Relation Between Posterior Canal Benign Paroxysmal Positional Vertigo and Vitamin D Deficiency

2022 ◽  
Author(s):  
Kanika Sharma ◽  
Tarun Ojha ◽  
Rajendra Dabaria ◽  
Biban Chhabra ◽  
Bhargavi Bhaskar Trivedi ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Benign Paroxysmal Positional Vertigo ◽  
Posterior Canal ◽  
Positional Vertigo ◽  
Paroxysmal Positional Vertigo

scholarly journals Investigating the Association Between Serum Vitamin D Deficiency and Idiopathic Benign Paroxysmal Positional Vertigo

2020 ◽  
Vol 7 (3) ◽  
pp. 122-126
Author(s):  
Jignesh Dhirubhai Dhameliya ◽  
Umesh Kumar Chandra ◽  
Sumit Kumar Vishwakarma ◽  
Dattaprasad Ganganpalli ◽  
Archana Verma
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Vitamin D3 ◽  
Benign Paroxysmal Positional Vertigo ◽  
Positive Association ◽  
Posterior Canal ◽  
Positional Vertigo ◽  
Vitamin D Levels ◽  
Vitamin D3 Deficiency ◽  
Paroxysmal Positional Vertigo

Background: It is suggested that there is a positive association between vitamin D deficiency and benign paroxysmal positional vertigo (BPPV). We suggest, as a hypothesis, there is a positive association between vitamin D deficiency and BPPV. The current study aimed to investigate the association between vitamin D levels and BPPV. Methods: The present observational case-control study was planned and conducted on 100 participants (50 cases and 50 controls) in the Department of Neurology, Choithram Hospital & Research Center (CHRC), Indore, MP, India, from January 2018 to December 2018. All consecutive patients with diagnosis of idiopathic BPPV who were above the age of 18 years with a negative neurological status were included. Analyses were performed using SPSS software version 10. Results: BPPV was more common among those aged 50 to 70 years (64%). Out of 100 participants, 72 (72%) had vitamin D deficiency, in which 40 (80%) were cases and 32 (64%) were controls. 32 (64%) patients had posterior canal involved, out of them 20 (40%) were females and 12 (24%) were males, and in both groups posterior canal was more involved. Canal involvement according to gender was not statistically significant (P value=0.45). Mean vitamin D level for cases and controls was 34.9 and 46.5 nmol/L, respectively, and this difference was statically very significant with a p-value of 0.01 (P value < 0.05). Conclusion: According to the findings, there is a statistically significant association between vitamin D3 deficiency and Idiopathic BPPV. It can be noted that vitamin D3 deficiency may be a risk factor for the BPPV.

Relationship between calcium metabolism and benign paroxysmal positional vertigo in north Sardinia population

2020 ◽  
Vol 30 (6) ◽  
pp. 375-382
Author(s):  
Andrea Melis ◽  
Davide Rizzo ◽  
Roberto Gallus ◽  
Maria Eleonora Leo ◽  
Nicola Turra ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Benign Paroxysmal Positional Vertigo ◽  
High Accuracy ◽  
T Score ◽  
Positional Vertigo ◽  
Vitamin D Levels ◽  
The Impact ◽  
Paroxysmal Positional Vertigo ◽  
Group 1

BACKGROUND: Benign paroxysmal positional vertigo (BPPV) has a reported recurrence ranging from 26.8 to 50%. Osteoporosis and Vitamin D deficiency seems to have an impact on recurrence of BPPV. OBJECTIVE: to evaluate the impact of osteoporosis and Vitamin D deficiency on recurrence of BPPV. METHODS: 73 consecutive patients were divided in two groups according to the presence (group 1) or absence (group 0) of a recurrent episode. BMD, femoral and lumbar T-scores and Vitamin D levels were recorded. Statistical analysis was performed to investigate correlations. RESULTS: patients in group 1 had statistically significant lower values of both femoral (–1,62±1,06 vs. –0,53±1,51; p = 0,001), lumbar T-score (–2,10±1,19 vs –0, 53±1.51, p = 0.001) and Vitamin D (19.53±15.33). The values of femoral T-score and Vitamin D could be combined in a model able to properly classify 65.8% of the cases (p = 0.002) as isolated or recurrent BPPV, with high accuracy (AUC 0.710 [0.590 –0.830]). CONCLUSION: present data show a probable correlation between osteoporosis and Vitamin D with recurrent BPPV.

scholarly journals Serum levels of 25-hydroxy vitamin D correlate with idiopathic benign paroxysmal positional vertigo

2019 ◽  
Vol 39 (4) ◽  
Author(s):  
Jing Ding ◽  
Lei Liu ◽  
Wei-Kuan Kong ◽  
Xiao-Bing Chen ◽  
Xudong Liu
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Benign Paroxysmal Positional Vertigo ◽  
Serum Levels ◽  
Chinese Patients ◽  
Control Group ◽  
Binary Logistic Regression Analysis ◽  
Positional Vertigo ◽  
25 Hydroxy Vitamin D ◽  
Paroxysmal Positional Vertigo

Abstract Background: The present study aimed to evaluate serum 25-hydroxy vitamin D (25(OH) D) levels in Chinese patients with idiopathic benign paroxysmal positional vertigo (BPPV) and to investigate the possible relationship between the occurrence and recurrence of idiopathic BPPV and low 25(OH) D levels. Methods: Between 1 January 2017 and 31 May, 2018, consecutively older patients (age, older than 50 years) with idiopathic BPPV were recruited in the present study. For each patient, 2:1 sex and age matched healthy people were assigned as the control group. The influence of 25(OH) D levels on BPPV and recurrent BPPV were performed by binary logistic regression analysis. Results: In the present study, 174 patients with BPPV and 348 controls were included. The serum levels of 25(OH) D in those patients were lower than in those controls (P<0.001). One hundred eight patients were found to have vitamin D deficiency; thus, the prevalence was 62.1%, which was higher than that in the controls (42.8%). The data showed that patients with recurrent BPPV (N = 31) had lower serum levels of 25(OH) D compared with those who were not (11.2 ng/ml [interquartile range, 7.2–20.8 ng/ml] vs 18.7 ng/ml [14.2–24.8 ng/ml]). The regression analyses demonstrated that vitamin D deficiency was associated with BPPV and recurrent BPPV with an odds ratio of 2.15 (95% confidence interval [CI], 1.30–4.32; P=0.006) and 5.16 (95% CI, 1.00–34.12; P=0.05). Conclusion: Decreased serum levels of 25(OH)D were associated with the occurrence and recurrence of BPPV in a Chinese population, independent of other baseline markers.

Association of benign paroxysmal positional vertigo with vitamin D deficiency: a systematic review and meta-analysis

2018 ◽  
Vol 275 (11) ◽  
pp. 2705-2711 ◽  
Author(s):  
Mohammed A. AlGarni ◽  
Ahmad A. Mirza ◽  
Awwadh A. Althobaiti ◽  
Hanan H. Al-Nemari ◽  
Lamees S. Bakhsh
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Benign Paroxysmal Positional Vertigo ◽  
Meta Analysis ◽  
Positional Vertigo ◽  
Paroxysmal Positional Vertigo

scholarly journals Relation between vitamin D deficiency and benign paroxysmal positional vertigo

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Aida Ahmed Abdelmaksoud ◽  
Dalia Fahim Mohammed Fahim ◽  
Shamardan Ezzeldin Sayed Bazeed ◽  
Mohamed Farouk Alemam ◽  
Zaki Farouk Aref
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Benign Paroxysmal Positional Vertigo ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
Positional Vertigo ◽  
Group A ◽  
Group B ◽  
Repositioning Maneuver ◽  
Paroxysmal Positional Vertigo

AbstractBenign paroxysmal positional vertigo (BPPV) is the most common cause of positional vertigo. Vitamin D deficiency may be one of the causes of its development. To assess the relation between recurrent attacks BPPV and Vitamin D deficiency. A case control study in which 40 patients were clinically diagnosed as posterior canal BPPV, Serum 25(OH) D was measured at 1st visit. Patients were divided into two groups; group A (20 patients) received Vitamin D supplementation in addition to canal repositioning maneuver and group B (20 patients) treated by canal repositioning maneuver only. Follow up of all patients for 6 months, neuro-otological assessment was repeated and recurrent attacks were recorded. Serum vitamin D was repeated after 6 month. This study included 14 males and 26 females age ranged from 35 to 61 years, Average serum of 25 (OH) D at the first visit was (12.4 ± 2 ng/ml) for group A, and (12.2 ± 1.7 ng/ml) for group B, all patients had low serum level of 25(OH) D (below 20 ng/ml). Recurrent BPPV episodes, were significantly lower in group A than that of group B. There is a relation between BPPV recurrence and low serum Vitamin D.

scholarly journals Effect of vitamin D supplementation on benign paroxysmal positional vertigo recurrence: A meta-analysis

2021 ◽  
Vol 104 (2) ◽  
pp. 003685042110245
Author(s):  
Zhiling Yang ◽  
Juanli Li ◽  
Zhenzhen Zhu ◽  
Jian He ◽  
Xudong Wei ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Evaluation System ◽  
Fixed Effects ◽  
Benign Paroxysmal Positional Vertigo ◽  
Meta Analysis ◽  
Vitamin D Supplementation ◽  
Control Group ◽  
Positional Vertigo ◽  
Paroxysmal Positional Vertigo

Benign paroxysmal positional vertigo is characterized by recurrence, which exposes patients to repeated vertigo attacks. Vitamin D deficiency has been found to be a risk factor in benign paroxysmal positional vertigo, although effect of its elimination on recurrence reduction remains unknown. To determine the effect of vitamin D supplementation in preventing recurrence of benign paroxysmal positional vertigo patients with vitamin D deficiency using a meta-analysis study. We searched and retrieved relevant articles from several databases, then used the Cochrane evaluation system or Methodological Index for Non-Randomized Studies (MINORS) to assess the quality of studies. We adopted risk-ratio (RR) with corresponding 95% confidence interval (CI) to determine effect sizes, and further performed statistical analyses under a randomized- or fixed-effects model. Seven studies, comprising 602 and 731 participants in the case and control group respectively, met our inclusion criteria, and were therefore included in the meta-analysis. Assessment based on Cochrane evaluation system or MINORS revealed that most of the studies had high quality. Moreover, the randomized- model revealed that the vitamin D supplementation group had a lower recurrence rate than the control group which did not accepted vitamin D supplementation (RR = 0.41, 95% CI = 0.26–0.65, p < 0.01). Overall, these findings indicate that vitamin D supplementation can significantly lower recurrence in benign paroxysmal positional vertigo and vitamin D deficiency.

scholarly journals Effect of Vitamin D Injection in Recurrent Benign Paroxysmal Positional Vertigo with Vitamin D Deficiency

2020 ◽  
Vol 24 (04) ◽  
pp. e423-e428
Author(s):  
Gu Il Rhim
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Vitamin D3 ◽  
Benign Paroxysmal Positional Vertigo ◽  
Case Group ◽  
Control Groups ◽  
Entire Study ◽  
Positional Vertigo ◽  
Relapse Rates ◽  
Paroxysmal Positional Vertigo

Abstract Introduction There have been reports indicating that patients with frequently recurring benign paroxysmal positional vertigo (BPPV) had vitamin D deficiency, and some studies indicated that the treatment of severe vitamin D deficiency is effective in the reduction of the recurrence of BPPV. Objective The purpose of the present study was to examine the effects of Vitamin D3 injection on recurrence among patients with a 10 ng/mL or lower 25-hydroxyvitamin D blood concentration diagnosed with BPPV. Methods Among 99 patients with idiopathic BPPV with vitamin D deficiency, 25 patients (case group) were submitted to 3 to 4 injections of 200,000 IU of vitamin D3 in the first year. In total, 50 patients in the control group were selected through frequency matching, with 25 patients in the case group. Age, gender, and type of BPPV are used in matching variables with 1:2 matched data. The subjects of the study group were followed up for 24 months. Results The differences in relapse rates between the case and the control groups were examined using the non-parametric Kruskal-Wallis test for k independent samples. With regard to the relapse rates of the entire case and control groups by period, from 0 to 6 months (p < 0.531), from 7 to 12 months (p < 1.000), and from 13 to 24 months (p < 0.711), and in the entire study period (p < 0.883) there were no statistically significant differences. Conclusion The present case-control study indicated that vitamin D3 injection had no significant effect on the recurrence of BPPV patients with vitamin D deficiency when age, gender, and type of BPPV were homogeneous between the two groups.

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