Role of Amyloid Precursor Protein (APP) and Its Derivatives in the Biology and Cell Fate Specification of Neural Stem Cells

2018 ◽  
Vol 55 (9) ◽  
pp. 7107-7117 ◽  
Author(s):  
Raquel Coronel ◽  
Adela Bernabeu-Zornoza ◽  
Charlotte Palmer ◽  
Mar Muñiz-Moreno ◽  
Alberto Zambrano ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Amyloid Precursor Protein ◽  
Cell Fate ◽  
Precursor Protein ◽  
Cell Fate Specification ◽  
Fate Specification

scholarly journals The RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs

2015 ◽  
Vol 43 (5) ◽  
pp. 2638-2654 ◽  
Author(s):  
Sarah Nicklas ◽  
Satoshi Okawa ◽  
Anna-Lena Hillje ◽  
Laura González-Cano ◽  
Antonio del Sol ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Cell Fate ◽  
Rna Helicase ◽  
Cell Fate Specification ◽  
Fate Specification

The Balance Between Self-Renewal and Differentiation of Human Neural Stem Cells Requires the Amyloid Precursor Protein

2021 ◽  
Author(s):  
Khadijeh Shabani ◽  
Julien Pigeon ◽  
Marwan Benaissa Touil Zariouh ◽  
Tengyuan Liu ◽  
Azadeh Saffarian ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Amyloid Precursor Protein ◽  
Precursor Protein ◽  
Self Renewal ◽  
Human Neural Stem Cells

Genes necessary for C. elegans cell and growth cone migrations

Development ◽  
1997 ◽  
Vol 124 (9) ◽  
pp. 1831-1843 ◽  
Author(s):  
W.C. Forrester ◽  
G. Garriga
Keyword(s):  
Cell Fate ◽  
Single Gene ◽  
Growth Cones ◽  
Cell Fate Specification ◽  
Fate Specification ◽  
C Elegans ◽  
Final Destination ◽  
Multiple Cell

The migrations of cells and growth cones contribute to form and pattern during metazoan development. To study the mechanisms that regulate cell motility, we have screened for C. elegans mutants defective in the posteriorly directed migrations of the canal-associated neurons (CANs). Here we describe 14 genes necessary for CAN cell migration. Our characterization of the mutants has led to three conclusions. First, the mutations define three gene classes: genes necessary for cell fate specification, genes necessary for multiple cell migrations and a single gene necessary for final positioning of migrating cells. Second, cell interactions between the CAN and HSN, a neuron that migrates anteriorly to a position adjacent to the CAN, control the final destination of the HSN cell body. Third, C. elegans larval development requires the CANs. In the absence of CAN function, larvae arrest development, with excess fluid accumulating in their pseudocoeloms. This phenotype may reflect a role of the CANs in osmoregulation.

Stem Cell Fate Specification: Role of Master Regulatory Switch Transcription Factor PU.1 in Differential Hematopoiesis

2005 ◽  
Vol 14 (2) ◽  
pp. 140-152 ◽  
Author(s):  
Gurudutta U. Gangenahalli ◽  
Pallavi Gupta ◽  
Daman Saluja ◽  
Yogesh K. Verma ◽  
Vimal Kishore ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Stem Cell ◽  
Cell Fate ◽  
Cell Fate Specification ◽  
Stem Cell Fate ◽  
Fate Specification

scholarly journals The role of the Rx homeobox gene in retinal progenitor proliferation and cell fate specification

2018 ◽  
Vol 151 ◽  
pp. 18-29 ◽  
Author(s):  
H.M. Rodgers ◽  
V.J. Huffman ◽  
V.A. Voronina ◽  
M. Lewandoski ◽  
P.H. Mathers
Keyword(s):  
Cell Fate ◽  
Homeobox Gene ◽  
Cell Fate Specification ◽  
Fate Specification ◽  
Retinal Progenitor
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