In order to validate the seismic performance of reinforced concrete grid-mesh frame wall , four grid frame walls in half size is made with different height-width ratios and different grid forms in the paper. Two of them are filling with cast-in-place plaster as filling material. According to the experimental results of these four walls subjected to horizontal reciprocating loads, we know that the grid-mesh frame wall's breaking form are in stages and multiple modes, and the main influencing factors are height-width ratio and grid form, what's more, with cast-in-place plaster as fill material, could not only improve the level of the wall bearing capacity and stiffness, but also improve the ductility and seismic energy dissipation capacity.