scholarly journals Drug Use Mediates the Relationship Between Depressive Symptoms and Adherence to ART Among Recently Incarcerated People Living with HIV

2018 ◽  
Vol 23 (8) ◽  
pp. 2037-2047 ◽  
Author(s):  
Lauren M. Hill ◽  
Carol E. Golin ◽  
Nisha C. Gottfredson ◽  
Brian W. Pence ◽  
Bethany DiPrete ◽  
...  
10.2196/20847 ◽  
2020 ◽  
Vol 8 (10) ◽  
pp. e20847
Author(s):  
Yu Zeng ◽  
Yan Guo ◽  
Linghua Li ◽  
Y Alicia Hong ◽  
Yiran Li ◽  
...  

Background Associations between higher levels of patient engagement and better health outcomes have been found in face-to-face interventions; studies on such associations with mobile health (mHealth) interventions have been limited and the results are inconclusive. Objective The objective of this study is to investigate the relationship between patient engagement in an mHealth intervention and depressive symptoms using repeated measures of both patient engagement and patient outcomes at 4 time points. Methods Data were drawn from a randomized controlled trial (RCT) of an mHealth intervention aimed at reducing depressive symptoms among people living with HIV and elevated depressive symptoms. We examined the association between patient engagement and depressive symptoms in the intervention group (n=150) where participants received an adapted cognitive-behavioral stress management (CBSM) course and physical activity promotion on their WeChat social media app. Depressive symptoms were repeatedly measured using the Patient Health Questionnaire (PHQ-9) at baseline and 1 month, 2 months, and 3 months. Patient engagement was correspondingly measured by the completion rate, frequency of items completed, and time spent on the program at 1 month, 2 months, and 3 months. Latent growth curve models (LGCMs) were used to explore the relationship between patient engagement and depressive symptoms at multiple time points in the intervention. Results The mean PHQ-9 scores were 10.2 (SD 4.5), 7.7 (SD 4.8), 6.5 (SD 4.7), and 6.7 (SD 4.1) at baseline, 1 month, 2 months, and 3 months, respectively. The mean completion rates were 50.6% (SD 31.8%), 51.5% (SD 32.2%), and 50.8% (SD 33.7%) at 1, 2, and 3 months, respectively; the average frequencies of items completed were 18.0 (SD 14.6), 32.6 (SD 24.8), and 47.5 (SD 37.2) at 1, 2, and 3 months, respectively, and the mean times spent on the program were 32.7 (SD 66.7), 65.4 (SD 120.8), and 96.4 (SD 180.4) minutes at 1, 2, and 3 months, respectively. LGCMs showed good model fit and indicated that a higher completion rate (β at 3 months=–2.184, P=.048) and a greater frequency of items completed (β at 3 months=–0.018, P=.04) were associated with fewer depressive symptoms at 3 months. Although not significant, similar trends were found in the abovementioned relationships at 1 and 2 months. There was no significant relationship between time spent on the program and depressive symptoms. Conclusions This study revealed a positive association between patient engagement and health outcomes at 3 months of an mHealth intervention using LGCMs and repeated measures data. The results underscore the importance of improving patient engagement in mHealth interventions to improve patient-centered health outcomes. Trial Registration Chinese Clinical Trial Registry ChiCTR-IPR-17012606; https://tinyurl.com/yxb64mef International Registered Report Identifier (IRRID) RR2-10.1186/s12889-018-5693-1


2020 ◽  
Author(s):  
Yu Zeng ◽  
Yan Guo ◽  
Linghua Li ◽  
Y Alicia Hong ◽  
Yiran Li ◽  
...  

BACKGROUND Associations between higher levels of patient engagement and better health outcomes have been found in face-to-face interventions; studies on such associations with mobile health (mHealth) interventions have been limited and the results are inconclusive. OBJECTIVE The objective of this study is to investigate the relationship between patient engagement in an mHealth intervention and depressive symptoms using repeated measures of both patient engagement and patient outcomes at 4 time points. METHODS Data were drawn from a randomized controlled trial (RCT) of an mHealth intervention aimed at reducing depressive symptoms among people living with HIV and elevated depressive symptoms. We examined the association between patient engagement and depressive symptoms in the intervention group (n=150) where participants received an adapted cognitive-behavioral stress management (CBSM) course and physical activity promotion on their WeChat social media app. Depressive symptoms were repeatedly measured using the Patient Health Questionnaire (PHQ-9) at baseline and 1 month, 2 months, and 3 months. Patient engagement was correspondingly measured by the completion rate, frequency of items completed, and time spent on the program at 1 month, 2 months, and 3 months. Latent growth curve models (LGCMs) were used to explore the relationship between patient engagement and depressive symptoms at multiple time points in the intervention. RESULTS The mean PHQ-9 scores were 10.2 (SD 4.5), 7.7 (SD 4.8), 6.5 (SD 4.7), and 6.7 (SD 4.1) at baseline, 1 month, 2 months, and 3 months, respectively. The mean completion rates were 50.6% (SD 31.8%), 51.5% (SD 32.2%), and 50.8% (SD 33.7%) at 1, 2, and 3 months, respectively; the average frequencies of items completed were 18.0 (SD 14.6), 32.6 (SD 24.8), and 47.5 (SD 37.2) at 1, 2, and 3 months, respectively, and the mean times spent on the program were 32.7 (SD 66.7), 65.4 (SD 120.8), and 96.4 (SD 180.4) minutes at 1, 2, and 3 months, respectively. LGCMs showed good model fit and indicated that a higher completion rate (β at 3 months=–2.184, <i>P</i>=.048) and a greater frequency of items completed (β at 3 months=–0.018, <i>P</i>=.04) were associated with fewer depressive symptoms at 3 months. Although not significant, similar trends were found in the abovementioned relationships at 1 and 2 months. There was no significant relationship between time spent on the program and depressive symptoms. CONCLUSIONS This study revealed a positive association between patient engagement and health outcomes at 3 months of an mHealth intervention using LGCMs and repeated measures data. The results underscore the importance of improving patient engagement in mHealth interventions to improve patient-centered health outcomes. CLINICALTRIAL Chinese Clinical Trial Registry ChiCTR-IPR-17012606; https://tinyurl.com/yxb64mef INTERNATIONAL REGISTERED REPORT RR2-10.1186/s12889-018-5693-1


2012 ◽  
Vol 26 (3) ◽  
pp. 182-204 ◽  
Author(s):  
Worawan White ◽  
Joan S. Grant ◽  
Erica R. Pryor ◽  
Norman L. Keltner ◽  
David E. Vance ◽  
...  

Social support, stigma, and social problem solving may be mediators of the relationship between sign and symptom severity and depressive symptoms in people living with HIV (PLWH). However, no published studies have examined these individual variables as mediators in PLWH. This cross-sectional, correlational study of 150 PLWH examined whether social support, stigma, and social problem solving were mediators of the relationship between HIV-related sign and symptom severity and depressive symptoms. Participants completed self-report questionnaires during their visits at two HIV outpatient clinics in the Southeastern United States. Using multiple regression analyses as a part of mediation testing, social support, stigma, and social problem solving were found to be partial mediators of the relationship between sign and symptom severity and depressive symptoms, considered individually and as a set.


2021 ◽  
Author(s):  
Angela M. Parcesepe ◽  
Molly Remch ◽  
Anastase Dzudie ◽  
Rogers Ajeh ◽  
Denis Nash ◽  
...  

2021 ◽  
pp. 1-26
Author(s):  
David A. Wiss ◽  
Marjan Javanbakht ◽  
Michael J. Li ◽  
Michael Prelip ◽  
Robert Bolan ◽  
...  

Abstract Objective: To understand the relationship between drug use, food insecurity (FI), and mental health among men who have sex with men (MSM). Design: Cohort study (2014-2019) with at least one follow-up. Setting: Visits at 6-month intervals included self-assessment for FI and depressive symptoms. Urine testing results confirmed drug use. Factors associated with FI were assessed using multiple logistic regression with random effects for repeated measures. General structural equation modeling tested whether FI mediates the relationship between drug use and depressive symptoms. Participants: Data were from HIV-positive and high-risk HIV negative MSM in Los Angeles, CA (n=431; 1,192 visits). Results: At baseline, FI was reported by 50.8% of participants, depressive symptoms in 36.7%, and 52.7% of urine screening tests were positive for drugs (i.e., marijuana, opioids, methamphetamine, cocaine, ecstasy). A positive drug test was associated with a 96% increase in the odds of being food insecure (95% CI: 1.26-3.07). Compared to those with high food security, individuals with very low food security have a nearly 7-fold increase in the odds of reporting depressive symptoms (95% CI: 3.71-11.92). Findings showed 14.9% of the association between drug use (exposure) and depressive symptoms (outcome) can be explained by FI (mediator). Conclusion: The prevalence of FI among this cohort of HIV-positive and high-risk HIV-negative MSM was high; the association between drug use and depressive symptoms was partially mediated by FI. Findings suggest that enhancing access to food and nutrition may improve mood in the context of drug use, especially among MSM at risk for HIV-transmission.


AIDS Care ◽  
2011 ◽  
Vol 23 (4) ◽  
pp. 426-434 ◽  
Author(s):  
Sandor Klis ◽  
Kristien Velding ◽  
Yori Gidron ◽  
Kevin Peterson

2016 ◽  
Vol 9 (1) ◽  
pp. 31999 ◽  
Author(s):  
Mayumi Shimizu ◽  
Siyan Yi ◽  
Sovannary Tuot ◽  
Samedy Suong ◽  
Samrithea Sron ◽  
...  

2011 ◽  
Vol 36 (5) ◽  
pp. 527-531 ◽  
Author(s):  
Diana Fishbein ◽  
Scott P. Novak ◽  
Christopher Krebs ◽  
Tara Warner ◽  
Jane Hammond

2015 ◽  
Vol 9 ◽  
pp. 64-75
Author(s):  
Md. Zawawi Abu Bakar ◽  
Rajwani Md. Zain ◽  
Wan Ab Rahman Khudzri Wan Abdullah

This paper aims to explain the dilemma that occurs in marital relationships. The issue of performing the external or internal maintenance obligation on the husband who has HIV / AIDS causes the wife to suffer. Thus, a qualitative study has been done to identify the dilemma that occurs in the relationship between husband and wife. Archival research methods such as the provisions of Islamic Family Law (UUKI), fiqh munakahat and case studies have been used. Interview methods were also performed to answer the objectives of the study. A total of 8 respondents, namely the wives of AIDS sufferers, were interviewed to obtain study data and the data was finally analyzed manually (QDA). The results show that there is discrimination against people living with HIV / AIDS (OHDHA) (wife) in the form of external and internal maintenance (husband and wife relationship). Even sadder, all respondents have been infected with HIV / AIDS as a result of intimate relationships with their husbands. The study finally concludes that OHDHA (wife) needs guidance and understanding of how to deal with the dilemma of performing duties as a wife and avoiding darar treatment from her partner (husband). Keywords: UUKI, Obligation, Wife, nafkah, HIV/AIDS. Makalah ini bertujuan menjelaskan dilema yang berlaku dalam hubungan suami isteri. Isu berkenaan melaksanakan kewajipan nafkah zahir atau batin terhadap suami yang menghidap HIV/AIDS menyebabkan isteri menderita. Justeru, satu kajian kualitatif telah dilakukan untuk mengenal pasti dilemma tersebut yang berlaku dalam hubungan suami isteri. Kaedah kajian arkib seperti peruntukan Undang-Undang Keluarga Islam (UUKI), fiqh munakahat dan kajian kes telah digunakan. Kaedah temubual juga telah dilakukan untuk menjawab objektif kajian. Responden seramai 8 orang iaitu isteri kepada penghidap AIDS telah ditemubual bagi mendapat data kajian dan data akhirnya dianalisis secara manual (QDA). Hasil kajian menunjukkan bahawa berlaku diskriminasi terhadap Orang Hidup Dengan HIV/AIDS (OHDHA) (isteri) iaitu dalam bentuk nafkah zahir dan batin (hubungan suami isteri). Lebih menyedihkan lagi semua responden telah dijangkiti HIV/AIDS hasil hubungan intim bersama suami. Kajian akhirnya menyimpulkan bahawa OHDHA (isteri) perlu kepada bimbingan dan pemahaman bagaimana menangani dilemma melaksanakan kewajipan sebagai isteri dan mengelakkan daripada perlakuan darar daripada pasangannya (suami).   Kata kunci: UUKI, kewajipan, isteri, nafkah, HIV/AIDS


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