Antifungal activity of xenocoumacin 1 from Xenorhabdus nematophilus var. pekingensis against Phytophthora infestans

An antifungal metabolite, oosporein, was isolated from the culture of Verticillium psalliotae that produced the antagonistic effects on Phytophthora infestans. Oosporein exhibited a significant growth-inhibitory effect on P. infestans in comparison with other phytopathogenic fungi.

Download Full-text

IN-VITROSTUDIES ON ANTIFUNGALACTIVITY OF SOMEMISTLETOE SPECIES

International Journal of Advanced Research ◽

10.21474/ijar01/13030 ◽

2021 ◽

Vol 9 (06) ◽

pp. 420-427

Author(s):

R. Neelima ◽

◽

B. Sujatha ◽

N.V. Ramana ◽

B.V. Rao ◽

...

Keyword(s):

Antifungal Activity ◽

Ethyl Acetate ◽

Phytophthora Infestans ◽

Inhibitory Activity ◽

Sclerotium Rolfsii ◽

Diffusion Method ◽

Disc Diffusion ◽

Disc Diffusion Method ◽

Leaf Extracts

In vitro evaluation of antifungal activity by disc diffusion method was carried out on leaf extracts of D.falcata, D. falcata var pubescens, V. monoicum and V. orientale and stem extracts of D. falcata, D. falcata var pubescens, V. articulatum and V.orientale using three different solvents viz., methanol, n-hexane and ethyl acetate. The antifungal activity was tested on three fungal strains include Fusarium oxysporum, Phytophthora infestans, Sclerotium rolfsii. Overall leaf extracts exerted better inhibitory activity than stem counterparts. Among all, only V. orientale was effective against the three fungal species.Compared to stem extracts, leaf extracts of D. falcata var pubescens have shown higher antifungal activity.

Download Full-text

Antifungal activity to Phytophthora infestans and toxicity to tuber tissue of several potato phytoalexins.

Japanese Journal of Phytopathology ◽

10.3186/jjphytopath.51.494 ◽

1985 ◽

Vol 51 (4) ◽

pp. 494-497 ◽

Cited By ~ 6

Author(s):

Norio SATO ◽

Yuko YOSHIZAWA ◽

Hiroshi MIYAZAKI ◽

Akio MURAI

Keyword(s):

Antifungal Activity ◽

Phytophthora Infestans ◽

Tuber Tissue

Download Full-text

Antifungal activity of chitosan against Phytophthora infestans, the pathogen of potato late blight

International Journal of Biological Macromolecules ◽

10.1016/j.ijbiomac.2020.11.016 ◽

2021 ◽

Vol 166 ◽

pp. 1365-1376 ◽

Cited By ~ 1

Author(s):

Xiaoqing Huang ◽

Ziyue You ◽

Yang Luo ◽

Chengji Yang ◽

Jie Ren ◽

...

Keyword(s):

Antifungal Activity ◽

Late Blight ◽

Phytophthora Infestans ◽

Potato Late Blight

Download Full-text

Comparative Analysis of Extracts of Nigella sativa Exhibiting Antifungal Activity against the Oomycete Phytophthora infestans

Chemistry of Natural Compounds ◽

10.1007/s10600-013-0803-x ◽

2013 ◽

Vol 49 (5) ◽

pp. 985-987 ◽

Cited By ~ 1

Author(s):

Yu. I. Oshchepkova ◽

O. N. Veshkurova ◽

Sh. I. Salikhov ◽

D. V. Zaitsev ◽

A. N. Smirnov ◽

...

Keyword(s):

Comparative Analysis ◽

Antifungal Activity ◽

Phytophthora Infestans ◽

Nigella Sativa

Download Full-text

Protein-protein interaction and molecular dynamics of Iturin A gene on effector proteins Phytophthora infestans

Combinatorial Chemistry & High Throughput Screening ◽

10.2174/1386207323666200720012054 ◽

2020 ◽

Vol 23 ◽

Author(s):

Bhimanagoud Kumbar ◽

Shivananda Kandagalla ◽

Bharath B R ◽

Sharath B S ◽

Riaz Mahmood

Keyword(s):

Molecular Dynamics ◽

Antifungal Activity ◽

Phytophthora Infestans ◽

Protein Interaction ◽

In Silico ◽

Plant Pathogens ◽

Effector Proteins ◽

P Value ◽

Iturin A ◽

Protein Protein Interaction

Aim And Objectives: Phytophthora infestans (Mont.) de Bary, fungal pathogen it causes late blight, which results in devastating economic loss among the Solanaceae. The bacillus lipopeptides shows the antagonistic activity against the many plant pathogens, among bacillus lipopeptides Iturin A reported as the antifungal gene. Hence, to understand the in silico antifungal activity, we have selected gene iturin A (AXN89987) produced by Bacillus spp to check the molecular dynamics study with the effector proteins of the P. infestanse. In this concern known effectors proteins of P. infestans were subjected to the protein-protein interaction and followed by simulation. Material and Method: Iturin A gene was amplified using the soil bacterium Bacillus subtilis with gene specific primers. Cloned into pTZ 57R/T vector and confirmed by sequencing. To get better insight the protein model was developed for Iturin A using Modeller 9.17, also for the effector proteins by using PDB structure of ID 4MRT (Phosphopantetheine Transferase Sfp) and 1QR0 (4'-phosphopantetheinyl moiety of coenzyme A) as template it shares the identity 72% and expected P-value: 3e-121 respectively. The model quality was assessed using ProSA and PROCHECK programs. Results: The potency of modelled protein against effector proteins of P. infestans were evaluated in silico using the HADDOCK server and the results showed the high affinity of Iturin A toward the effector protein Host ATG8 (PDB-5L83). Finally, the simulation was performed to the docked conformation of Iturin A with Host ATG8 to further understand the stability of the complex using Desmond program. Conclusion: Altogether the protein-protein interaction and simulation study propose a new methodology and intern it also attempted to uncover possible antifungal activity of iturin A against effector proteins of P. infestans.

Download Full-text

Origanum majorana L. Essential Oil-Associated Polymeric Nano Dendrimer for Antifungal Activity against Phytophthora infestans

Materials ◽

10.3390/ma12091446 ◽

2019 ◽

Vol 12 (9) ◽

pp. 1446 ◽

Cited By ~ 10

Author(s):

Vu Minh Thanh ◽

Le Minh Bui ◽

Long Giang Bach ◽

Ngoc Tung Nguyen ◽

Hoa Le Thi ◽

...

Keyword(s):

Antifungal Activity ◽

Essential Oil ◽

Phytophthora Infestans ◽

Electron Spectroscopy ◽

Gas Chromatography Mass Spectrometry ◽

Resonance Spectroscopy ◽

Transmission Electron ◽

Ft Ir ◽

Origanum Majorana ◽

Tga Analysis

In this study, the introduction of Origanum majorana L. essential oil into a polyamidoamine (PAMAM) G4.0 dendrimer was performed for creation of a potential nanocide against Phytophthora infestans. The characteristics of marjoram oil and PAMAM G4.0 was analyzed using transmission electron spectroscopy (TEM), nuclear magnetic resonance spectroscopy (1H-NMR) and gas chromatography mass spectrometry (GC-MS). The success of combining marjoram oil with PAMAM G4.0 was evaluated by FT-IR, TGA analysis, and the antifungal activity of this system was also investigated. The results showed that the antifungal activity of oil/PAMAM G4.0 was high and significantly higher than only PAMAM G4.0 or marjoram essential oil. These results indicated that the nanocide oil/PAMAM G4.0 helped strengthen and prolong the antifungal properties of the oil.

Download Full-text