The study of apoptotic bifunctional effects in relationship between host and parasite in cystic echinococcosis: a new approach to suppression and survival of hydatid cyst

2011 ◽  
Vol 110 (5) ◽  
pp. 1979-1984 ◽  
Author(s):  
Adel Spotin ◽  
Monireh Mokhtari Amir Majdi ◽  
Mojtaba Sankian ◽  
Abdolreza Varasteh
Keyword(s):  
Hydatid Cyst ◽  
Cystic Echinococcosis ◽  
New Approach

scholarly journals Lymphocyte Populations in the Adventitial Layer of Hydatid Cysts in Cattle: Relationship With Cyst Fertility Status and Fasciola Hepatica Co-Infection

2019 ◽  
Vol 57 (1) ◽  
pp. 108-114 ◽  
Author(s):  
Mauricio Jiménez ◽  
Caroll Stoore ◽  
Christian Hidalgo ◽  
Felipe Corrêa ◽  
Marcela Hernández ◽  
...  
Keyword(s):  
Immune Response ◽  
B Cells ◽  
Hydatid Cyst ◽  
Cystic Echinococcosis ◽  
B Lymphocyte ◽  
Fasciola Hepatica ◽  
Hydatid Cysts ◽  
T And B Cells ◽  
Intermediate Hosts ◽  
Adventitial Layer

Cystic echinococcosis is a worldwide zoonosis caused by the cestode Echinococcus granulosus. Two types of hydatid cysts occur in intermediate hosts: fertile cysts that generate protoscoleces from the germinal layer of the cyst, and infertile cysts that do not produce protoscoleces and are unable to continue the life cycle of the parasite. The adventitial layer, a host-derived fibrous capsule surrounding the hydatid cyst, is suggested to play an important role in local immune regulation during infection and in fertility of the cysts. Fasciola hepatica, another important parasite of cattle, induces a characteristic Th2-like immune response that could modulate the immune response against E. granulosus. Natural co-infection of both parasites is common in cattle, but no reports describe the local immune response against E. granulosus with F. hepatica infection in the same host. This study analyzed the number and distribution of T and B cells in the adventitial layer of liver and lung cysts and the relationship with cyst fertility and F. hepatica co-infection. T lymphocytes were the predominant cell type in the adventitial layer of infertile hydatid cysts and were more numerous in infertile hydatid cysts. B lymphocyte numbers were not associated with hydatid cyst fertility. Mast cells were infrequent in the adventitial layer. The number of T and B cells was not associated with F. hepatica co-infection. The present study contributes to the understanding of local immune responses in bovine cystic echinococcosis.

scholarly journals Hydatid cyst fluid promotes peri-cystic fibrosis in cystic echinococcosis by suppressing miR-19 expression

2016 ◽  
Vol 9 (1) ◽  
Author(s):  
Chuanshan Zhang ◽  
Limin Wang ◽  
Tuergan Ali ◽  
Liang Li ◽  
Xiaojuan Bi ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Hydatid Cyst ◽  
Cystic Echinococcosis ◽  
Cyst Fluid ◽  
Hydatid Cyst Fluid

scholarly journals A New Approach for Treatment of Bone Hydatid Cyst Disease: A Case Report of Primer Femur Hydatid Cyst

2016 ◽  
Author(s):  
H Çabuk ◽  
AÇ Tekin ◽  
S Ayanoğlu ◽  
CD Büyükkurt ◽  
H Gürbüz ◽  
...  
Keyword(s):  
Case Report ◽  
Hydatid Cyst ◽  
New Approach

Cystic echinococcosis of the interventricular septum: a rare clinical presentation

2020 ◽  
Vol 30 (10) ◽  
pp. 1515-1516
Author(s):  
Erkan İriz ◽  
Semih Yaylı ◽  
Serdar Kula
Keyword(s):  
Public Health ◽  
Case Report ◽  
Hydatid Cyst ◽  
Echinococcus Granulosus ◽  
Cystic Echinococcosis ◽  
Clinical Presentation ◽  
Interventricular Septum ◽  
Health Concern ◽  
Public Health Concern ◽  
The World

AbstractCystic echinococcosis caused by infection with the larvae form of Echinococcus granulosus remains highly endemic and constitutes a public health concern in some regions of the world. In this case report, we present a rare children case of interventricular hydatid cyst with a size of approximately 5 cm and its successful treatment.

Screening of Cystic Echinococcosis and Toxocariasis in Urmia Municipal Workers, Northwest Iran

2020 ◽  
Vol 20 ◽  
Author(s):  
Negar Asadi ◽  
Khosrow Hazrati Tappeh ◽  
Iraj Mohebi ◽  
Elham Yousefi ◽  
Shahram Khademvatan
Keyword(s):  
Hydatid Cyst ◽  
Cystic Echinococcosis ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Toxocara Canis ◽  
Elisa Assay ◽  
Infectious Agents ◽  
Zoonotic Infection ◽  
Municipal Workers ◽  
Causative Agents

Background: Echinococcus granulosus and Toxocara spp. the causative agents of hydatid cyst and toxocariasis in human and animals, are zoonotic infection with medical and veterinary significance respectively. Aim: Herein, we aimed to investigate the seroprevalence of toxocariasis and cystic echinococcosis in Urmia municipal workers (gardeners and sweepers) in 2018 using ELISA assay. Objective: There is no precise report on the seroprevalence of toxocariasis and cystic echinococcosis in Urmia municipal workers using ELISA assay. Therefore, this study found an opportunity to investigate this subject. Methods: A total of 400 blood samples were obtained from municipal workers with average age of 41.31 ± 9.42. Commercial anti-Toxocara canis and hydatid cyst ELISA kits were used to assess the seroprevalence rates. Results: Approximately, 14.5% and 2.3% of individuals were seropositive for toxocariasis and hydatidosis, respectively. Consuming unboiled milk and/or raw/uncooked meat and rural conditions are risk factors for toxocariasis. Regarding hydatidosis, consuming unwashed vegetables was the only statistically significant risk factor. Toxocara infection (p = 0.01), but not hydatid cyst (p = 0.05), is more prevalent among sweepers than municipal gardeners. Conclusion: Due to the occupational condition of municipal workers, they’re exposed to many infectious agents; thus, more researches should be done on these populations.

scholarly journals Usefulness of Hydatid Cyst Fluid of Echinococcus granulosus Developed in Mice with Secondary Infection for Serodiagnosis of Cystic Echinococcosis in Humans

2002 ◽  
Vol 9 (3) ◽  
pp. 573-576 ◽  
Author(s):  
Wulamu Mamuti ◽  
Hiroshi Yamasaki ◽  
Yasuhito Sako ◽  
Kazuhiro Nakaya ◽  
Minoru Nakao ◽  
...  
Keyword(s):  
Hydatid Cyst ◽  
Echinococcus Granulosus ◽  
Host Species ◽  
Cystic Echinococcosis ◽  
False Positive ◽  
Secondary Infection ◽  
Cyst Fluid ◽  
Enzyme Linked Immunosorbent Assay ◽  
Tissue Homogenates ◽  
Hydatid Cyst Fluid

ABSTRACT The aim of this work was to assess the usefulness of hydatid cyst fluid (HCF) of Echinococcus granulosus, obtained from mice experimentally infected with hydatid cyst tissue homogenates, for the serodiagnosis of cystic echinococcosis (CE) in humans. The sensitivity and specificity of HCF obtained from mice for the detection of immunoglobulin G (IgG) antibodies in the sera of CE patients were compared with those of HCF from sheep and/or from a human CE patient by using immunoblotting (IB) and an enzyme-linked immunosorbent assay (ELISA). HCFs obtained from three different host species all were highly useful for immunoblotting, and sera from 19 (95%) of 20 CE patients equally recognized the antigen B subunit (approximately 8 kDa). HCF from mice showed a cross-reaction with 9 of 20 alveolar echinococcosis (AE) sera (45%), whereas HCFs from two other host species cross-reacted with 14 of the AE sera (70%). Although 2 (10%) of 20 sera from neurocysticercosis (NCC) patients were false positive with HCF from both sheep and humans, none of these sera showed a positive reaction with HCF from mouse origin. ELISAs with HCFs from both mouse and sheep origins detected all 20 CE and AE sera; however, these ELISAs showed 45% (9 of 20) and 60% (12 of 20) false-positive reactions with 20 NCC sera, respectively. The presence of nonspecific human IgG in HCF obtained from a CE patient prevented us from applying it to the ELISA. HCF of E. granulosus, obtained from laboratory mice with a secondary infection with hydatid cyst tissue homogenates, appears to be highly useful for the serodiagnosis of CE in humans and may be useful in domestic animals.

scholarly journals Treatment of hepatic cystic echinococcosis patients with clear cell renal carcinoma: a case report

2019 ◽  
Vol 14 (1) ◽  
pp. 647-650
Author(s):  
Bo Ran ◽  
Lujin Cheng ◽  
Lin Kang ◽  
Tuerganaili Aji ◽  
Tieming Jiang ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Hydatid Cyst ◽  
Cell Carcinoma ◽  
Cystic Echinococcosis ◽  
Renal Cell ◽  
Renal Carcinoma ◽  
Clear Cell ◽  
Clear Cell Renal Carcinoma ◽  
Echinococcal Cyst ◽  
Cell Renal Carcinoma

AbstractHuman cystic echinococcosis is a zoonosis caused by the larval cestode Echinococcus granulosus. Clear cell renal carcinoma is the most common pathological type of renal cell carcinoma. Echinococcosis complicated with carcinoma is rarely reported. Here, we reported a female patient with echinococcal cyst of the liver accompanied with clear cell renal carcinoma. This 27-year-old woman was admitted for abdominal pain. The serological testing of hydatid cyst was positive and levels of tumor markers were within the normal range. The computed tomography and histological findings confirmed hepatic echinococcal cyst complicated with renal carcinoma of kidney. Preoperative liver function was grade A. The patient underwent pericystectomy of liver hydatid cyst and partial nephrectomy. No recurrence was found at 1 year of follow-up. Liver hydatid complicated with renal cell carcinoma is rare, which should be differentiated from liver metastasis of renal cancer. Surgical resection is the optimal treatment. This case may provide insight for the diagnosis and research on the co-occurrence of tumor and hydatid cyst.

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