Studies on effect of Acalypha indica L. (Euphorbiaceae) leaf extracts on the malarial vector, Anopheles stephensi Liston (Diptera:Culicidae)

The herb Acalypha indica which belongs to Euphorbiaceae family has multiple medicinal properties which include anti-oxidant, anti-bacterial, anti-fungal, anti-inflammatory, antiulcer, anti-helmintic, anti-cancerous, anti-venom, and neuro-protective activity. The present study was designed to evaluate the phytochemical, antimicrobial and anti-oxidant activity of Acalypha indica leaves extracts in different solvent extractions like methanol, hexane, ethyl acetate and petroleum ether. Fresh leaves of the plant were collected and shade dried. Dried leaves were milled to obtain powder. Powder was subjected to soxhlet extraction using solvents and extracts were successively obtained. Phytochemical analysis was conducted following standard methods. Phytochemical analysis showed the presence of Alkaloids, Phenols, Saponins, Flavanoids and Amino acids. Leaf extract of methonal have shown the highest anti-oxidation capacity than hexane, ethyl acetate and petroleum ether. Anti-microbial activity has been performed on microbes like Bacillus sps, E.coli, Psuedomonas sps and Streptococcus sps. A highest value of zone of inhibition was found in methanol extract against E.coli. These results provide evidence that Acalypha indica leaf extract possesses vital phytochemicals, antimicrobial and antioxidant properties. Hence this plant can be studied further for drug analysis for finding potent medicines for diseases.

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Potential mode of action of a novel plumbagin as a mosquito repellent against the malarial vector Anopheles stephensi, (Culicidae: Diptera)

Pesticide Biochemistry and Physiology ◽

10.1016/j.pestbp.2016.04.001 ◽

2016 ◽

Vol 134 ◽

pp. 84-93 ◽

Cited By ~ 15

Author(s):

Venkatraman Pradeepa ◽

Sengottayan Senthil-Nathan ◽

Subbiah Sathish-Narayanan ◽

Selvaraj Selin-Rani ◽

Prabhakaran Vasantha-Srinivasan ◽

...

Keyword(s):

Mode Of Action ◽

Anopheles Stephensi ◽

Mosquito Repellent ◽

Potential Mode ◽

Malarial Vector

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Antimalarial efficacy of dynamic compound of plumbagin chemical constituent from Plumbago zeylanica Linn (Plumbaginaceae) against the malarial vector Anopheles stephensi Liston (Diptera: Culicidae)

Parasitology Research ◽

10.1007/s00436-014-4015-5 ◽

2014 ◽

Vol 113 (8) ◽

pp. 3105-3109 ◽

Cited By ~ 19

Author(s):

Venkatraman Pradeepa ◽

Subbiah Sathish-Narayanan ◽

Suyambulingam Arunachalam Kirubakaran ◽

Sengottayan Senthil-Nathan

Keyword(s):

Anopheles Stephensi ◽

Chemical Constituent ◽

Plumbago Zeylanica ◽

Malarial Vector

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Burn Wound Healing Activity of Ethanolic Extract of Acalypha indica in Oinment Formulated against Rabbits (Ocyctagus caniculus)

Asian Journal of Pharmaceutical Research and Development ◽

10.22270/ajprd.v8i3.740 ◽

2020 ◽

Vol 8 (3) ◽

pp. 18-20

Author(s):

Khairani Fitri ◽

Tetty Noverita Khairani ◽

Fajar Apollo Sinaga ◽

Amenia Gracia Talunohi

Keyword(s):

Wound Healing ◽

Ethanolic Extract ◽

Negative Control ◽

Burn Wound ◽

Leaf Extracts ◽

Laboratory Design ◽

Burn Wound Healing ◽

Healing Phase ◽

Wound Healing Activity ◽

Acalypha Indica

Objectives: The purpose of this study was to determine burn wound healing activity of Acalypha indica L. in oinment formulated. Design: This study uses an experimental laboratory design. This study used rabbits as test animals induced by burns with hot iron plates on the back. Extract ointment applied to the wound then observed the development of healing. Interventions: The extract was formulated in ointments with concentrations of 3, 5 and 7%. positive control used was ointment containing sesame oil and negative control used is an ointment base. Main outcome measure: The results showed a concentration of 3% had a slow and low effect, at a concentration of 5% it had a moderate healing phase, and a concentration of 7% had a good healing phase. Conclusion: The ointments containing Acalypha indica leaf extracts have good activity in healing burns in rabbits.

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