Genetic and Environmental Influences on Semantic Verbal Fluency Across Midlife and Later Life

2021 ◽  
Author(s):  
Daniel E. Gustavson ◽  
◽  
Matthew S. Panizzon ◽  
William S. Kremen ◽  
Chandra A. Reynolds ◽  
...  
Keyword(s):  
Verbal Fluency ◽  
Environmental Influences ◽  
Later Life ◽  
Semantic Verbal Fluency

scholarly journals Genetic and environmental influences on semantic verbal fluency across midlife and later life

2020 ◽  
Vol 16 (S3) ◽  
Author(s):  
Daniel E. Gustavson ◽  
Matthew S. Panizzon ◽  
William S. Kremen ◽  
Chandra A. Reynolds ◽  
Marianne Nygaard ◽  
...  
Keyword(s):  
Verbal Fluency ◽  
Environmental Influences ◽  
Later Life ◽  
Semantic Verbal Fluency

scholarly journals Effects of Cancer, Chemotherapy and Cytokines on Subjective and Objective Cognitive Functioning Among Patients with Breast Cancer

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2576
Author(s):  
Vincent Chin-Hung Chen ◽  
Chin-Kuo Lin ◽  
Han-Pin Hsiao ◽  
Bor-Show Tzang ◽  
Yen-Hsuan Hsu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cognitive Function ◽  
Cognitive Abilities ◽  
Verbal Fluency ◽  
Control Group ◽  
Control Groups ◽  
Semantic Verbal Fluency ◽  
Cytokine Levels ◽  
Chemotherapy Patients ◽  
And Control

Background: We aimed to investigate the associations of breast cancer (BC) and cancer-related chemotherapies with cytokine levels, and cognitive function. Methods: We evaluated subjective and objective cognitive function in BC patients before chemotherapy and 3~9 months after the completion of chemotherapy. Healthy volunteers without cancer were also compared as control group. Interleukins (IL) 2, 4, 5, 6, 10, 12p70, 13, 17A, 1β, IFNγ, and TNFα were measured. Associations of cancer status, chemotherapy and cytokine levels with subjective and objective cognitive impairments were analyzed using a regression model, adjusting for covariates, including IQ and psychological distress. Results: After adjustment, poorer performance in semantic verbal fluency was found in the post-chemotherapy subgroup compared to controls (p = 0.011, η2 = 0.070); whereas pre-chemotherapy patients scored higher in subjective cognitive perception. Higher IL-13 was associated with lower semantic verbal fluency in the post-chemotherapy subgroup. Higher IL-10 was associated with better perceived cognitive abilities in the pre-chemotherapy and control groups; while IL-5 and IL-13 were associated with lower perceived cognitive abilities in pre-chemotherapy and control groups. Our findings from mediation analysis further suggest that verbal fluency might be affected by cancer status, although mediated by anxiety. Conclusions: Our findings suggest that verbal fluency might be affected by cancer status, although mediated by anxiety. Different cytokines and their interactions may have different roles of neuroinflammation or neuroprotection that need further research.

Patients with amnestic MCI Fail to Adapt Executive Control When Repeatedly Tested with Semantic Verbal Fluency Tasks

2021 ◽  
pp. 1-8
Author(s):  
Johannes Tröger ◽  
Hali Lindsay ◽  
Mario Mina ◽  
Nicklas Linz ◽  
Stefan Klöppel ◽  
...  
Keyword(s):  
Executive Control ◽  
Verbal Fluency ◽  
Fixed Time ◽  
Semantic Space ◽  
Semantic Knowledge ◽  
Semantic Verbal Fluency ◽  
Amnestic Mci ◽  
Retrieval Processes ◽  
Theoretical View ◽  
First Time

Abstract Objective: Semantic verbal fluency (SVF) tasks require individuals to name items from a specified category within a fixed time. An impaired SVF performance is well documented in patients with amnestic Mild Cognitive Impairment (aMCI). The two leading theoretical views suggest either loss of semantic knowledge or impaired executive control to be responsible. Method: We assessed SVF 3 times on 2 consecutive days in 29 healthy controls (HC) and 29 patients with aMCI with the aim to answer the question which of the two views holds true. Results: When doing the task for the first time, patients with aMCI produced fewer and more common words with a shorter mean response latency. When tested repeatedly, only healthy volunteers increased performance. Likewise, only the performance of HC indicated two distinct retrieval processes: a prompt retrieval of readily available items at the beginning of the task and an active search through semantic space towards the end. With repeated assessment, the pool of readily available items became larger in HC, but not patients with aMCI. Conclusion: The production of fewer and more common words in aMCI points to a smaller search set and supports the loss of semantic knowledge view. The failure to improve performance as well as the lack of distinct retrieval processes point to an additional impairment in executive control. Our data did not clearly favour one theoretical view over the other, but rather indicates that the impairment of patients with aMCI in SVF is due to a combination of both.

scholarly journals Quantitative and qualitative analysis of semantic verbal fluency in patients with temporal lobe epilepsy

2020 ◽  
Vol 35 (1) ◽  
pp. 1-9
Author(s):  
A.G. Jaimes-Bautista ◽  
M. Rodríguez-Camacho ◽  
I.E. Martínez-Juárez ◽  
Y. Rodríguez-Agudelo
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Qualitative Analysis ◽  
Temporal Lobe ◽  
Verbal Fluency ◽  
Semantic Verbal Fluency

scholarly journals Performance of Children in Phonemic and Semantic Verbal Fluency Tasks

Psico-USF ◽  
2016 ◽  
Vol 21 (2) ◽  
pp. 293-304 ◽  
Author(s):  
Gilmara de Lucena Leite ◽  
Izabel Augusta Hazin Pires ◽  
Laura Carolina Lemos Aragão ◽  
Artemis Paiva de Paula ◽  
Ediana Rossely de Oliveira Gomes ◽  
...  
Keyword(s):  
Explicit Memory ◽  
Verbal Fluency ◽  
Age Groups ◽  
Memory Systems ◽  
Semantic Fluency ◽  
Age And Gender ◽  
Northeast Region ◽  
Semantic Verbal Fluency ◽  
And Gender ◽  
Brazilian Northeast

Abstract This study investigated the performance of children from the Brazilian Northeast region, from 7 to 10 years in phonemic and semantic verbal fluency tasks. The participants were 102 subjects (62 girls and 40 boys) who performed three phonemic and three semantic fluency tasks. The results were submitted to correlational and variance analysis to investigate the influence of the variables age and gender on the subjects performance. There was no effect of gender on the results. Significant contrasts between age groups were found, and better performance was observed on phonemic tasks. Also, the performance in this task changed along development, in contrast to what happened with the semantic fluency. The findings seem to be in accordance to neurodevelopmental aspects, taken into account that explicit memory systems show more precocious maturational course, with earlier consolidation, in comparison to the executive functions and frontal lobes, which go on developing until adult ages.

scholarly journals Heritability of an Age-Dependent Categorical Phenotype: Cognitive Dysfunction

2006 ◽  
Vol 9 (1) ◽  
pp. 17-23 ◽  
Author(s):  
Chandra A. Reynolds ◽  
Amy Fiske ◽  
Laura Fratiglioni ◽  
Nancy L. Pedersen ◽  
Margaret Gatz
Keyword(s):  
Cognitive Dysfunction ◽  
Ordinal Data ◽  
Rating Scale ◽  
Environmental Influences ◽  
Later Life ◽  
Relative Magnitude ◽  
Assessment Instrument ◽  
Best Fitting ◽  
Brief Cognitive Assessment ◽  
Cognitively Intact

AbstractWe investigated the extent to which cognitive dysfunction is shaped by genetic or environmental influences, and whether these factors differ in women and men. All members of the Swedish Twin Registry aged 65 and older were screened by telephone using the TELE, a brief cognitive assessment instrument (Gatz et al., 2002), and the Blessed Dementia Rating Scale (Blessed et al., 1968) from relatives of those who scored poorly on the TELE. Data were available for 4308 pairs where both members responded and 5070 pairs where only one member was alive and participated. To analyze all available data, we used a raw data method extended to ordinal data. As the prevalence of cognitive dysfunction increases with age, we incorporated age-adjusted thresholds. The best fitting model from biometric analyses indicated 35% of the variation in liability to cognitive dysfunction could be explained by heritable influences and the remaining 65% by nonfamilial environmental influences. Differences by gender were not significant. As this is a normative population including cognitively intact individuals, preclinical dementia cases and demented individuals, the relative magnitude of genetic and environmental effects is of particular interest in light of high heritabilities found for dementias such as Alzheimer's disease. The findings emphasize the extent to which research is needed to uncover nonfamilial environmental influences on cognitive dysfunction in later life.

Semantic Verbal Fluency Measure

2012 ◽  
Author(s):  
Luna Beck ◽  
Irina R. Kumschick ◽  
Michael Eid ◽  
Gisela Klann-Delius
Keyword(s):  
Verbal Fluency ◽  
Semantic Verbal Fluency

scholarly journals Longitudinal studies of cognition in schizophrenia: Meta-analysis

2008 ◽  
Vol 192 (4) ◽  
pp. 248-257 ◽  
Author(s):  
Andrei Szöke ◽  
Anca Trandafir ◽  
Marie-Estelle Dupont ◽  
Alexandre Méary ◽  
Franck Schürhoff ◽  
...  
Keyword(s):  
Longitudinal Studies ◽  
Cognitive Deficits ◽  
Verbal Fluency ◽  
Meta Analysis ◽  
Cognitive Remediation ◽  
Cognitive Tasks ◽  
Longitudinal Course ◽  
Semantic Verbal Fluency ◽  
Wide Range ◽  
Available Information

BackgroundA wide range of cognitive deficits have been demonstrated in schizophrenia, but their longitudinal course remains unclear.AimsTo bring together all the available information from longitudinal studies of cognitive performance in people with schizophrenia.MethodWe carried out a meta-analysis of 53 studies. Unlike previous reviewers, we included all studies (regardless of the type of medication), analysed each variable separately and compared results with data from controls.ResultsParticipants with schizophrenia showed a significant improvement in most cognitive tasks. The available data for controls showed, with one exception (the Stroop test), a similar or greater improvement. Performance in semantic verbal fluency remained stable in both individuals with schizophrenia and controls.ConclusionsParticipants with schizophrenia displayed improvement in most cognitive tasks, but practice was more likely than cognitive remediation to account for most of the improvements observed. Semantic verbal fluency may be the best candidate cognitive endophenotype.

Sign in / Sign up

Export Citation Format

Share Document