Death causes and pathogens analysis of systemic lupus erythematosus during the past 26 years

2013 ◽  
Vol 33 (1) ◽  
pp. 57-63 ◽  
Author(s):  
Yunyun Fei ◽  
Xiaochun Shi ◽  
Fengying Gan ◽  
Xuemei Li ◽  
Wen Zhang ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
The Past ◽  
Death Causes

Stem cell transplantation: progress in Asia

Lupus ◽  
2010 ◽  
Vol 19 (12) ◽  
pp. 1468-1473 ◽  
Author(s):  
L. Sun
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Hematopoietic Stem ◽  
The Past ◽  
Complex Autoimmune Disease ◽  
Significant Mortality

Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multiorgan involvement and high mortality, which was reduced because of the most widely and classically used immunosuppressive therapies. However, some patients continue to have significant mortality. So a shift in the approach to the treatment of SLE is needed. In the past decade, most transplants have been performed in the treatment of SLE with allogeneic or autologous hematopoietic stem cells and currently emerging mesenchymal stem cells. There are some important differences between the two procedures.

scholarly journals Hydroxychloroquine

2020 ◽  
Vol 0 ◽  
pp. 1-7
Author(s):  
C. B. Sindhu ◽  
Sandhya George ◽  
Anita Sankar ◽  
Valsa Stephen
Keyword(s):  
Rheumatoid Arthritis ◽  
Systemic Lupus Erythematosus ◽  
Adverse Effects ◽  
Drug Administration ◽  
Lupus Erythematosus ◽  
Food And Drug Administration ◽  
Systemic Lupus ◽  
The Past ◽  
Related Drug

Hydroxychloroquine (HCQ) and its related drug, chloroquine, have been under use for malaria for the past 75 years. Its use for malaria, rheumatoid arthritis and systemic lupus erythematosus are Food and Drug Administration (FDA) approved. These drugs have immunomodulatory and antiviral actions. More and more indications for this drug are being explored. These drugs are still under study as possible treatments for coronavirus disease 2019 but at present FDA has revoked its emergency use authorization for these two drugs. However, in many other indications, HCQ is a valuable drug but monitoring for adverse effects is mandatory.

scholarly journals Pseudo-pseudo Meigs’ syndrome: a rare presentation of systemic lupus erythematosus

Reumatismo ◽  
2019 ◽  
Vol 71 (2) ◽  
pp. 108-112 ◽  
Author(s):  
G. Tansir ◽  
P. Kumar ◽  
A. Pius ◽  
S.K. Sunny ◽  
M. Soneja
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Pleural Effusion ◽  
Autoimmune Disease ◽  
Lupus Erythematosus ◽  
Abdominal Distension ◽  
Ca 125 ◽  
Systemic Lupus ◽  
Rare Presentation ◽  
The Past ◽  
History Of

Systemic lupus erythematosus (SLE) is a chronic inflammatory multisystem autoimmune disease. Ascites when associated with pleural effusion and raised CA-125 levels in SLE patient, is known as pseudo-pseudo Meigs’ syndrome (PPMS). This is the case of a 22-year-old lady who presented with complaints of abdominal distension for one month and had a history of spontaneous abortion in the past. Abdominal imaging did not reveal any tumor and after extensive workup a diagnosis of PPMS was made. She was successfully treated with steroids, hydroxychloroquine and cyclophosphamide.

scholarly journals Immunomodulatory Effect of MSCs and MSCs-Derived Extracellular Vesicles in Systemic Lupus Erythematosus

2021 ◽  
Vol 12 ◽  
Author(s):  
Chunjuan Yang ◽  
Jianmei Sun ◽  
Yipeng Tian ◽  
Haibo Li ◽  
Lili Zhang ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Extracellular Vesicles ◽  
Lupus Erythematosus ◽  
Biological Therapy ◽  
Systemic Lupus ◽  
Innate And Adaptive Immunity ◽  
The Past ◽  
Underlying Mechanisms ◽  
Unclear Etiology ◽  
Insight Into

Systemic lupus erythematosus (SLE) is a common autoimmune connective tissue disease with unclear etiology and pathogenesis. Mesenchymal stem cell (MSC) and MSC derived extracellular vesicles (EVs) play important roles in regulating innate and adaptive immunity, which are involved in many physiological and pathological processes and contribute to the immune homeostasis in SLE. The effects of MSCs and EVs on SLE have been drawing more and more attention during the past few years. This article reviews the immunomodulatory effects and underlying mechanisms of MSC/MSC-EVs in SLE, which provides novel insight into understanding SLE pathogenesis and guiding the biological therapy.

scholarly journals DEPRESI INDUCED STEROID: STUDI KASUS

2019 ◽  
Vol 1 (2) ◽  
pp. 1-4
Author(s):  
Saiful Batubara
Keyword(s):  
Rheumatoid Arthritis ◽  
Systemic Lupus Erythematosus ◽  
Immune Response ◽  
Depressed Mood ◽  
Lupus Erythematosus ◽  
Natural Disturbance ◽  
Systemic Lupus ◽  
The Past ◽  
Back Ground

Back Ground: Depression is a natural disturbance of feeling that is characterized by feelings of sadness, loss of interest and easily tired. Steroids are drugs that can reduce swelling, pain and heat due to inflammation through reducing the immune response. Steroids are often used in cases of systemic Lupus Erythematosus in the long term. Therefore management of the disease must be done well because steroids can cause depression. Case Report:Women, 37 years old, depressed mood, disappointment in life, loss of enthusiasm, fatigue, decreased appetite and difficulty sleeping for 1 year. 4 years ago I took steroids for 2 years at a dose of 20mg / day, because rheumatoid arthritis was stopped by os, and for the past 1 year, steroid consumption was due to Systemic Lupus Erythematosus around 60 mg / day. . Before the os consumes steroids, the OS has never experienced depression.BP: 110/70 mmHg , HR 88x/menit, RR 20x/menit, Temp 37°C. Skor BDI 21. Laboratorium Hb 11,8 g/dl, Leukosit 7500/mm3, trombosit 201.000/mm3,,Kalium 2,8, KGDad 99 mg/dlSGOT 29 ,SGPT32, Ureum 15,78 mg/dl, Creatinin 0,65 mg/dl.  Tot Colesterol 198mg/dl,  LDL 128 mg/dl, HDL 35 mg/dl Fototoraks : Jantung dan Parudalambatas normal, FotoLumbosakral : SpondilosisLumbalis. The patient is diagnosed with depression. Given psychotherapy, sandepril 2 x 25 mg for 3 months. Patients show clinical improvement marked by reduced sadness and can understand the disease. Conclusion :Steroid-induced depression has been reported after psychotherapy and sandepril 2 x 25 mg of the patient's condition showed improvement.

The Kidney Biopsy in Systemic Lupus Erythematosus: A View of the Past and a Vision of the Future

2019 ◽  
Vol 26 (5) ◽  
pp. 360-368 ◽  
Author(s):  
Isabelle Ayoub ◽  
Clarissa Cassol ◽  
Salem Almaani ◽  
Brad Rovin ◽  
Samir V. Parikh
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Kidney Biopsy ◽  
Systemic Lupus ◽  
The Past ◽  
The Future

scholarly journals Long-Term Survival and Death Causes of Systemic Lupus Erythematosus in China

Medicine ◽  
2015 ◽  
Vol 94 (17) ◽  
pp. e794 ◽  
Author(s):  
Ziqian Wang ◽  
Yanhong Wang ◽  
Rongrong Zhu ◽  
Xinping Tian ◽  
Dong Xu ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Term Survival ◽  
Long Term Survival ◽  
Death Causes

Lupus Erythematosus, A Review of the Current Status of Discoid and Systemic Lupus Erythematosus and Their Variants

PEDIATRICS ◽  
1966 ◽  
Vol 38 (3) ◽  
pp. 531-531
Author(s):  
FRED S. ROSEN
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Current Knowledge ◽  
Current Status ◽  
Systemic Lupus ◽  
The Past ◽  
The Subject

Despite the productive investigations on lupus erythematosus during the past decade, this protean disease remains a baffling problem which eludes definition. The current knowledge on the subject has been assembled in a big and beautiful book by the editor. The first part of the book deals with the pathology of lupus. Several subsequent chapters by Mackay, the Mieschers, and others bring together current immunological concepts about this puzzling disease. The last two thirds of the book are devoted to a description of over 400 patients with lupus based on the editor's broad experience with this malady

scholarly journals The Wolf’(s)-B(r)ain- The Past, Present, Future of CNS Lupus

2019 ◽  
Vol 16 (3) ◽  
pp. 6-14
Author(s):  
Murali Suhas ◽  
Srikanteshwara Parveen-Kumar
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Review Article ◽  
Future Research ◽  
Systemic Lupus ◽  
Research Directions ◽  
Cns Lupus ◽  
The Past ◽  
The Future ◽  
Future Research Directions

Systemic Lupus Erythematosus is a long-studied condition with protean manifestations, yet, with so much known about the pathogenesis and treatment aspects still in the dark. In this review article, we try to sum up all the knowledge we have till date, the practice essentials used to date and the future research directions, all of which ultimately lead to a better understanding of the disease and its management.

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