New Triterpenoid Saponin C-20 Epimers from the Alkaline-Degradation Products of Ginsenoside Re and Their Cytotoxic Activities

2018 ◽  
Vol 54 (3) ◽  
pp. 490-495
Author(s):  
Hongda Ding ◽  
Zhicai Wang ◽  
Xia Chen ◽  
Pengfei Zhang ◽  
Fangfei Xu ◽  
...  
Keyword(s):  
Degradation Products ◽  
Cytotoxic Activities ◽  
Triterpenoid Saponin ◽  
Alkaline Degradation ◽  
Ginsenoside Re

scholarly journals Bunias erucago L.: Glucosinolate Profile and In Vitro Biological Potential

Molecules ◽  
2019 ◽  
Vol 24 (4) ◽  
pp. 741 ◽  
Author(s):  
Ivica Blažević ◽  
Azra Đulović ◽  
Vedrana Čikeš Čulić ◽  
Franko Burčul ◽  
Ivica Ljubenkov ◽  
...  
Keyword(s):  
Degradation Products ◽  
Dry Weight ◽  
Mediterranean Area ◽  
Biological Properties ◽  
Glucosinolate Content ◽  
Cytotoxic Activities ◽  
Plant Parts ◽  
Biological Potential ◽  
Glucosinolate Profile

Bunias erucago belongs to the Brassicaceae family, which represents a forgotten crop of the Euro-Mediterranean area. The aim of the present study was to determine the glucosinolate profile in different plant parts and biological properties (antioxidant, anticholinesterase, and cytotoxic activities) of the isolates containing glucosinolate breakdown products. The chemical profiles were determined by using HPLC-PDA-MS/MS of desulfoglucosinolates and GC-MS of glucosinolate degradation products. The analysis of B. erucago showed the presence of seven glucosinolates: gluconapin (1), glucoraphasatin (2), glucoraphenin (3), glucoerucin (4), glucoraphanin (5), glucotropaeolin (6), and glucosinalbin (7). The total glucosinolate content ranged from 7.0 to 14.6 µmol/g of dry weight, with the major glucosinolate glucosinalbin in all parts. The antioxidant activity of all volatile isolates was not notable. At a tested concentration of 227 μg/mL, flower hydro-distillate (FH) showed good AChE inhibition, i.e., 40.9%, while root hydro-distillate (RH) had good activity against BChE, i.e., 54.3%. FH showed the best activity against both tested human bladder cancer cell lines, i.e., against T24 after 72 h, which have IC50 of 16.0 μg/mL, and against TCCSUP after 48 h with IC50 of 7.8 μg/mL, and can be considered as highly active. On the other hand, RH showed weak activity against tested cancer cells.

Polysaccharide alkaline degradation products as a source of organic chemicals

1984 ◽  
Vol 23 (1) ◽  
pp. 70-73 ◽  
Author(s):  
Marten Reintjes ◽  
Geoffrey K. Cooper
Keyword(s):  
Degradation Products ◽  
Organic Chemicals ◽  
Alkaline Degradation

Some properties of tobacco etch virus and its alkaline degradation products

Virology ◽  
1966 ◽  
Vol 29 (1) ◽  
pp. 8-14 ◽  
Author(s):  
D.E. Purcifull
Keyword(s):  
Degradation Products ◽  
Tobacco Etch Virus ◽  
Alkaline Degradation

Micelle-enhanced spectrofluorimetric method for determination of sitagliptin and identification of potential alkaline degradation products using LC-MS

Luminescence ◽  
2013 ◽  
Vol 29 (1) ◽  
pp. 65-73 ◽  
Author(s):  
MM Salim ◽  
N El-Enany ◽  
F Belal ◽  
MI Walash ◽  
G Patonay
Keyword(s):  
Degradation Products ◽  
Alkaline Degradation ◽  
Spectrofluorimetric Method

Kinetic study of the alkaline degradation of imidapril hydrochloride using a validated stability indicating HPLC method

RSC Advances ◽  
2016 ◽  
Vol 6 (73) ◽  
pp. 69239-69250
Author(s):  
Shabaan A. Abdulla ◽  
Eman Y. Frag ◽  
Heba E. Ahmed
Keyword(s):  
Kinetic Study ◽  
Degradation Products ◽  
Hplc Method ◽  
Alkaline Degradation ◽  
Degradation Study ◽  
Stability Indicating ◽  
Stability Indicating Method ◽  
Imidapril Hydrochloride

An aqueous alkaline degradation study was performed for imidapril hydrochloride (IMD) drug in the presence of its degradation products and an isocratic stability indicating method was presented using HPLC.

Linkage analysis of oligosaccharides by thin-layer chromatography of their alkaline-degradation products

1968 ◽  
Vol 6 (3) ◽  
pp. 341-346 ◽  
Author(s):  
S.A. Barker ◽  
J.M. Edwards ◽  
P.J. Somers ◽  
A. Repǎs
Keyword(s):  
Linkage Analysis ◽  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Degradation Products ◽  
Alkaline Degradation ◽  
Layer Chromatography
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