scholarly journals Effects of the Sri Lankan medicinal plant, Salacia reticulata, in rheumatoid arthritis

2009 ◽  
Vol 5 (1) ◽  
pp. 89-96 ◽  
Author(s):  
Yuusuke Sekiguchi ◽  
Hiroshi Mano ◽  
Sachie Nakatani ◽  
Jun Shimizu ◽  
Masahiro Wada
2018 ◽  
Vol 6 (5) ◽  
pp. 16-25
Author(s):  
Anoja Priyadarshani Attanayake ◽  
Kamani Ayoma Perera Wijewardana Jayatilaka

The objectives of the study were to determine the acetylcholinesterase (AChE) inhibitory activity and antioxidant activity in the selected Sri Lankan medicinal plants. AChE inhibitory activity of the selected medicinal plant extracts was determined using the Ellman’s method. The antioxidant activities were determined by four in vitro methods namely DPPH assay, FRAP assay, NO assay and TBA acid method.  The contents of total polyphenols and flavonoids were determined quantitatively.Out of the ten selected medicinal plant extracts Abrus precatorius, Centella asiatica, Strychnos nux-vomica and Ricinus communis showed IC50 values < 200 µg/mL for AChE inhibitory activity. A high antioxidant activity was shown in the extracts of Cardiosprmum halicacabum, Centella asiatica and  Ricinus communis in  the four selected antioxidant assays.  The total polyphenol content and total flavonoid content was in the range of 0.55-7.30 mg/g DW and 19.08±0.29-1283.08± 0.09 µg/gDW. The extracts of A. precatorius, C. asiatica, S. nux-vomica and R. communis are deserved to be as potent sources of AChE inhibitors as well as natural antioxidants. Considering the complex multifactorial etiology of Alzheimer's diseases, these plant extracts would be apt candidates for the development of novel pharmaceutical agents in the management of Alzheimer's diseases.  


2009 ◽  
Vol 60 (6) ◽  
pp. 1018-1021 ◽  
Author(s):  
Joseph F. Sobanko ◽  
Alexandra F. Freeman ◽  
Tara N. Palmore ◽  
Daniel Mendoza ◽  
Chyi-Chia Richard Lee ◽  
...  

Author(s):  
Sheetal Rani ◽  
Deepika Bhatia ◽  
. Yogeeta

Urtica dioica Linn is a popular medicinal plant that is native to Europe and is very commonly found in Temperate Asia, Western and Northern Africa, America and New Zealand. It is a traditional medicine used widely in various kind of treatment as was believed to be galactagogue – a substance that promotes lactation. It is well recognized in Ayurveda due to its multidimensional pharmacological and therapeutic effects as the compress of nettle help to revive Rheumatoid arthritis, Muscle pain, Sciatic and as Rasaan tonic as it constitutes various beneficial phytochemicals. It is popularly known for its stinging action. Its chemical compounds are highly irritating mainly histamine. Traditionally, the leaves and roots are used as a blood purifier, emmenagogue, nasal hemorrhage, eczema and diarrhea.


2012 ◽  
Vol 5 (1) ◽  
pp. 198 ◽  
Author(s):  
Yuusuke Sekiguchi ◽  
Hiroshi Mano ◽  
Sachie Nakatani ◽  
Jun Shimizu ◽  
Kenji Kobata ◽  
...  

1991 ◽  
Vol 113 (3) ◽  
pp. 187-190 ◽  
Author(s):  
Krishanthi Abeywickrama ◽  
George A. Bean

2020 ◽  
Vol 259 ◽  
pp. 112933
Author(s):  
Sachinthi S. Amarasiri ◽  
Anoja P. Attanayake ◽  
Liyanagae D.A.M. Arawwawala ◽  
Kamani A.P.W. Jayatilaka ◽  
Lakmini K.B. Mudduwa

2014 ◽  
Vol 35 (3) ◽  
pp. 177-183 ◽  
Author(s):  
Anoja Priyadarshani Attanayake ◽  
Kamani Ayoma Perera Wijewardena Jayatilaka ◽  
Chitra Pathirana ◽  
Lakmini Kumari Boralugoda Mudduwa

2014 ◽  
Vol 23 (2) ◽  
pp. 221-229 ◽  
Author(s):  
G. Dhanasri ◽  
M. Srikanth Reddy ◽  
B. Naresh ◽  
Devi Cherku

An efficient protocol of axillary bud proliferation and direct organogenesis has been developed for Salacia reticulata, a highly important medicinal plant. Over-exploitation for its antidiabetic and antioxidant properties concentrated in roots and stem has caused it to be endangered, thereby the need for its conservation. Propagation of S. reticulata in vitro is a promising way for its conservation. To develop the micropropagation protocol, the germplasm was screened for selection of a suitable ecotype with high content of mangiferin estimated with High Performance Liquid Chromatography technique. Nodal segments were cultured on MS supplemented with different growth regulators. The most efficient  shoot multiplication was obtained with the supplementation of BA and IAA (3.5 + 0.5 mg/l). Elongation of the micro-shoots was achieved by subculture every 20 days. The elongated micro-shoots were efficiently rooted in vitro on half strength MS supplemented with IBA. Plantlets were successfully established in the soil in 6 - 8 weeks and were morphologically similar to those of the source plant. The protocols developed presently for direct shoot regeneration and root-induction could be successfully applied for development of high quality planting stocks. D. O. I. http://dx.doi.org/10.3329/ptcb.v23i2.17523 Plant Tissue Cult. & Biotech. 23(2): 221-229, 2013  (December)


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