The relationship between mindfulness, pain intensity, pain catastrophizing, depression, and quality of life among cancer survivors living with chronic neuropathic pain

2016 ◽  
Vol 24 (10) ◽  
pp. 4167-4175 ◽  
Author(s):  
Patricia A. Poulin ◽  
Heather C. Romanow ◽  
Noriyeh Rahbari ◽  
Rebecca Small ◽  
Catherine E. Smyth ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Neuropathic Pain ◽  
Cancer Survivors ◽  
Pain Intensity ◽  
Pain Catastrophizing ◽  
Chronic Neuropathic Pain ◽  
The Relationship

scholarly journals The Effect of Repeated Electroacupuncture Analgesia on Neurotrophic and Cytokine Factors in Neuropathic Pain Rats

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Junying Wang ◽  
Yonghui Gao ◽  
Shuping Chen ◽  
Chenlin Duanmu ◽  
Jianliang Zhang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Pain ◽  
Neuropathic Pain ◽  
Neurotrophic Factors ◽  
Quantitative Real Time Pcr ◽  
Chronic Neuropathic Pain ◽  
Elevated Expression ◽  
Chronic Constrictive Injury ◽  
The Relationship

Chronic pain is a common disability influencing quality of life. Results of previous studies showed that acupuncture has a cumulative analgesic effect, but the relationship with spinal cytokines neurotrophic factors released by astrocytes remains unknown. The present study was designed to observe the effect of electroacupuncture (EA) treatment on spinal cytokines neurotrophic factors in chronic neuropathic pain rats. The chronic neuropathic pain was established by chronic constrictive injury (CCI). EA treatment was applied at Zusanli (ST36) and Yanglingquan (GB34) (both bilateral) once a day, for 30 min. IL-1βmRNA, TNF-αmRNA, and IL-1 mRNA were detected by quantitative real-time PCR, and the proteins of BDNF, NGF, and NT3/4 were detected by Western blot. The expression levels of cytokines such as IL-1βmRNA, TNF-αmRNA, IL-6 mRNA, and neurotrophic factors such as BDNF, NGF, and NT3/4 in the spinal cord were increased significantly after CCI. The astrocytes released more IL-1βand BDNF after CCI. Repeated EA treatment could suppress the elevated expression of IL-1βmRNA, TNFαmRNA, and BDNF, NGF, and NT3/4 but had no effect on IL-6 mRNA. It is suggested that cytokines and neurotrophic factors which may be closely associated with astrocytes participated in the process of EA relieving chronic pain.

scholarly journals Pain and Its Consequences in Quality of Life: A Study with WHOQOL-Bref in Leprosy Patients with Neuropathic Pain

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Felipe J. J. Reis ◽  
Maria Katia Gomes ◽  
Jéssica Rodrigues ◽  
Artur Padão Gosling ◽  
Ana Paula Fontana ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Neuropathic Pain ◽  
Pain Intensity ◽  
Negative Influence ◽  
Chronic Neuropathic Pain ◽  
Rehabilitation Programs ◽  
Recreation Opportunities ◽  
Leprosy Patients ◽  
Pain Patients

Chronic neuropathic pain emerges as a challenge in the treatment of leprosy patients after multidrug therapy discharge. The aim of this study was to determine the quality of life and its repercussions in leprosy patients with chronic pain. We studied male and female patients with chronic neuropathic pain in the last year. Neuropathic pain was confirmed using Douleur Neuropathique en 4 (DN4) and its intensity evaluated by visual analogue scale (VAS). A general questionnaire was applied to evaluate quality of life (WHOQOL-bref). Statistical analyses were composed by descriptive and central tendency. Spearman correlation was used to identify the relation between pain intensity, quality of life domains, and facets. Multiple linear regressions were performed to verify the influence of pain intensity on each facet. Neuropathic pain patients scored worst in physical and environment domains. The low facets were related to pain and discomfort, thinking and concentration, sexual activity, and recreation opportunities. Pain intensity has a high negative influence on psychological domain and recreation opportunities. These findings should contribute to the development of rehabilitation programs considering patients needs to improve their quality of life and true social reintegration.

scholarly journals Predictors for Persistent Neuropathic Pain – A Delphi Survey

2011 ◽  
Vol 6;14 (6;12) ◽  
pp. 559-568
Author(s):  
Sabine Boogaard
Keyword(s):  
Quality Of Life ◽  
Neuropathic Pain ◽  
Delphi Study ◽  
Pain Catastrophizing ◽  
Patient Characteristics ◽  
Health Related Quality ◽  
Chronic Neuropathic Pain ◽  
Related Quality ◽  
Health Related

Background: Chronic neuropathic pain has a major effect on quality of life. In order to prevent neuropathic pain from becoming chronic and improve neuropathic pain care, it is important to identify predictors associated with the persistence of neuropathic pain. Objective: To identify potential predictors associated with the persistence of neuropathic pain. Study Design: A 2-round Delphi study. Setting: University Medical Center and Pain Management Research Center Methods: A 2-round Delphi study was conducted among 17 experts in the field of neuropathic pain. Selection of the panel was based on the citation index ranking for neuropathic pain-related research and/or membership in the neuropathic pain special interest group of the International Association for the Study of Pain (IASP), complemented with experts with demonstrated field knowledge. Potential predictors were categorized according to the International Classification of Functioning, Disability and Health model. Participants were asked to identify important predictors, suggest new predictors, and grade the importance on a 0-10 scale. For the second round, predictors were considered important if the median score was ≥ 7 and the interquartile range (IQR) ≤ 3. Results: In the first round, 20 predictors were selected and 58 were added by the experts (patient characteristics [15], environmental factors [25], functions & structure [4], participation & health related quality of life [14]). In the second round, 12 predictors were considered important (patient characteristics [4; e.g., depression, pain catastrophizing], environmental factors [surgery as treatment for neuropathic pain], functions & structure [6; e.g., allodynia, duration of the complaints], participation & trait anxiety/depression as a part of health related quality of life). Presence of depression and pain catastrophizing were considered the most important predictors for chronic neuropathic pain (median ≥ 8;IQR ≤ 2). Limitations: The study design did not include plenary discussion among the experts. The meaning of the individual topics used in this study could have been subject to interpretation bias. Conclusions: Overall, psychological factors and factors related to sensory disturbances were considered important predictors for persistence of neuropathic pain. Activity related factors and previously received paramedical and alternative treatment were considered to be less important. The list of possible predictors obtained by this study may serve as a basis for development of a clinical prediction rule for chronic neuropathic pain. Key words: Neuropathic pain, chronic pain, persistence, Delphi study, opinion, predictors, ICF model.

Pain Catastrophizing Is Independently Associated with Quality of Life in Patients with Severe Hip Osteoarthritis

Pain Medicine ◽  
2018 ◽  
Vol 20 (11) ◽  
pp. 2220-2227 ◽  
Author(s):  
Kazuhiro Hayashi ◽  
Takkan Morishima ◽  
Tatsunori Ikemoto ◽  
Hirofumi Miyagawa ◽  
Takuya Okamoto ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Pain Intensity ◽  
Gait Speed ◽  
Pain Catastrophizing ◽  
Hip Osteoarthritis ◽  
Cross Sectional ◽  
Japanese Orthopedic Association ◽  
Affected Side ◽  
Tertiary Center

AbstractObjective. Pain catastrophizing is an important pain-related variable, but its impact on patients with osteoarthritis is uncertain. The aim of the current study was to determine whether pain catastrophizing was independently associated with quality of life (QOL) in patients with osteoarthritis of the hip. Design. Cross-sectional study conducted between June 2017 and February 2018. Setting. Tertiary center. Subjects. Seventy consecutively enrolled patients with severe hip osteoarthritis who had experienced pain for six or more months that limited daily function, and who were scheduled for primary unilateral total hip arthroplasty. Methods. QOL was measured using the EuroQOL-5 Dimensions questionnaire, the Japanese Orthopedic Association Hip Disease Evaluation Questionnaire, and a dissatisfaction visual analog scale. Covariates included pain intensity, pain catastrophizing, range of hip motion, and gait speed. The variables were subjected to multivariate analysis with each QOL scale. Results. The median age was 68 years, and the median Pain Catastrophizing Scale score was 26. In multiple regression analysis, pain catastrophizing, pain intensity in both hips, pain intensity on the affected side, hip flexion on the affected side, and gait speed were independently correlated with QOL. Conclusions. Pain catastrophizing was independently associated with each QOL scale in preoperative patients with severe hip osteoarthritis. Pain catastrophizing had either the strongest or second strongest effect on QOL, followed by pain intensity.

scholarly journals Quality of life of testicular cancer survivors and the relationship with sociodemographics, cancer-related variables, and life events

2005 ◽  
Vol 14 (3) ◽  
pp. 251-259 ◽  
Author(s):  
J. Fleer ◽  
H. J. Hoekstra ◽  
D. T. Sleijfer ◽  
M. A. Tuinman ◽  
E. C. Klip ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Testicular Cancer ◽  
Cancer Survivors ◽  
Life Events ◽  
Testicular Cancer Survivors ◽  
The Relationship

scholarly journals EFFECTIVENESS OF GABAPENTIN USAGE TOWARD REDUCING PAIN INTENSITY LEVEL AND QUALITY OF LIFE OF POST-STROKE NEUROPATHIC PATIENTS IN REGIONAL GENERAL HOSPITAL, WEST NUSA TENGGARA PROVINCE YEAR 2018

2019 ◽  
pp. 560-562
Author(s):  
NURUL QIYAAM ◽  
WIRAWAN ADIKUSUMA ◽  
BAIQ LENY NOPITASARI ◽  
TRI MURTI ANDAYANI ◽  
AULIA AMINI
Keyword(s):  
Quality Of Life ◽  
Neuropathic Pain ◽  
Pain Intensity ◽  
General Hospital ◽  
Intensity Level ◽  
Post Stroke ◽  
Provincial Hospital ◽  
Before And After ◽  
June July

Objective: Stroke is defined as a sudden loss of brain function due to blockade/rupture of the brain’s blood vessels. Data collected by the Indonesian Stroke Foundation show that Indonesia ranks first in Asia as the country with the highest number of stroke sufferers. The purpose of this study was to determine the effectiveness of the use of gabapentin to reduce pain intensity and improve the quality of life of post-stroke neuropathic pain in NTB Province hospital patients. Methods: This study was carried out in the period of June–July 2018. The targeted population was all post-stroke neuropathic patients who received gabapentin therapy in NTB provincial hospital. Affordable populations are post-stroke neuropathic pain patients who seek outpatient treatment at NTB provincial hospital that meets the inclusion and exclusion criteria. The results of the data will be analyzed using paired sample t-test. Obtained 15 patients were willing to participate in this study. Results: The results of the study using questionnaire EQ-5D-3L after using gabapentin for 2 weeks. Patients experienced an improvement in the quality of life in each dimension items, namely the ability to walk/move from 6.7%, no problem to 60%, no self-care, 26.7% no problem to be 80% without problems, usual activities carried out from 13.3% had no problems to 46.7% had no problems, feeling of pain/discomfort from 60% having moderate problems to 60% had no problems, and anxiety/depression of 60% had no problem being 100% has no problem. While the measurement of the quality of life using the EQ-VAS questionnaire, there was a significant improvement in the quality of life between before and after using gabapentin at 32.66. Conclusion: The use of gabapentin has effectiveness on reduction of pain intensity and the quality of life of post-stroke neuropathic patients in regional general hospital, West Nusa Tenggara Province year 2018.

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