scholarly journals New strategy of controlled, stepwise release from novel MBioF and its potential application for drug delivery systems

Adsorption ◽  
2019 ◽  
Vol 25 (3) ◽  
pp. 383-391 ◽  
Author(s):  
Adam Bieniek ◽  
Marek Wiśniewski ◽  
Katarzyna Roszek ◽  
Paulina Bolibok ◽  
Artur P. Terzyk ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Potential Application ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
New Strategy

scholarly journals Trends in Degradable Mesoporous Organosilica-Based Nanomaterials for Controlling Drug Delivery: A Mini Review

Materials ◽  
2020 ◽  
Vol 13 (17) ◽  
pp. 3668 ◽  
Author(s):  
Vanessa Poscher ◽  
Yolanda Salinas
Keyword(s):  
Drug Delivery ◽  
Clinical Trials ◽  
Potential Application ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Cellular Level ◽  
On Demand ◽  
Mesoporous Organosilica ◽  
Molecular Gates ◽  
Potential Use

The last few years of enhancing the design of hybrid mesoporous organosilica nanoparticleshas allowed their degradation under specific pathologic conditions, which finally is showing a lightin their potential use as drug delivery systems towards clinical trials. Nevertheless, the issueof controlling the degradation on-demand at cellular level still remains a major challenge, even if ithas lately been addressed through the incorporation of degradable organo-bridged alkoxysilanesinto the silica framework. On this basis, this mini review covers some of the most recent examplesof dierent degradable organosilica nanomaterials with potential application in nanomedicine,from degradable non-porous to mesoporous organosilica nanoparticles (MONs), functionalized withresponsive molecular gates, and also the very promising degradable periodic mesoporous organosilicamaterials (PMOs) only consisting of organosilica bridges.

Marine sponge-derived/inspired drugs and their applications in drug delivery systems

2021 ◽  
Vol 13 (5) ◽  
pp. 487-504
Author(s):  
Avin Ramanjooloo ◽  
Raymond J Andersen ◽  
Archana Bhaw-Luximon
Keyword(s):  
Drug Delivery ◽  
Natural Products ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Marine Sponges ◽  
Clinical Use ◽  
Drug Candidates ◽  
New Strategy ◽  
Terrestrial Habitats ◽  
Potential Use

Oceans harbor a vast biodiversity that is not represented in terrestrial habitats. Marine sponges have been the richest source of marine natural products reported to date, and sponge-derived natural products have served as inspiration for the development of several drugs in clinical use. However, many promising sponge-derived drug candidates have been stalled in clinical trials due to lack of efficacy, off-target toxicity, metabolic instability or poor pharmacokinetics. One possible solution to this high clinical failure rate is to design drug delivery systems that deliver drugs in a controlled and specific manner. This review critically analyzes drugs/drug candidates inspired by sponge natural products and the potential use of drug delivery systems as a new strategy to enhance the success rate for translation into clinical use.

Transforming stealthy to sticky nanocarriers: a potential application for tumor therapy

2019 ◽  
Vol 7 (9) ◽  
pp. 3581-3593 ◽  
Author(s):  
Alidha Gafur ◽  
Natalia Kristi ◽  
Ali Maruf ◽  
Guixue Wang ◽  
Zhiyi Ye
Keyword(s):  
Drug Delivery ◽  
Potential Application ◽  
Drug Delivery Systems ◽  
Tumor Therapy ◽  
Delivery Systems

Recently, chameleon-like drug delivery systems have shown great potential in achieving simultaneous stealthy and sticky surfaces of nanocarriers to target/retarget tumors.

scholarly journals Poly(methyl vinyl ether-co-maleic acid) Hydrogels Containing Cyclodextrins and Tween 85 for Potential Application as Hydrophobic Drug Delivery Systems

2019 ◽  
Vol 27 (4) ◽  
pp. 396-403 ◽  
Author(s):  
Eneko Larrañeta ◽  
Juan Domínguez-Robles ◽  
Martha Coogan ◽  
Emma Heaney ◽  
Sarah A. Stewart ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Vinyl Ether ◽  
Maleic Acid ◽  
Potential Application ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Hydrophobic Drug ◽  
Methyl Vinyl ◽  
Methyl Vinyl Ether

Polymer based nanoparticles for biomedical applications by microfluidic techniques: from the design to the biological evaluation

2021 ◽  
Author(s):  
assunta borzacchiello ◽  
Antonio Fabozzi ◽  
Francesca Della Sala ◽  
Mario di Gennaro ◽  
Nicola Solimando ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Physicochemical Properties ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
Biological Evaluation ◽  
Delivery Systems ◽  
Test Drug ◽  
New Strategy

The development of microfluidic technologies represents a new strategy to produce and test drug delivery systems. Particularly microfluidics can facilitate the development of new nanoparticles-based systems with controlled physicochemical properties...

Techniques For The Preparation of Tissue Samples Containing Injectable Polymer Microcapsules

1985 ◽  
Vol 43 ◽  
pp. 710-711
Author(s):  
G.E. Visscher ◽  
R. L. Robison ◽  
G. J. Argentieri
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Gastrocnemius Muscle ◽  
Degradation Process ◽  
Delivery Systems ◽  
Tissue Reaction ◽  
Electron Microscopic ◽  
Tissue Samples ◽  
Injectable Polymer ◽  
Microscopic Techniques

The use of various bioerodable polymers as drug delivery systems has gained considerable interest in recent years. Among some of the shapes used as delivery systems are films, rods and microcapsules. The work presented here will deal with the techniques we have utilized for the analysis of the tissue reaction to and actual biodegradation of injectable microcapsules. This work has utilized light microscopic (LM), transmission (TEM) and scanning (SEM) electron microscopic techniques. The design of our studies has utilized methodology that would; 1. best characterize the actual degradation process without artifacts introduced by fixation procedures and 2. allow for reproducible results.In our studies, the gastrocnemius muscle of the rat was chosen as the injection site. Prior to the injection of microcapsules the skin above the sites was shaved and tattooed for later recognition and recovery. 1.0 cc syringes were loaded with the desired quantity of microcapsules and the vehicle (0.5% hydroxypropylmethycellulose) drawn up. The syringes were agitated to suspend the microcapsules in the injection vehicle.

Sign in / Sign up

Export Citation Format

Share Document