Chapter 10 Bioactive Compounds from Marine Organisms and Cultivated Blue-Green Algae

Author(s):  
Jon S. Mynderse ◽  
Louise W. Crandall ◽  
John H. Cardellina
2021 ◽  
Vol 9 (5) ◽  
pp. 543-571
Author(s):  
Ritu Chauhan ◽  
◽  
Abhishek Chauhan ◽  
Ashutosh Tripathi ◽  
Anuj Ranjan ◽  
...  

COVID-19 pandemic has taught the world researchers the urgent need for new sources and novel pharmaceuticals not only for existing diseases but also for both seasonal epidemics and future pandemics. Pharmaceutical drug discoveries for the past fifty years depended deeply on the procedure of empirical transmission of a huge number of pure bioactive compounds to provide new leads. The screening of extracts or isolating compounds is a common way to discover novel biologically active molecules. Most of the valuable Blue-Green algal metabolites are concentrated in their biomass. For existence in nature, Blue-Green algae (BGA) secrete and contain various organic substances like proteins, fatty acids, vitamins, pigments, primary and secondary metabolites, and these compounds are explored for potential biological activities such as antibacterial, antifungal, antiviral (including the anti-SARS-CoV-2 virus that causes COVID-19), anticancer, antioxidant, antidiabetic, protease inhibitory activity, anti-inflammatory activity, etc. Due to their diverse application, pharmaceutical companies have shown commercial interest in the Blue-green algal group for the discovery and development of novel molecules to combat deadly diseases for the benefit of society and mankind. The current review paper highlights and discusses the diverse pharmaceutical potential of laboratory-grown cultures of BGA along with comprehensive and current knowledge on bioactive compounds discovered by researchers globally.


Author(s):  
S. І. Kryshtopa ◽  
L. І. Kryshtopa ◽  
М. М. Hnyp ◽  
І. М. Mykytii

This article considers usage of blue-green algae as biomaterials for creation of motor biofuels. Proliferation of blue-green algae leads to water rotting, destruction of aquatic ecosystems and destruction of rivers and lakes that is why clearing of water bodies from blue-green algae is an urgent task. The object of the study is effect of blended biodiesel fuels from blue-green algae on the environmental and energy performances for the diesel engine. The purpose of the work is experimental study of changes of power and ecological characteristics of automobile diesel engines using petroleum diesel and their mixtures with biofuels derived from blue-green algae. Methods of research are experimental, laboratory ones. Laboratory researches were carried out on an experimental installation based on the serial diesel engine D21A1. As a result of performed experimental researches dependences of changing of the effective engine power on the use of diesel fuel and a mixture of diesel fuel with the received bioactive supplements based on methyl esters of the lipid fraction of blue-green algae Chroococcfles in the amount of 5, 10 and 20 % were established. It has been experimentally established that the effective power of an engine using a mixture of diesel fuel with the derived bioactive compounds based on methyl esters of the lipid fraction of blue-green algae Chroococcfles in the amount of 5, 10 and 20 % will decrease by an average of 0,9, 1,8 and 3,5 %. It has been experimentally determined that the content of carbon monoxide in the use of a mixture of diesel fuel with the derived bioactive compounds based on methyl esters of the lipid fraction of blue-green algae Chroococcfles in the amount of 5, 10 and 20 % will decrease by an average of 6,5, 13,9 and 28,7 %. The obtained results allow to optimize the choice of fuels for power systems of internal combustion engines and to reduce emissions of harmful substances in exhaust gases of automobile diesel engines.


2021 ◽  
Author(s):  
Ayesha Algade Amadu ◽  
Kweku Amoako Atta deGraft-Johnson ◽  
Gabriel Komla Ameka

Cyanobacteria also known as blue-green algae are oxygenic photoautotrophs, which evolved ca. 3.5 billion years ago. Because cyanobacteria are rich sources of bioactive compounds, they have diverse industrial applications such as algaecides, antibacterial, antiviral and antifungal agents, hence, their wide use in the agricultural and health sectors. Cyanobacterial secondary metabolites are also important sources of enzymes, toxins, vitamins, and other pharmaceuticals. Polyhydroxy- alkanoates (PHA) which accumulate intracellularly in some cyanobacteria species can be used in the production of bioplastics that have properties comparable to polypropylene and polyethylene. Some cyanobacteria are also employed in bioremediation as they are capable of oxidizing oil components and other complex organic compounds. There are many more possible industrial applications of cyanobacteria such as biofuel, biofertilizer, food, nutraceuticals, and pharmaceuticals. Additionally, the metabolic pathways that lead to the production of important cyanobacterial bioactive compounds are outlined in the chapter along with commercial products currently available on the market.


2020 ◽  
Vol 1 (46) ◽  
pp. 153-162
Author(s):  
Kryzhanivskyi Y ◽  
◽  
Kryshtopa S ◽  
Kryshtopa L ◽  
Hnyp M ◽  
...  

This article considers usage of blue-green algae as biomaterials for creation of motor biofuels. The object of the study is effect of blended biodiesel fuels from blue-green algae on the environmental and energy performances for the diesel engine. The purpose of the work is experimental study of changes of power and ecological characteristics of automobile diesel engines using petroleum diesel and their mixtures with biofuels derived from blue-green algae. Methods of research are experimental, laboratory ones. As a result of performed experimental researches dependences of changing of the effective engine power on the use of diesel fuel and a mixture of diesel fuel with the received bioactive supplements based on methyl esters of the lipid fraction of blue-green algae Chroococcfles in the amount of 5, 10 and 20% were established. It has been experimentally established that the effective power of an engine using a mixture of diesel fuel with the derived bioactive compounds based on methyl esters of the lipid fraction of blue-green algae Chroococcfles in the amount of 5, 10 and 20% will decrease by an average of 0,9, 1,8 and 3,5 %. It has been experimentally determined that the content of carbon monoxide in the use of a mixture of diesel fuel with the derived bioactive compounds based on methyl esters of the lipid fraction of blue-green algae Chroococcfles in the amount of 5, 10 and 20 % will decrease by an average of 6,5, 13,9 and 28,7 %. The obtained results allow to optimize the choice of fuels for power systems of internal combustion engines and to reduce emissions of harmful substances in exhaust gases of automobile diesel engines. KEY WORDS: BIOFUELS, DIESEL ENGINE, ALGAE, POWERFUL CHARACTERISTICS, ENVIRONMENTAL INDICATORS.


Author(s):  
L. V. Leak

Electron microscopic observations of freeze-fracture replicas of Anabaena cells obtained by the procedures described by Bullivant and Ames (J. Cell Biol., 1966) indicate that the frozen cells are fractured in many different planes. This fracturing or cleaving along various planes allows one to gain a three dimensional relation of the cellular components as a result of such a manipulation. When replicas that are obtained by the freeze-fracture method are observed in the electron microscope, cross fractures of the cell wall and membranes that comprise the photosynthetic lamellae are apparent as demonstrated in Figures 1 & 2.A large portion of the Anabaena cell is composed of undulating layers of cytoplasm that are bounded by unit membranes that comprise the photosynthetic membranes. The adjoining layers of cytoplasm are closely apposed to each other to form the photosynthetic lamellae. Occassionally the adjacent layers of cytoplasm are separated by an interspace that may vary in widths of up to several 100 mu to form intralamellar vesicles.


Author(s):  
V. Ramadas ◽  
G. Chandralega

Sponges, exclusively are aquatic and mostly marine, are found from the deepest oceans to the edge of the sea. There are approximately 15,000 species of sponges in the world, of which, 150 occur in freshwater, but only about 17 are of commercial value. A total of 486 species of sponges have been identified in India. In the Gulf of Mannar and Palk Bay a maximum of 319 species of sponges have been recorded. It has been proved that marine organisms are excellent source of bioactive secondary metabolites and number of compounds of originated from marine organisms had been reported to possess in-vitro and in-vivo immuno stimulatory activity. Extracts from 20 sponge species were tested for bacterial symbionts and bioactive compounds were isolated from such associated bacterial species in the present study.


2017 ◽  
Vol 40 (1) ◽  
pp. 47-62 ◽  
Author(s):  
I. M. Chung ◽  
S. H. Kim ◽  
Y.T. Oh ◽  
M. Ali ◽  
A. Ahmad

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