scholarly journals Risk Factor, Job Stress and Quality of Life in Workers With Lower Extremity Pain Who Use Video Display Terminals

2018 ◽  
Vol 42 (1) ◽  
pp. 101 ◽  
Author(s):  
Sehoon Choi ◽  
Seong Ho Jang ◽  
Kyu Hoon Lee ◽  
Mi Jung Kim ◽  
Si-Bog Park ◽  
...  
Author(s):  
Eun Sook Jeon ◽  
Kang Sook Lee ◽  
Seon Young Lee ◽  
Jae Hee Yu ◽  
A Rum Hong

Antioxidants ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 735
Author(s):  
Greg Hutchings ◽  
Łukasz Kruszyna ◽  
Mariusz J. Nawrocki ◽  
Ewa Strauss ◽  
Rut Bryl ◽  
...  

Currently, atherosclerosis, which affects the vascular bed of all vital organs and tissues, is considered as a leading cause of death. Most commonly, atherosclerosis involves coronary and peripheral arteries, which results in acute (e.g., myocardial infarction, lower extremities ischemia) or chronic (persistent ischemia leading to severe heart failure) consequences. All of them have a marked unfavorable impact on the quality of life and are associated with increased mortality and morbidity in human populations. Lower extremity artery disease (LEAD, also defined as peripheral artery disease, PAD) refers to atherosclerotic occlusive disease of the lower extremities, where partial or complete obstruction of peripheral arteries is observed. Decreased perfusion can result in ischemic pain, non-healing wounds, and ischemic ulcers, and significantly reduce the quality of life. However, the progressive atherosclerotic changes cause stimulation of tissue response processes, like vessel wall remodeling and neovascularization. These mechanisms of adapting the vascular network to pathological conditions seem to play a key role in reducing the impact of the changes limiting the flow of blood. Neovascularization as a response to ischemia induces sprouting and expansion of the endothelium to repair and grow the vessels of the circulatory system. Neovascularization consists of three different biological processes: vasculogenesis, angiogenesis, and arteriogenesis. Both molecular and environmental factors that may affect the process of development and growth of blood vessels were analyzed. Particular attention was paid to the changes taking place during LEAD. It is important to consider the molecular mechanisms underpinning vessel growth. These mechanisms will also be examined in the context of diseases commonly affecting blood vessel function, or those treatable in part by manipulation of angiogenesis. Furthermore, it may be possible to induce the process of blood vessel development and growth to treat peripheral vascular disease and wound healing. Reactive oxygen species (ROS) play an important role in regulation of essential cellular signaling pathways such as cell differentiation, proliferation, migration and apoptosis. With regard to the repair processes taking place during diseases such as LEAD, prospective therapeutic methods have been described that could significantly improve the treatment of vessel diseases in the future. Summarizing, regenerative medicine holds the potential to transform the therapeutic methods in heart and vessel diseases treatment.


2016 ◽  
Vol 59 ◽  
pp. e76
Author(s):  
Ngor Side Diagne ◽  
Massaman Camara ◽  
Abou Sy ◽  
Ousmane Cissé ◽  
Amadou Koura Ndao ◽  
...  

2015 ◽  
Vol 24 (4) ◽  
pp. 372-380 ◽  
Author(s):  
Yunyoung Kim ◽  
Hye-Sun Hyun ◽  
Jong Hyang Yoo

2017 ◽  
Vol 100 ◽  
pp. 46-56 ◽  
Author(s):  
Tapas K. Ray ◽  
Tat'Yana A. Kenigsberg ◽  
Regina Pana-Cryan

2017 ◽  
Vol 20 (9) ◽  
pp. A453-A454
Author(s):  
JP Repo ◽  
I Barner-Rasmussen ◽  
RP Roine ◽  
A Häkkinen ◽  
C Blomqvist ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document