
Yoon-Sang Kim ◽  
Wansu Park
Keyword(s):  
Raw 264.7 ◽  
Immunostimulatory Effect ◽  
Mouse Macrophages

scholarly journals The immunostimulatory effect of indole-6-carboxaldehyde isolated from Sargassum thunbergii (Mertens) Kuntze in RAW 264.7 macrophages

2020 ◽  
Vol 24 (4) ◽  
pp. 233-241
Author(s):  
Cheol Park ◽  
Hyun HwangBo ◽  
Hyesook Lee ◽  
Gi-Young Kim ◽  
Hee-Jae Cha ◽  
...  
Keyword(s):  
Raw 264.7 ◽  
Sargassum Thunbergii ◽  
Raw 264.7 Macrophages ◽  
Immunostimulatory Effect

scholarly journals The Bacterial Product Violacein Exerts an Immunostimulatory Effect Via TLR8

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Francisco A. Venegas ◽  
Gabriele Köllisch ◽  
Kerstin Mark ◽  
Wibke E. Diederich ◽  
Andreas Kaufmann ◽  
...  
Keyword(s):  
Mononuclear Cells ◽  
Immune Cell ◽  
Human Peripheral Blood ◽  
Biological Activities ◽  
Immune Therapy ◽  
Raw 264.7 Cells ◽  
Raw 264.7 ◽  
Peripheral Blood Mononuclear ◽  
Hek 293 ◽  
Immunostimulatory Effect

Abstract Violacein, an indole-derived, purple-colored natural pigment isolated from Chromobacterium violaceum has shown multiple biological activities. In this work, we studied the effect of violacein in different immune cell lines, namely THP-1, MonoMac 6, ANA-1, Raw 264.7 cells, as well as in human peripheral blood mononuclear cells (PBMCs). A stimulation of TNF-α production was observed in murine macrophages (ANA-1 and Raw 264.7), and in PBMCs, IL-6 and IL-1β secretion was detected. We obtained evidence of the molecular mechanism of activation by determining the mRNA expression pattern upon treatment with violacein in Raw 264.7 cells. Incubation with violacein caused activation of pathways related with an immune and inflammatory response. Our data utilizing TLR-transfected HEK-293 cells indicate that violacein activates the human TLR8 (hTLR8) receptor signaling pathway and not human TLR7 (hTLR7). Furthermore, we found that the immunostimulatory effect of violacein in PBMCs could be suppressed by the specific hTLR8 antagonist, CU-CPT9a. Finally, we studied the interaction of hTLR8 with violacein in silico and obtained evidence that violacein could bind to hTLR8 in a similar fashion to imidazoquinoline compounds. Therefore, our results indicate that violacein may have some potential in contributing to future immune therapy strategies.

Immunostimulatory effect by aqueous extract of Hizikia fusiforme in RAW 264.7 macrophage and whole spleen cells

2011 ◽  
Vol 16 (6) ◽  
pp. 1099-1105 ◽  
Author(s):  
Yeo Dae Yoon ◽  
Eun Sook Lee ◽  
Jong Pil Park ◽  
Mee Ree Kim ◽  
Jun Won Lee ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
Raw 264.7 ◽  
Spleen Cells ◽  
Immunostimulatory Effect ◽  
Raw 264.7 Macrophage ◽  
Hizikia Fusiforme

Effects of the extracts from Turkish medicinal plants on NF-κB activation on LPS-induced RAW 264.7 macrophages

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
I Atay ◽  
AZ İlter ◽  
D Telci ◽  
H Kırmızıbekmez ◽  
E Yeşilada
Keyword(s):  
Medicinal Plants ◽  
Raw 264.7 ◽  
Raw 264.7 Macrophages

5,7-Dihydroxyflavone analogues may regulate lipopolysaccharide-induced inflammatory responses by suppressing IκBα-linked Akt and ERK5 phosphorylation in RAW 264.7 macrophages

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
A Nishina ◽  
M Ukiya ◽  
M Fukatsu ◽  
M Koketsu ◽  
M Ninomiya ◽  
...  
Keyword(s):  
Inflammatory Responses ◽  
Raw 264.7 ◽  
Raw 264.7 Macrophages

Polyunsaturated fatty acids and phytoestrogens modulate osteoclastogenesis and bone resorption in raw 264.7 macrophages

2013 ◽  
Author(s):  
Natalie Shepherd ◽  
Jager Cassandre De ◽  
Abe Kasonga ◽  
Sumari Marais ◽  
Yuko Tousen ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Bone Resorption ◽  
Polyunsaturated Fatty Acids ◽  
Raw 264.7 ◽  
Raw 264.7 Macrophages

NEUTRALIZATION OF THE ANTICOAGULANT ACTIVITY OF HEPARIN BY CONJUGATES QUATERNIZED CHITOSAN WITH GALLIC ACID

2018 ◽  
Vol 2 (3) ◽  
pp. 7-12
Author(s):  
N.N. Drozd ◽  
◽  
A.P. Lun'kov ◽  
A.V. Il'ina ◽  
V.P. Varlamov ◽  
...  
Keyword(s):  
Gallic Acid ◽  
Anticoagulant Activity ◽  
Quaternized Chitosan
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