scholarly journals “Life is at a standstill” Quality of life after lower extremity trauma in Malawi

2016 ◽  
Vol 26 (4) ◽  
pp. 1027-1035 ◽  
Author(s):  
Racquel E. Kohler ◽  
Jared Tomlinson ◽  
Tiyamike Eletima Chilunjika ◽  
Sven Young ◽  
Mina Hosseinipour ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lower Extremity ◽  
Lower Extremity Trauma ◽  
Extremity Trauma

scholarly journals Patient Reported Outcomes after Local Flap Coverage for Lower Extremity Trauma

2020 ◽  
Vol 3 ◽  
Author(s):  
Neel Bhagat ◽  
Scott Loewenstein ◽  
Kevin Knox ◽  
Joshua Adkinson ◽  
Aladdin Hassanein ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lower Extremity ◽  
Local Flaps ◽  
Fasciocutaneous Flaps ◽  
Muscle Flaps ◽  
Lower Extremity Trauma ◽  
Sf 36 ◽  
Extremity Trauma ◽  
Patient Reported

Background:  Complex lower extremity trauma can result in devastating outcomes including amputation and poor quality of life. Limb salvage can be achieved with the use of local flaps like muscle flaps such as the gastrocnemius or soleus flaps, which detach muscles in order to use them for local coverage.  Fasciocutaneous flaps such as reverse sural and propeller flaps are other examples of local flaps which utilize overlying soft tissue for local rearrangement.  Patient-reported outcome (PRO) studies have not been reported for local flaps. Additionally, the potential for functional deficits as a result of muscle flaps in comparison to fasciocutaneous flaps has not been investigated.    Methods:  Local flap coverage for lower extremity traumas between 2014-2019 were reviewed. 248 local flaps were performed for lower extremity salvage following trauma. PROs were recorded utilizing both the Lower Extremity Functional scale (LEFS) and the 36-Item Short-Form Health Survey (SF-36).     Results:  Surveys were completed by 37 patients (response rate 18.3%, mean follow-up time 3.16 years, average age 49.72 years old). The average LEFS score was 42.09 ± 14.18, and the average physical functioning score was 43.03 ± 21.54. LEFS score and SF-36 physical functioning scores were significantly lower in patients who underwent muscle flaps compared to fasciocutaneous flaps (p=0.021 and p=0.022 respectively).    Conclusions and Impact:  Patients undergoing local flaps for lower extremity reconstruction have low quality of life scores. Patients who underwent fasciocutaneous flaps had significantly higher quality of life scores compared to muscle flap patients suggesting that fasciocutaneous flaps may cause less functional deficit in salvage operations. 

The Insensate Foot Following Severe Lower Extremity Trauma: An Indication for Amputation?

2006 ◽  
Vol 2006 ◽  
pp. 95-97
Author(s):  
M.F. Swiontkowski
Keyword(s):  
Lower Extremity ◽  
Lower Extremity Trauma ◽  
Extremity Trauma

scholarly journals Molecular Mechanisms Associated with ROS-Dependent Angiogenesis in Lower Extremity Artery Disease

Antioxidants ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 735
Author(s):  
Greg Hutchings ◽  
Łukasz Kruszyna ◽  
Mariusz J. Nawrocki ◽  
Ewa Strauss ◽  
Rut Bryl ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Blood Vessel ◽  
Lower Extremity ◽  
Molecular Mechanisms ◽  
Lower Extremities ◽  
Tissue Response ◽  
Peripheral Arteries ◽  
Artery Disease ◽  
Lower Extremity Artery Disease

Currently, atherosclerosis, which affects the vascular bed of all vital organs and tissues, is considered as a leading cause of death. Most commonly, atherosclerosis involves coronary and peripheral arteries, which results in acute (e.g., myocardial infarction, lower extremities ischemia) or chronic (persistent ischemia leading to severe heart failure) consequences. All of them have a marked unfavorable impact on the quality of life and are associated with increased mortality and morbidity in human populations. Lower extremity artery disease (LEAD, also defined as peripheral artery disease, PAD) refers to atherosclerotic occlusive disease of the lower extremities, where partial or complete obstruction of peripheral arteries is observed. Decreased perfusion can result in ischemic pain, non-healing wounds, and ischemic ulcers, and significantly reduce the quality of life. However, the progressive atherosclerotic changes cause stimulation of tissue response processes, like vessel wall remodeling and neovascularization. These mechanisms of adapting the vascular network to pathological conditions seem to play a key role in reducing the impact of the changes limiting the flow of blood. Neovascularization as a response to ischemia induces sprouting and expansion of the endothelium to repair and grow the vessels of the circulatory system. Neovascularization consists of three different biological processes: vasculogenesis, angiogenesis, and arteriogenesis. Both molecular and environmental factors that may affect the process of development and growth of blood vessels were analyzed. Particular attention was paid to the changes taking place during LEAD. It is important to consider the molecular mechanisms underpinning vessel growth. These mechanisms will also be examined in the context of diseases commonly affecting blood vessel function, or those treatable in part by manipulation of angiogenesis. Furthermore, it may be possible to induce the process of blood vessel development and growth to treat peripheral vascular disease and wound healing. Reactive oxygen species (ROS) play an important role in regulation of essential cellular signaling pathways such as cell differentiation, proliferation, migration and apoptosis. With regard to the repair processes taking place during diseases such as LEAD, prospective therapeutic methods have been described that could significantly improve the treatment of vessel diseases in the future. Summarizing, regenerative medicine holds the potential to transform the therapeutic methods in heart and vessel diseases treatment.

scholarly journals Risk Factor, Job Stress and Quality of Life in Workers With Lower Extremity Pain Who Use Video Display Terminals

2018 ◽  
Vol 42 (1) ◽  
pp. 101 ◽  
Author(s):  
Sehoon Choi ◽  
Seong Ho Jang ◽  
Kyu Hoon Lee ◽  
Mi Jung Kim ◽  
Si-Bog Park ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factor ◽  
Lower Extremity ◽  
Job Stress ◽  
Video Display ◽  
Video Display Terminals ◽  
Lower Extremity Pain

scholarly journals Lower extremity muscle strength is reduced in people with type 2 diabetes, with and without polyneuropathy, and is associated with impaired mobility and reduced quality of life

2012 ◽  
Vol 95 (3) ◽  
pp. 345-351 ◽  
Author(s):  
T. Herman IJzerman ◽  
Nicolaas C. Schaper ◽  
Tom. Melai ◽  
Kenneth Meijer ◽  
Paul J.B. Willems ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Type 2 Diabetes ◽  
Muscle Strength ◽  
Lower Extremity ◽  
Impaired Mobility ◽  
Lower Extremity Muscle

MULTIPLE RELAXING SKIN INCISIONS IN ORTHOPEDIC LOWER EXTREMITY TRAUMA

1991 ◽  
Vol 84 (Supplement) ◽  
pp. 60
Author(s):  
Anthony J. DiStasio ◽  
Thomas W. Dugdale ◽  
Martin K. Deafenbaugh
Keyword(s):  
Lower Extremity ◽  
Lower Extremity Trauma ◽  
Extremity Trauma

Common characteristics of functional and adverse outcomes in acute lower-extremity trauma reconstruction

2017 ◽  
Vol 40 (3) ◽  
pp. 235-244 ◽  
Author(s):  
Iris A. Seitz ◽  
Justine C. Lee ◽  
Suela Sulo ◽  
Varun Shah ◽  
Manoj Shah ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Adverse Outcomes ◽  
Lower Extremity Trauma ◽  
Extremity Trauma

scholarly journals Health-Related Quality of Life after Major Lower Extremity Amputation Due to Musculoskeletal Tumors

2017 ◽  
Vol 20 (9) ◽  
pp. A453-A454
Author(s):  
JP Repo ◽  
I Barner-Rasmussen ◽  
RP Roine ◽  
A Häkkinen ◽  
C Blomqvist ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lower Extremity ◽  
Lower Extremity Amputation ◽  
Health Related Quality ◽  
Musculoskeletal Tumors ◽  
Related Quality ◽  
Health Related ◽  
Extremity Amputation
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