New strategies in diagnosis and treatment of thrombotic thrombocytopenic purpura: case report and review

1999 ◽  
Vol 158 (11) ◽  
pp. 883-887 ◽  
Author(s):  
J. Häberle ◽  
B. Kehrel ◽  
J. Ritter ◽  
H. Jürgens ◽  
B. Lämmle ◽  
...  
Keyword(s):  
Case Report ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Diagnosis And Treatment ◽  
Thrombocytopenic Purpura ◽  
New Strategies

scholarly journals Postoperative Thrombotic Thrombocytopenic Purpura after Total Hip Arthroplasty: A Case Report and Review of the Literature

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Nick N. Patel ◽  
Jason A. Shah ◽  
Christopher K. Sadlack
Keyword(s):  
Case Report ◽  
Mortality Rate ◽  
Total Hip Arthroplasty ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Hip Arthroplasty ◽  
Case Reports ◽  
Diagnosis And Treatment ◽  
Review Of The Literature ◽  
Thrombocytopenic Purpura ◽  
Total Hip

Thrombotic thrombocytopenic purpura (TTP) is an uncommon and potentially lethal microangiopathy that carries a >90% mortality rate if not treated urgently and appropriately. Postoperative TTP after orthopaedic procedures is particularly rare with only four case reports existing in the literature. We present the case of postoperative TTP in a 57-year-old female who underwent elective total hip arthroplasty. We believe this case adds to the limited literature surrounding the topic. While rare, TTP after orthopaedic procedures poses a real and potentially fatal condition if not managed appropriately. Therefore, it is essential for orthopaedic surgeons to be cognizant of postoperative TTP for timely diagnosis and treatment.

Effectiveness of bortezomib in the treatment of thrombotic thrombocytopenic purpura: Case report

2019 ◽  
Vol 152 (6) ◽  
pp. 244-245
Author(s):  
Eva Hernández Lorente ◽  
Rafael Lluch García ◽  
Emilio Monteagudo Santolaya
Keyword(s):  
Case Report ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Thrombocytopenic Purpura

scholarly journals An Early Unexpected Immune Thrombotic Thrombocytopenic Purpura Relapse Associated with SARS-CoV-2 Infection: A Case Report and Literature Review

2021 ◽  
pp. 1-5
Author(s):  
Maya Kornowski Cohen ◽  
Liron Sheena ◽  
Yair Shafir ◽  
Vered Yahalom ◽  
Anat Gafter-Gvili ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Case Report ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Lupus Erythematosus ◽  
Response To Therapy ◽  
Intravascular Hemolysis ◽  
Systemic Lupus ◽  
Thrombocytopenic Purpura ◽  
History Of ◽  
Triggering Factor

SARS-CoV-2 has been reported as a possible triggering factor for the development of several autoimmune diseases and inflammatory dysregulation. Here, we present a case report of a woman with a history of systemic lupus erythematosus and antiphospholipid syndrome, presenting with concurrent COVID-19 infection and immune thrombotic thrombocytopenic purpura (TTP). The patient was treated with plasma exchange, steroids, and caplacizumab with initial good response to therapy. The course of both TTP and COVID-19 disease was mild. However, after ADAMTS-13 activity was normalized, the patient experienced an early unexpected TTP relapse manifested by intravascular hemolysis with stable platelet counts requiring further treatment. Only 3 cases of COVID-19 associated TTP were reported in the literature thus far. We summarize the literature and suggest that COVID-19 could act as a trigger for TTP, with good outcomes if recognized and treated early.

scholarly journals Thrombotic thrombocytopenic purpura associated with dengue and chikungunya virus coinfection: case report during an epidemic period

2018 ◽  
Vol 60 (0) ◽  
Author(s):  
Maria Luiza Almeida Bastos ◽  
Ruth Maria Oliveira de Araújo ◽  
Deivide de Sousa Oliveira ◽  
Ana Nery Melo Cavalcante ◽  
Geraldo Bezerra da Silva Junior
Keyword(s):  
Case Report ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Chikungunya Virus ◽  
Thrombocytopenic Purpura ◽  
Epidemic Period
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