scholarly journals Spiritual well-being and health-related quality of life in colorectal cancer: a multi-site examination of the role of personal meaning

2010 ◽  
Vol 19 (6) ◽  
pp. 757-764 ◽  
Author(s):  
John M. Salsman ◽  
Kathleen J. Yost ◽  
Dee W. West ◽  
David Cella
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Well Being ◽  
Personal Meaning ◽  
Health Related Quality ◽  
Spiritual Well Being ◽  
Related Quality ◽  
Health Related

scholarly journals The Role of CT-Quantified Body Composition on Longitudinal Health-Related Quality of Life in Colorectal Cancer Patients: The Colocare Study

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1247
Author(s):  
Biljana Gigic ◽  
Johanna Nattenmüller ◽  
Martin Schneider ◽  
Yakup Kulu ◽  
Karen L. Syrjala ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Body Composition ◽  
First Year ◽  
Health Related Quality ◽  
Post Surgery ◽  
Related Quality ◽  
Health Related

Background: Obesity, defined by body mass index (BMI), measured at colorectal cancer (CRC) diagnosis has been associated with postoperative complications and survival outcomes. However, BMI does not allow for a differentiation between fat and muscle mass. Computed tomography (CT)-defined body composition more accurately reflects different types of tissue and their associations with health-related quality of life (HRQoL) during the first year of disease, but this has not been investigated yet. We studied the role of visceral and subcutaneous fat area (VFA and SFA) and skeletal muscle mass (SMM) on longitudinally assessed HRQoL in CRC patients. Methods: A total of 138 newly diagnosed CRC patients underwent CT scans at diagnosis and completed questionnaires prior to and six and twelve months post-surgery. We investigated the associations of VFA, SFA, and SMM with HRQoL at multiple time points. Results: A higher VFA was associated with increased pain six and twelve months post-surgery (β = 0.06, p = 0.04 and β = 0.07, p = 0.01) and with worse social functioning six months post-surgery (β = −0.08, p = 0.01). Higher SMM was associated with increased pain twelve months post-surgery (β = 1.03, p < 0.01). Conclusions: CT-quantified body composition is associated with HRQoL scales post-surgery. Intervention strategies targeting a reduction in VFA and maintaining SMM might improve HRQoL in CRC patients during the first year post-surgery.

scholarly journals Existential Well-Being and Health-Related Quality of Life in Young Adults

2020 ◽  
Vol 29 (4) ◽  
Author(s):  
Tara Gallien ◽  
Hui Bian ◽  
Juhee Kim ◽  
Ernest Tamanji Anye
Keyword(s):  
Quality Of Life ◽  
Young Adults ◽  
Well Being ◽  
Two Dimensions ◽  
Independent Effect ◽  
Health Related Quality ◽  
Spiritual Well Being ◽  
Related Quality ◽  
Health Related

The aim of this study was to determine the independent effect of existential well-being (EWB) and religious well-being (RWB), two dimensions of spiritual well-being, on various measures of health related quality of life (HQROL) in a sample of 804 young adults. Independent variables were measured using the EWB and RWB subscales of the Spiritual Well-Being Scale; dependent variables were measured using questions from the Centers for Disease Control and Prevention's HRQOL – 14 Measure. Linear and ordinal regression results found stronger associations of EWB, compared to RWB, with increased overall HQROL, more healthy days and fewer unhealthy days, and better general health status, respectively.

Health-related quality of life and time from diagnosis among young adult colorectal cancer survivors.

2021 ◽  
Vol 39 (3_suppl) ◽  
pp. 34-34
Author(s):  
Kimberly Ann Miller ◽  
Julia Stal ◽  
Phuong Gallagher ◽  
Jonathan N Kaslander ◽  
David R. Freyer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Online Survey ◽  
Well Being ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Targeted Interventions ◽  
Related Quality ◽  
Health Related

34 Background: Incidence of colorectal cancer (CRC) in patients under 50 years of age is rising. Quality of life in survivorship is not well-described in this population. We compared health-related quality of life (HRQoL) in CRC survivors ≤ 50 years old who were 6-18 months or 19-36 months from initial diagnosis or relapse. Methods: A cross-sectional online survey was administered in collaboration with a national organization for young CRC survivors. The Functional Assessment of Cancer Therapy (FACT-C) was used to measure HRQoL, which assesses HRQoL globally, including a CRC specific scale, and emotional, physical, social, and functional well-being domains. T-tests were conducted to compare HRQoL between survivors who were 6-18 months versus 19-36 months from diagnosis/relapse. Results: This sample (n=308) had a mean age of 33.76 SD±6.68; 201 (65.3%) were male; tumor location was colon or rectal in 41.7% and 58.3%, respectively. The majority (55.23%) were diagnosed with stage 2 disease; 98.0% were non-metastatic. 42.2% experienced relapse; 25% had an ostomy. Most survivors were 6-18 months (N=189; 61.4%) from diagnosis/relapse, and key demographics and disease characteristics did not significantly differ between those who were shorter versus longer time from diagnosis/relapse. The mean global HRQoL score was 67.3 out of a possible score of 136. Across domains, scores were low, with social well-being the highest (15.15/28) and emotional well-being the lowest (11.44/24). Social well-being was significantly higher among survivors who were 6-18 months from diagnosis/relapse compared to those 19-36 months (15.98 for 6-18 months vs. 13.83 for 19-36; p<0.01), as was functional well-being (13.20 for 6-18 months vs. 11.12 for 19-36; p<0.01). Emotional well-being and physical well-being did not significantly differ between groups. Conclusions: Overall HRQoL scores were low among younger CRC survivors, and social and functional well-being were significantly worse for those longer from diagnosis. Appropriate counseling and other targeted interventions are necessary to maintain HRQoL over time in this at-risk population. [Table: see text]

scholarly journals Time from Diagnosis and Correlates of Health-Related Quality of Life among Young Adult Colorectal Cancer Survivors

Cancers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 4045
Author(s):  
Kimberly A. Miller ◽  
Julia Stal ◽  
Phuong Gallagher ◽  
Zhen Weng ◽  
David R. Freyer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Young Adult ◽  
Online Survey ◽  
Well Being ◽  
Disease Stage ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

The incidence of colorectal cancer (CRC) is rising among young adults. Health-related quality of life (HRQoL) in survivorship is not well-described in this population. We assessed HRQoL among young adult CRC survivors diagnosed from age 18–39 (AYAs) to examine differences by time from diagnosis, and to identify key correlates. A cross-sectional online survey was administered in collaboration with a national patient advocacy organization. The Functional Assessment of Cancer Therapy (FACT-C) was used to measure HRQoL, which assesses HRQoL globally and across 4 domains: emotional, physical, social, and functional. T-tests were conducted to compare HRQoL between survivors who were 6–18 months versus 19–36 months from diagnosis or relapse and multiple linear regression was conducted to identify correlates. The sample (n = 196) had a mean age of 32.2(SD ± 4.5); 116 (59.9%) were male; and the self-reported tumor location was colon (39.3%) or rectal (60.7%). The majority (56.4%) were diagnosed with stage 2 disease; 96.9% were non-metastatic. The mean global HRQoL score was 67.7 out of a possible score of 136. Across domains, mean scores were low. Emotional and physical well-being were significantly higher among survivors who were 19–36 months from diagnosis/relapse compared to those 6–18 months from diagnosis/relapse. Longer time from diagnosis and older current age were associated with higher HRQoL, while more intensive treatment and higher clinical disease stage were negatively associated, particularly in the emotional and physical domains. Overall, HRQoL was low in this population, and further research is needed to inform age-appropriate interventions to improve HRQoL for AYA CRC survivors.

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