Antifouling effect of bioactive compounds from selected marine organisms in the Obhur Creek, Red Sea

2016 ◽  
Vol 15 (3) ◽  
pp. 465-470
Author(s):  
Abdulmohsin Al-Sofyani ◽  
N. Marimuthu ◽  
J. Jerald Wilson ◽  
Arulazhagan Pugazhendi ◽  
Jeyakumar Dhavamani
Keyword(s):  
Bioactive Compounds ◽  
Red Sea ◽  
Marine Organisms

Production of Novel Bioactive Compounds by the Bacteria Associated with Some Marine Sponges of Gulf of Mannar and Palk Bay, Southeast Coast of India

2018 ◽  
Vol 6 (8) ◽  
pp. 183
Author(s):  
V. Ramadas ◽  
G. Chandralega
Keyword(s):  
Bioactive Compounds ◽  
Bacterial Species ◽  
Marine Sponges ◽  
Marine Organisms ◽  
Gulf Of Mannar ◽  
Bacterial Symbionts ◽  
Palk Bay ◽  
Excellent Source

Sponges, exclusively are aquatic and mostly marine, are found from the deepest oceans to the edge of the sea. There are approximately 15,000 species of sponges in the world, of which, 150 occur in freshwater, but only about 17 are of commercial value. A total of 486 species of sponges have been identified in India. In the Gulf of Mannar and Palk Bay a maximum of 319 species of sponges have been recorded. It has been proved that marine organisms are excellent source of bioactive secondary metabolites and number of compounds of originated from marine organisms had been reported to possess in-vitro and in-vivo immuno stimulatory activity. Extracts from 20 sponge species were tested for bacterial symbionts and bioactive compounds were isolated from such associated bacterial species in the present study.

Nutraceuticals from Marine Bionetworks

2019 ◽  
Vol 15 (4) ◽  
pp. 338-344
Author(s):  
Abhitav Tiwari ◽  
Shambhawi Pritam ◽  
Keerti Mishra ◽  
Mehshara Khan ◽  
Neeraj Upmanyu ◽  
...  
Keyword(s):  
Dietary Supplements ◽  
Bioactive Compounds ◽  
Daily Basis ◽  
Marine Organisms ◽  
Bioactive Molecules ◽  
Natural Sources ◽  
Nutraceutical Compounds ◽  
Potential Sources ◽  
Immense Potential ◽  
Potential Use

“Nutrition” and “Pharmaceutical” together build up the perception of “Nutraceuticals” that refer to the food or dietary supplements that help to incorporate additional health benefits to the fundamental sustenance accomplished on daily basis. Each nutraceutical contains one or more bioactive molecules that are usually obtained by chemical and/ or biotechnological synthesis or by extraction from natural sources. Among the natural sources, marine bionetwork possess immense potential for the presence of bioactive compounds. Some of these bioactive compounds as isolated from marine sources, have potential use as nutraceuticals. This mini review provides a brief overview of nutraceutical compounds from marine sources that are currently under research and/or have been commercialized. A detailed discussion on the biochemical categories of compounds and the marine organisms that play as potential sources of these bioactive nutraceutical compounds have been included.

Ehrenasterol and biemnic acid; new bioactive compounds from the Red Sea sponge Biemna ehrenbergi

2015 ◽  
Vol 12 ◽  
pp. 296-301 ◽  
Author(s):  
Diaa T.A. Youssef ◽  
Jihan M. Badr ◽  
Lamiaa A. Shaala ◽  
Gamal A. Mohamed ◽  
Faida H. Bamanie
Keyword(s):  
Bioactive Compounds ◽  
Red Sea

scholarly journals Cytotoxic and HIV-1 enzyme inhibitory activities of Red Sea marine organisms

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Mona S Ellithey ◽  
Namrita Lall ◽  
Ahmed A Hussein ◽  
Debra Meyer
Keyword(s):  
Red Sea ◽  
Marine Organisms ◽  
Inhibitory Activities ◽  
Hiv 1

scholarly journals Environmentally Friendly Antifouling Metabolites from Red Sea Organisms

2019 ◽  
Vol 2019 ◽  
pp. 1-15
Author(s):  
Sultan Semran Al-Lihaibi ◽  
Ahmed Abdel-Lateff ◽  
Walied Mohamed Alarif ◽  
Hajer Saeed Alorfi ◽  
Yasuyuki Nogata ◽  
...  
Keyword(s):  
Red Sea ◽  
Sea Cucumber ◽  
Environmentally Friendly ◽  
Marine Organisms ◽  
Balanus Amphitrite ◽  
Soft Corals ◽  
Marine Fauna ◽  
Chromatographic Techniques ◽  
Methanolic Extracts ◽  
Settlement Inhibition

Seventy-one marine organisms representing different classes of marine fauna and flora were collected from the Red Sea. They include sponges, hydrozoan, soft corals, sea cucumber, ascidian, cyanobacteria, and macroalgae. The methanolic extracts were evaluated for their toxicity and settlement inhibition effects by using cultured Balanus amphitrite. Thirty-three extracts displayed antifouling effects: four samples were highly potent at 1 μg/mL with a percentage of settlement inhibition above 31%, twenty-two were potent at 10 μg/mL with a percentage of settlement inhibition between 16 and 30%, and seven were active at 10 μg/mL with a percentage of settlement inhibition between 0 and 15%. Two promising extracts were purified by employing several chromatographic techniques, leading to the isolation of 12 known compounds. The isolated compounds were evaluated for their antifouling activities and demonstrated potent antifouling effects with EC50 values of less than 10 μg/mL.

scholarly journals Anti-Alzheimer’s Molecules Derived from Marine Life: Understanding Molecular Mechanisms and Therapeutic Potential

Marine Drugs ◽  
2021 ◽  
Vol 19 (5) ◽  
pp. 251
Author(s):  
Md. Tanvir Kabir ◽  
Md. Sahab Uddin ◽  
Philippe Jeandet ◽  
Talha Bin Emran ◽  
Saikat Mitra ◽  
...  
Keyword(s):  
Adverse Events ◽  
Bioactive Compounds ◽  
Molecular Mechanisms ◽  
Therapeutic Potential ◽  
Marine Organisms ◽  
Glutamate Excitotoxicity ◽  
Bryostatin 1 ◽  
Marine Life ◽  
Synthetic Drugs ◽  
Aβ Aggregation

Alzheimer’s disease (AD) is a devastating neurodegenerative disease and the most common cause of dementia. It has been confirmed that the pathological processes that intervene in AD development are linked with oxidative damage to neurons, neuroinflammation, tau phosphorylation, amyloid beta (Aβ) aggregation, glutamate excitotoxicity, and cholinergic deficit. Still, there is no available therapy that can cure AD. Available therapies only manage some of the AD symptoms at the early stages of AD. Various studies have revealed that bioactive compounds derived from marine organisms and plants can exert neuroprotective activities with fewer adverse events, as compared with synthetic drugs. Furthermore, marine organisms have been identified as a source of novel compounds with therapeutic potential. Thus, there is a growing interest regarding bioactive compounds derived from marine sources that have anti-AD potentials. Various marine drugs including bryostatin-1, homotaurine, anabaseine and its derivative, rifampicins, anhydroexfoliamycin, undecylprodigioisin, gracilins, 13-desmethyl spirolide-C, and dictyostatin displayed excellent bioavailability and efficacy against AD. Most of these marine drugs were found to be well-tolerated in AD patients, along with no significant drug-associated adverse events. In this review, we focus on the drugs derived from marine life that can be useful in AD treatment and also summarize the therapeutic agents that are currently used to treat AD.

scholarly journals Secondary Metabolites from Marine Sources with Potential Use as Leads for Anticancer Applications

Molecules ◽  
2021 ◽  
Vol 26 (14) ◽  
pp. 4292
Author(s):  
Ana C. S. Veríssimo ◽  
Mário Pacheco ◽  
Artur M. S. Silva ◽  
Diana C. G. A. Pinto
Keyword(s):  
Bioactive Compounds ◽  
Anticancer Agents ◽  
Sea Urchins ◽  
Therapeutic Agents ◽  
Marine Organisms ◽  
Marine Origin ◽  
Anticancer Properties ◽  
The Past ◽  
New Compounds ◽  
Potential Use

The development of novel anticancer agents is essential to finding new ways to treat this disease, one of the deadliest diseases. Some marine organisms have proved to be important producers of chemically active compounds with valuable bioactive properties, including anticancer. Thus, the ocean has proved to be a huge source of bioactive compounds, making the discovery and study of these compounds a growing area. In the last few years, several compounds of marine origin, which include algae, corals, and sea urchins, have been isolated, studied, and demonstrated to possess anticancer properties. These compounds, mainly from securamines and sterols families, have been tested for cytotoxic/antiproliferative activity in different cell lines. Bioactive compounds isolated from marine organisms in the past 5 years that have shown anticancer activity, emphasizing the ones that showed the highest cytotoxic activity, such as securamines H and I, cholest-3β,5α,6β-triol, (E)-24-methylcholest-22-ene-3β,5α,6β-triol, 24-methylenecholesta-3β,5α,6β-triol, and 24-methylcholesta-3β,5α,6β-triol, will be discussed in this review. These studies reveal the possibility of new compounds of marine origin being used as new therapeutic agents or as a source of inspiration to develop new therapeutic agents.

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