scholarly journals Hesitant but vaccinated: assessing COVID-19 vaccine hesitancy among the recently vaccinated

2022 ◽  
Author(s):  
Don E. Willis ◽  
James P. Selig ◽  
Jennifer A. Andersen ◽  
Spencer Hall ◽  
Emily Hallgren ◽  
...  
Keyword(s):  
Vaccine Hesitancy

Sharp rise in vaccine hesitancy in a large and representative sample of the French population: reasons for vaccine hesitancy.

2020 ◽  
Author(s):  
Anne-Sophie Hacquin ◽  
Sacha Altay ◽  
Emma de Araujo ◽  
Coralie Chevallier ◽  
Hugo Mercier
Keyword(s):  
At Risk ◽  
Educational Level ◽  
Representative Sample ◽  
Vaccine Hesitancy ◽  
The Political ◽  
French Population ◽  
Sharp Rise ◽  
Vaccine Refusal ◽  
French People ◽  
Nationally Representative

A safe and effective COVID-19 vaccine is our only hope to decisively stop the spread of the SARS-CoV-2. But a vaccine will only be fully effective if a significant share of the population agrees to get it. Five consecutive surveys of a large, nationally representative sample (N = 1000 for each wave) surveyed attitudes towards a future COVID-19 vaccine in France from May 2020 to October 2020. We found that COVID-19 vaccine refusal has steadily increased, reaching an all-time high with only 23% of participants willing to probably or certainly take a future COVID-19 vaccine in September 2020. Vaccine hesitant individuals are more likely to be women, young, less educated, to vote at the political extremes, to be dissatisfied with the government’s response to the COVID-19 crisis, and to feel less at risk of COVID-19. The reasons why French people would refuse to take the COVID-19 vaccine are similar to those offered for other vaccines, and these reasons are strikingly stable across gender, age and educational level. Finally, most French people declare they would not take the vaccine as soon as possible but would instead rather wait or not take it at all.

COVID-19 Vaccine Hesitancy in the French Population of Working Age: A Randomized Experiment of Vaccine Characteristics

2020 ◽  
Author(s):  
Michaël Schwarzinger ◽  
Verity Watson ◽  
Pierre Arwidson ◽  
François Alla ◽  
Stéphane Luchini
Keyword(s):  
Vaccine Hesitancy ◽  
Randomized Experiment ◽  
French Population ◽  
Working Age

Qualitative Analysis of Underlying Factors Affecting Vaccine Hesitancy in Iran- A Study Protocol (Preprint)

2020 ◽  
Author(s):  
Salime Goharinezhad
Keyword(s):  
Vaccine Coverage ◽  
Deep Understanding ◽  
World Health ◽  
Vaccine Hesitancy ◽  
Slight Reduction ◽  
Cultural Variation ◽  
Global Public Health ◽  
Factors Affecting ◽  
Wide Range ◽  
Context Specific

BACKGROUND World Health Organization declared the vaccine hesitancy as a global public health threat in 2019. Since even a slight reduction in vaccine coverage rates can lead to a decrease in herd immunity, it is imperative to explore the underlying factors affecting vaccine hesitancy. in specific contexts, considering socioeconomic and cultural variation, to ensure interventions targeting hesitancy are well formulated and intervened. OBJECTIVE The main objective of this study is to identify underlying factors affecting vaccine hesitancy in Iran. METHODS A framework qualitative study will be conducted in the west of Tehran province in 2020. Participants in the study will be recruited hesitance-parents who extracted from the SIB system (an electronic health record in Iran) to maximize diversity. Interviews will be analyzed based on ''Determinants of Vaccine Hesitancy Matrix'' which developed by the WHO-SAGE Working Group. RESULTS deep understanding from the context-specific reasons for vaccine hesitancy cause to formulate better strategies to address them. The ultimate goal of this study is to inform future policies to increase the uptake of the vaccine in Iran. CONCLUSIONS This result of study will show variety opinions about vaccination among different types of socioeconomic and demographic households. The wide range of reasons related to vaccine hesitancy imply to more comprehensive, context-specific interventions. Today, the most important intervention issues focus on improving information about effectiveness and safety of vaccines, while other interventions for promoting vaccination is need to addressed.

scholarly journals SARS-CoV-2: Vaccine Hesitancy among Underrepresented Racial and Ethnic Groups with HIV in Miami, Florida

2021 ◽  
Author(s):  
Deborah L Jones ◽  
Ana S Salazar ◽  
Violeta J Rodriguez ◽  
Raymond R Balise ◽  
Claudia Uribe Starita ◽  
...  
Keyword(s):  
Race And Ethnicity ◽  
Cross Sectional Study ◽  
Vaccine Uptake ◽  
Vaccine Hesitancy ◽  
Baseline Survey ◽  
Advisory Group ◽  
Medical Mistrust ◽  
Cross Sectional ◽  
Exact Test ◽  
Novel Coronavirus

Abstract Background SARS-CoV-2 and HIV disproportionally affect underrepresented ethnoracial groups in the US. Medical mistrust and vaccine hesitancy will likely impact acceptability of SARS-CoV-2 vaccines. This study examined SARS-CoV-2 vaccine hesitancy among underrepresented ethnoracial groups with HIV and identified factors that may reduce vaccine uptake. Methods We conducted a cross-sectional study of adults ≥18 years with HIV residing in Miami, FL. Participants were invited to participate in the ACTION (A Comprehensive Translational Initiative on Novel Coronavirus) cohort study. A baseline survey was administered from April-August 2020 and followed by a COVID-19 vaccine hesitancy survey from August-November 2020. The COVID-19 vaccine hesitancy survey was adapted from the Strategic Advisory Group Experts survey. Comparisons by race and ethnicity were performed using the Freedman-Haltmann extension of Fisher’s exact test Results A total of 94 participants were enrolled, mean age 54.4 years, 52% female, 60% Black non-Latinx, and 40% non-Black Latinx. Black non-Latinx participants were less likely to agree that vaccinations are important for health when compared to non-Black Latinx (67.8% vs 92.1%, p=0.009), less likely to agree that vaccines are effective in preventing disease (67.8% vs 84.2%, p=0.029), less likely to believe that vaccine information is reliable and trustworthy (35.7% vs 71.1%, p=0.002), and less likely to believe vaccines were unnecessary because COVID-19 would disappear soon (11% vs 21%, p=0.049). Conclusion Medical mistrust, vaccine hesitancy and negative sentiments about SARS-CoV-2 vaccines are prevalent among underrepresented ethnoracial groups with HIV, particularly Black non-Latinx. Targeted strategies to increase vaccine uptake in this population are warranted.

scholarly journals Can shared decision making address COVID-19 vaccine hesitancy?

2021 ◽  
pp. bmjebm-2021-111695
Author(s):  
Marie-Anne Durand ◽  
Peter Scalia ◽  
Glyn Elwyn
Keyword(s):  
Decision Making ◽  
Shared Decision Making ◽  
Vaccine Hesitancy ◽  
Shared Decision

scholarly journals COVID-19 Vaccine Rollout: will it affect the Rates of Vaccine Hesitancy in Africa?

Public Health ◽  
2021 ◽  
Author(s):  
Osmond C. Ekwebelem ◽  
Ismaeel Yunusa ◽  
Helen Onyeaka ◽  
Nicholas C. Ekwebelem ◽  
Obinna Nnorom-Dike
Keyword(s):  
Vaccine Hesitancy

scholarly journals Thrombotic Thrombocytopenia after COVID-19 Vaccination: In Search of the Underlying Mechanism

Vaccines ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 559
Author(s):  
Piotr Rzymski ◽  
Bartłomiej Perek ◽  
Robert Flisiak
Keyword(s):  
Direct Interaction ◽  
Underlying Mechanism ◽  
The United States ◽  
Cross Reactivity ◽  
Spike Protein ◽  
Vaccine Hesitancy ◽  
Future Research ◽  
Platelet Factor ◽  
Precautionary Measures ◽  
Adenoviral Proteins

The rollout of COVID-19 vaccines brings hope for successful pandemic mitigation and getting the transmission of SARS-CoV-2 under control. The vaccines authorized in Europe displayed a good safety profile in the clinical trials. However, during their post-authorization use, unusual thrombotic events associated with thrombocytopenia have rarely been reported for vector vaccines. This led to the temporary suspension of the AZD1222 vaccine (Oxford/AstraZeneca) in various European countries and the Ad26.COV2 vaccine (Janssen/Johnson&Johnson) in the United States, with regulatory bodies launching investigations into potential causal associations. The thromboembolic reactions were also rarely reported after mRNA vaccines. The exact cause of these adverse effects remains to be elucidated. The present paper outlines the hypotheses on the mechanisms behind the very rare thrombotic thrombocytopenia reported after the COVID-19 vaccination, along with currently existing evidence and future research prospects. The following are discussed: (i) the role of antibodies against platelet factor 4 (PF4), (ii) the direct interaction between adenoviral vector and platelets, (iii) the cross-reactivity of antibodies against SARS-CoV-2 spike protein with PF4, (iv) cross-reactivity of anti-adenovirus antibodies and PF4, (v) interaction between spike protein and platelets, (vi) the platelet expression of spike protein and subsequent immune response, and (vii) the platelet expression of other adenoviral proteins and subsequent reactions. It is also plausible that thrombotic thrombocytopenia after the COVID-19 vaccine is multifactorial. The elucidation of the causes of these adverse events is pivotal in taking precautionary measures and managing vaccine hesitancy. It needs to be stressed, however, that the reported cases are currently sporadic and that the benefits of COVID-19 vaccines vastly outweigh their potential risks.

scholarly journals The Limits of Medical Trust in Mitigating COVID-19 Vaccine Hesitancy among Black Americans

2021 ◽  
Author(s):  
Justin Stoler ◽  
Adam M. Enders ◽  
Casey A. Klofstad ◽  
Joseph E. Uscinski
Keyword(s):  
Black Americans ◽  
Vaccine Hesitancy

scholarly journals Promoting COVID-19 vaccination among healthcare personnel: a multifaceted intervention at a tertiary care center in Japan

2021 ◽  
pp. 1-26
Author(s):  
Akane Takamatsu ◽  
Hitoshi Honda ◽  
Tomoya Kojima ◽  
Kengo Murata ◽  
Hilary Babcock
Keyword(s):  
Medical Center ◽  
Care Center ◽  
Tertiary Care ◽  
Vaccination Rate ◽  
Multifaceted Intervention ◽  
Vaccine Hesitancy ◽  
Healthcare Personnel ◽  
Tertiary Care Center ◽  
Post Intervention ◽  
Post Vaccination

Abstract Objective The COVID-19 vaccine may hold the key to ending the pandemic, but vaccine hesitancy is hindering the vaccination of healthcare personnel (HCP). Design Before-after trial Participants and setting Healthcare personnel at a 790-bed tertiary care center in Tokyo, Japan. Interventions A pre-vaccination questionnaire was administered to HCP to examine their perceptions of the COVID-19 vaccine. Then, a multifaceted intervention involving (1) distribution of informational leaflets to all HCP, (2) hospital-wide announcements encouraging vaccination, (3) a mandatory lecture, (4) an educational session about the vaccine for pregnant or breastfeeding HCP, and (5) allergy testing for HCP at risk of allergic reactions to the vaccine was implemented. A post-vaccination survey was also performed. Results Of 1,575 HCP eligible for enrollment, 1,224 (77.7%) responded to the questionnaire, 43.5% (n =533) expressed willingness to be vaccinated, 48.4% (n = 593) were uncertain, and 8.0% (n=98) expressed unwillingness to be vaccinated. The latter two groups were concerned about the vaccine’s safety rather than its efficacy. Post-intervention, the overall vaccination rate reached 89.7% (1,413/1,575), with 88.9% (614/691) of the pre-vaccination survey respondents who answered “unwilling” or “unsure” eventually receiving a vaccination. In the post-vaccination questionnaire, factors contributing to increased COVID-19 vaccination included information and endorsement of vaccination at the medical center (26.4%; 274/1,037). Conclusions The present, multifaceted intervention increased COVID-19 vaccinations among HCP at a Japanese hospital. Frequent support and provision of information were crucial for increasing the vaccination rate and may be applicable to the general population as well.

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