Artificial Cold Wave-Induced Cerebral Infarction in Rats with Carotid Atherosclerosis

Mangrove forests growing at the poleward edges of their geographic distribution are occasionally subject to freezing (<0 °C) and cold wave (>0 °C) events. Cold wave effects on mangrove trees are well documented and adaptation to cold stress has been reported for local mangrove populations in the North Atlantic. However, there is less understanding of effects of cold waves on mangroves in the northern Pacific, especially at the regional scale. Moreover, it is unclear if cold tolerant mangrove species of North Asia display variation in resistance to cold temperatures across their geographic distribution. Using a cold wave event that occurred in January 2021, we evaluated the effects of low temperatures on vegetation index (VI) change (relative to a recent five-year baseline) for mangrove forests dominated by Kandelia obovata (Rhizophoraceae) and Avicennia marina (Acanthaceaee) at the northern edge of their geographical range. We used two VIs derived from Sentinel-2 imagery as indicators for canopy health: the normalized difference infrared index (NDII) and the chlorophyll red-edge index (ChlRE), which reflect forest canopy water content and chlorophyll concentration, respectively. We isolated the cold wave effects on the forest canopy from phenology (i.e., cold wave induced deviation from a five-year baseline) and used multiple linear regression to identify significant climatic predictors for the response of mangrove forest canopy VI change to low temperatures. For areas where the cold wave resulted in temperatures <10 °C, immediate decreases in both VIs were observed, and the VI difference relative to the baseline was generally greater at 30-days after the cold wave than when temperatures initially recovered to baseline values, showing a slight delay in VI response to cold wave-induced canopy damage. Furthermore, the two VIs did not respond consistently suggesting that cold-temperature induced changes in mangrove canopy chlorophyll and water content are affected independently or subject to differing physiological controls. Our results confirm that local baseline (i.e., recent past) climate predicts canopy resistance to cold wave damage across K. obovata stands in the northern Pacific, and in congruence with findings from New World mangroves, they imply geographic variation in mangrove leaf physiological resistance to cold for Northern Pacific mangroves.

Download Full-text

Association of carotid atherosclerosis and recurrent cerebral infarction in the Chinese population: a meta-analysis

Neuropsychiatric Disease and Treatment ◽

10.2147/ndt.s124386 ◽

2017 ◽

Vol Volume 13 ◽

pp. 527-533 ◽

Cited By ~ 4

Author(s):

Jianping Liu ◽

Yun Zhu ◽

Yuhuai Wu ◽

Yan Liu ◽

Zhaowei Teng ◽

...

Keyword(s):

Cerebral Infarction ◽

Chinese Population ◽

Carotid Atherosclerosis ◽

Meta Analysis

Download Full-text

A12352 Relationship between estimated glomerular filtration rate and carotid atherosclerosis in hypertension with acute cerebral infarction

Journal of Hypertension ◽

10.1097/01.hjh.0000548861.77405.80 ◽

2018 ◽

Vol 36 ◽

pp. e211

Author(s):

Jie Wu ◽

Kuang Peng ◽

Jin Zou ◽

Jun-Bi Zhao ◽

...

Keyword(s):

Glomerular Filtration Rate ◽

Cerebral Infarction ◽

Glomerular Filtration ◽

Filtration Rate ◽

Carotid Atherosclerosis ◽

Estimated Glomerular Filtration Rate ◽

Acute Cerebral Infarction

Download Full-text

Severe erythematotelangiectatic rosacea with cold wave-induced epidermal necrosis treated with carvedilol combined with brimonidine gel

Dermatologic Therapy ◽

10.1111/dth.12501 ◽

2017 ◽

Vol 30 (4) ◽

pp. e12501 ◽

Cited By ~ 1

Author(s):

Chaw-Ning Lee ◽

Julia Yu-Yun Lee

Keyword(s):

Cold Wave ◽

Wave Induced ◽

Epidermal Necrosis

Download Full-text

The Relationship between the Mean Platelet Volume and Carotid Atherosclerosis and Prognosis in Patients with Acute Cerebral Infarction

BioMed Research International ◽

10.1155/2020/6685740 ◽

2020 ◽

Vol 2020 ◽

pp. 1-6

Author(s):

Min Xu ◽

Xiao-ying He ◽

Pan Huang

Keyword(s):

Cerebral Infarction ◽

Mean Platelet Volume ◽

Poor Prognosis ◽

Carotid Atherosclerosis ◽

Independent Predictor ◽

Multivariate Logistic Regression Analysis ◽

Acute Cerebral Infarction ◽

Observation Group ◽

Platelet Volume ◽

The Relationship

Objective. To investigate the relationship between mean platelet volume (MPV) level and carotid atherosclerosis and prognosis in patients with acute cerebral infarction. Methods. A retrospectively included 160 patients with acute cerebral infarction classified by TOAST classification as aortic atherosclerosis as the observation group. To analyze the relationship between MPV and carotid atherosclerosis, and use receiver operating characteristic (ROC) curves to analyze the role of MPV in predicting the prognosis of acute cerebral infarction in the observation group, grouping patients with different MPV by cut-off value, and analyze the differences in factors between the two groups of patients.Results. MPV has a positive correlation with carotid atherosclerosis in patients with acute cerebral infarction. Multivariate logistic regression analysis revealed that increased MPV was an independent predictor of poor functional outcome in patients with acute cerebral infarction (Odds Ratio (OR): 6.152, 95% CI: 2.385-13.625, P < 0.01 ). ROC curve analysis showed that the area under the curve for MPV to predict poor prognosis was 0.868 (95% CI: 0.787-949, P < 0.01 ). The cutoff value, sensitivity, and specificity were 12.65, 76.2%, and 87.6%. Compared with patients with MPV < 12.65 at admission, patients with higher MPV levels ( MPV ≥ 12.65 ) at admission have larger infarct size, more severe carotid artery stenosis, poor short-term prognosis, and higher mortality. Conclusion. MPV level is closely related to the degree of carotid atherosclerosis in patients with acute cerebral infarction, and it is also an independent predictor of poor prognosis in patients with acute cerebral infarction at 3 months.

Download Full-text

Baseline silent cerebral infarction in the Asymptomatic Carotid Atherosclerosis Study.

Stroke ◽

10.1161/01.str.25.6.1122 ◽

1994 ◽

Vol 25 (6) ◽

pp. 1122-1129 ◽

Cited By ~ 72

Author(s):

T Brott ◽

T Tomsick ◽

W Feinberg ◽

C Johnson ◽

J Biller ◽

...

Keyword(s):

Cerebral Infarction ◽

Carotid Atherosclerosis ◽

Asymptomatic Carotid ◽

Silent Cerebral Infarction

Download Full-text

Association of cerebral infarction with carotid atherosclerosis, triglycerides, C-reactive protein

International Journal of Cardiology ◽

10.1016/j.ijcard.2011.08.511 ◽

2011 ◽

Vol 152 ◽

pp. S15 ◽

Cited By ~ 1

Author(s):

Shangying Jia

Keyword(s):

Cerebral Infarction ◽

Carotid Atherosclerosis ◽

C Reactive Protein ◽

Reactive Protein

Download Full-text

Abstract WP197: Increased Carotid Intima-Media Thickness is Associated ith Incident Coronary Heart Disease and Stroke in a Japanese General Population With a 12.6-year Follow-up: The Suita Study

Stroke ◽

10.1161/str.48.suppl_1.wp197 ◽

2017 ◽

Vol 48 (suppl_1) ◽

Author(s):

Yoshihiro Kokubo ◽

Makoto Watanabe ◽

Aya Higashiyama ◽

Yoko M. Nakao ◽

Misa Takegami ◽

...

Keyword(s):

Coronary Heart Disease ◽

Carotid Artery ◽

Cerebral Infarction ◽

Carotid Atherosclerosis ◽

Intima Media Thickness ◽

Carotid Intima Media Thickness ◽

Carotid Imt ◽

Incident Coronary Heart Disease ◽

The Mean

Introduction: Carotid intima-media thickness (IMT) is increasingly used as a subclinical marker of cardiovascular disease. However, few studies have examined the association between IMT and incident coronary heart disease (CHD) and stroke in non-Westerners. We assessed the hypothesis that carotid atherosclerosis is a predictor of CHD and stroke events in a general urban Japanese population. Methods: We studied 4,751 Japanese (2181 men and 2570 women, mean age 59.8 years, without stroke or CHD at the baseline) who completed a baseline survey and carotid atherosclerosis in the Suita Study, and were then followed for an average of 12.6 years. Carotid atherosclerosis was evaluated by high-resolution ultrasonography with atherosclerotic indexes of IMT in the common carotid artery (CCA) and the carotid artery bulb. Mean IMT was defined as the mean of the IMT of the proximal and distal walls for both sides of the CCA at a point 10 mm proximal to the beginning of the dilation of each carotid artery bulb. Max-CCA and Max-Bulb were defined as the maximum IMT in the CCA and bulb areas, respectively. We used adjusted Cox proportional-hazards models to compare the risk of CHD and stroke by use of mean and maximum carotid IMT in the CCA and bulb areas. Results: During the follow-up, we documented 145 cerebral infarctions, 58 hemorrhagic strokes, 20 unclassified strokes, and 159 CHD. The adjusted hazard ratios (HRs; 95% confidence intervals [CI], P for trend [P trend]) in the fourth quartile (≥ 0.95 mm) of the mean IMT for strokes, cerebral infarction, and CHD were 3.13 (1.48-6.63, P trend = 0.002), 3.34 (1.33-8.37, P trend = 0.002), and 1.93 (0.96-3.88, P trend <0.0001), respectively, compared with the first quartile (<0.775 mm). The adjusted HRs (95% CI) in the fourth quartiles of Max-CCA (≥1.10 mm) and Max-BIF (≥1.55 mm) were 2.48 (1.10-5.62, P trend = 0.07) and 3.28 (1.40-7.69, P trend <0.0001) in stroke, 1.87 (0.75-4.659, P trend = 0.07) and 2.83 (1.05-7.63, P trend = 0.005) in cerebral infarction, and 3.07 (1.18-8.04, P trend <0.0001) and 6.01 (2.02-17.9, P trend <0.0001) in CHD, respectively, compared with the first quartiles (<0.9 mm). Conclusions: Carotid IMT, especially Max-BIF was a strong predictor of stroke, cerebral infarction, and CHD in a Japanese urban general population.

Download Full-text