Chromatographic Separation of Bupivacaine Enantiomers by HPLC: Parameters Estimation of Equilibrium and Mass Transfer Under Linear Conditions

Adsorption ◽  
2005 ◽  
Vol 11 (2) ◽  
pp. 123-129 ◽  
Author(s):  
Ivanildo José Da Silva ◽  
Vinícius De Veredas ◽  
Marcos José Souza Carpes ◽  
Cesar Costapinto Santana
Keyword(s):  
Mass Transfer ◽  
Chromatographic Separation ◽  
Parameters Estimation

scholarly journals Freeze-Drying Kinetics Approach of Soluble Coffee. Mass Transfer Parameters Estimation

2017 ◽  
Vol 62 (1) ◽  
pp. 7-17
Author(s):  
Adina Ghirişan ◽  
◽  
Simion Drăgan ◽  
Vasile Miclăuş ◽  
◽  
...  
Keyword(s):  
Mass Transfer ◽  
Freeze Drying ◽  
Drying Kinetics ◽  
Parameters Estimation ◽  
Transfer Parameters ◽  
Soluble Coffee

scholarly journals Equilibrium and mass transfer parameters estimation of the products of synthesis of piperonal by high performance liquid chromatography

2015 ◽  
Vol 1 (1) ◽  
pp. 01-15
Author(s):  
Alex Martins Ramos ◽  
Marco Aurélio Cremasco
Keyword(s):  
Mass Transfer ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Stationary Phase ◽  
High Performance ◽  
Multicomponent Mixture ◽  
Effective Diffusion ◽  
Internal Resistance ◽  
Parameters Estimation ◽  
Parallel Diffusion

The reaction sequences applied to essential oil of Piper hispidinervum D.C (long pepper) leads to formation of a multicomponent mixture composed, mainly, by piperonal, safrole, isosafrole and terpinolene. Due to importance of the piperonal for the pharmaceutical industry is that proposed separate it by high performance liquid chromatography. In this paper, it was studied the adsorption and mass transfer phenomena of these compounds using ethanol/water 70/30 (v/v) as mobile phase and C18 as stationary phase at 35 oC. Regarding to adsorption, the piperonal is the component that has the lowest affinity and terpinolene, the greatest with stationary phase. Regarding to mass transfer, effective diffusion and axial dispersion coefficients were around 10- (10 to 11) and 10- (7 to 8) m2.s-1, respectively. The internal resistance to mass transfer controls the overall mass transfer and parallel diffusion model describes the intra-particle transport mechanism.

A Diffusion Cell for the Mass Transfer Investigation in the Solid Porous Media

2018 ◽  
Vol 17 (5) ◽  
Author(s):  
Alexey Zhokh ◽  
Andrey Trypolskyi ◽  
Peter Strizhak
Keyword(s):  
Mass Transfer ◽  
Porous Media ◽  
Mass Balance ◽  
Porous Silica ◽  
Parameters Estimation ◽  
Diffusion Cell ◽  
Gas Chromatograph ◽  
Balance Equations ◽  
Absorbing Boundary ◽  
The Impact

Abstract A diffusion cell for the mass transfer investigation of the gases through the solid porous media is developed. The diffusion cell may be configured in two different ways. One configuration corresponds to the reflecting boundary condition, whereas another configuration satisfies the absorbing boundary. The mass balance equations for different cell configurations are provided. The mass balance equations are applicable for the calculations of the diffusate quantity decays. The latter are suitable for the mass transfer parameters estimation using the solutions of the transport equations, obtained for the boundary conditions that correspond to the diffusion cell configurations. Accounting for the impact of the apparatus function of the diffusion cell on the experimental data is also revisited. In addition, the practical use of the diffusion cell based on the installation of the cell into the gas chromatograph for the investigation of the methane transport through the porous silica pellet as an example is demonstrated.

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