A comparative study of the total phenol and flavonoid contents and biological activities of different medicinal parts of Penthorum chinense Pursh

Author(s):  
Liang Liu ◽  
Chen Hu ◽  
Meijia Zou ◽  
Yue Zhao ◽  
Xin Luo ◽  
...  
2020 ◽  
Vol 11 (9) ◽  
pp. 7925-7934
Author(s):  
Yi-Chao Du ◽  
Li Lai ◽  
Hao Zhang ◽  
Fu-Rui Zhong ◽  
Huan-Li Cheng ◽  
...  

In this study, kaempferol (KA) ameliorates APAP-induced hepatotoxicity by activating HO-1/NQO1 and inhibiting HMGB1/TLR4/NF-κB signaling and NLRP3 inflammasome activation.


2019 ◽  
pp. 1-5 ◽  
Author(s):  
Davlat Kh. Akramov ◽  
Gokhan Zengin ◽  
Sun Chul Kang ◽  
Komiljon Sh. Tojibaev ◽  
Mohamad Fawzi Mahomoodally ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-13 ◽  
Author(s):  
Li-mei Lin ◽  
Ling-jia Zhao ◽  
Jing Deng ◽  
Su-hui Xiong ◽  
Jie Tang ◽  
...  

Penthorum chinense Pursh (PCP) is a kind of functional food or medicine for liver protection. In the present work, Plackett-Burman design, steepest ascent method, and response surface methodology (RSM) were employed to obtain maximum total sugar yield. The experimental yield of 6.91% indicated a close agreement with the predicted yield of 7.00% of the model under optimized conditions. The major polysaccharide fraction (PCPP-1a) from PCPP was purified and identified as acidic polysaccharides with a high content of uronic acid (FT-IR, UV, HPGPC). PCPP had similar monosaccharide profile with PCPP-1a but was rich in galacturonic acid (HPLC). Both of PCPP and PCPP-1a possessed strong hydroxyl radical scavenging, DPPH radical scavenging, and Fe2+ chelating activities. Moreover, they were revealed to show strong anti-inflammatory activities by inhibiting NO, TNF-α, and IL-1β release compared to LPS treatment in RAW264.7 cells. These data suggest that the polysaccharides from PCP could be potential natural products for treating ROS and inflammatory-related diseases.


Molecules ◽  
2015 ◽  
Vol 20 (4) ◽  
pp. 6443-6453 ◽  
Author(s):  
Yangyang Hu ◽  
Shengpeng Wang ◽  
Anqi Wang ◽  
Ligen Lin ◽  
Meiwan Chen ◽  
...  

2015 ◽  
Vol 6 (5) ◽  
pp. 1510-1517 ◽  
Author(s):  
Yi-Wei Cao ◽  
Yun Jiang ◽  
Da-Yong Zhang ◽  
Xiao-Jing Zhang ◽  
Yuan-Jia Hu ◽  
...  

Aqueous extracts ofPenthorum chinensePursh, a health food and folk medicine, protects against acute alcohol-induced liver injury.


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